TLR8 stimulation enhances cetuximab-mediated natural killer cell lysis of head and neck cancer cells and dendritic cell cross-priming of EGFR-specific CD8+ T cells
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Title
TLR8 stimulation enhances cetuximab-mediated natural killer cell lysis of head and neck cancer cells and dendritic cell cross-priming of EGFR-specific CD8+ T cells
Authors
Keywords
Cetuximab, VTX-2337, TLR8, ADCC, Head and neck cancer, Immunotherapy
Journal
CANCER IMMUNOLOGY IMMUNOTHERAPY
Volume 62, Issue 8, Pages 1347-1357
Publisher
Springer Nature
Online
2013-05-17
DOI
10.1007/s00262-013-1437-3
References
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Related references
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- Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
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- Recognition of viral single-stranded RNA by Toll-like receptors☆
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- T Regulatory Type 1 Cells in Squamous Cell Carcinoma of the Head and Neck: Mechanisms of Suppression and Expansion in Advanced Disease
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- An Exploratory Study of Systemic Administration of the Toll-like Receptor-7 Agonist 852A in Patients with Refractory Metastatic Melanoma
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- TLR7 and TLR8 as targets in cancer therapy
- (2008) M P Schön et al. ONCOGENE
- The Use of TLR7 and TLR8 Ligands for the Enhancement of Cancer Immunotherapy
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