Novel mechanism of synergistic effects of conventional chemotherapy and immune therapy of cancer

Autophagy Induced by Conventional Chemotherapy Mediates Tumor Cell Sensitivity to Immunotherapy

(2012) R. Ramakrishnan et al.   CANCER RESEARCH

Therapeutic Cancer Vaccines: Current Status and Moving Forward

(2012) J. Schlom   JNCI-Journal of the National Cancer Institute

Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells

(2012) C Gong et al.   ONCOGENE

Immune Tolerance to Tumor Antigens Occurs in a Specialized Environment of the Spleen

(2012) Stefano Ugel et al.   Cell Reports

Natural Innate and Adaptive Immunity to Cancer

(2011) Matthew D. Vesely et al.   Annual Review of Immunology

Alternative pathways for MHC class I presentation: a new function for autophagy

(2011) Magali Chemali et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype

(2010) Z.-C. Ding et al.   BLOOD

Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs

(2010) T. Nakahara et al.   BLOOD

A phase 2 pilot trial of low-dose, continuous infusion, or “metronomic” paclitaxel and oral celecoxib in patients with metastatic melanoma

(2010) Rupal S. Bhatt et al.   CANCER

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity

(2010) J. Vincent et al.   CANCER RESEARCH

Intracellular mechanisms of antigen cross presentation in dendritic cells

(2010) Sebastian Amigorena et al.   CURRENT OPINION IN IMMUNOLOGY

Chemotherapy enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice

(2010) Rupal Ramakrishnan et al.   JOURNAL OF CLINICAL INVESTIGATION

Chemotherapy Delivered After Viral Immunogene Therapy Augments Antitumor Efficacy Via Multiple Immune-mediated Mechanisms

(2010) Zvi G Fridlender et al.   MOLECULAR THERAPY

Metronomic chemotherapy: new rationale for new directions

(2010) Eddy Pasquier et al.   Nature Reviews Clinical Oncology

Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1

(2010) M Djavaheri-Mergny et al.   ONCOGENE

Pre-treatment with chemotherapy can enhance the antigenicity and immunogenicity of tumours by promoting adaptive immune responses

(2009) W M Liu et al.   BRITISH JOURNAL OF CANCER

Treg depletion with a low-dose metronomic temozolomide regimen in a rat glioma model

(2009) Claire Banissi et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Classification of Chemotherapeutic Agents Based on Their Differential In vitro Effects on Dendritic Cells

(2009) H. Tanaka et al.   CANCER RESEARCH

Clinical and Pharmacodynamic Evaluation of Metronomic Cyclophosphamide, Celecoxib, and Dexamethasone in Advanced Hormone-refractory Prostate Cancer

(2009) A. Fontana et al.   CLINICAL CANCER RESEARCH

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

(2009) Einat Zalckvar et al.   EMBO REPORTS

Paclitaxel and immune system

(2009) Aqeel Javeed et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice

(2009) Hanh K. Le et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chemotherapeutic Agents in Noncytotoxic Concentrations Increase Antigen Presentation by Dendritic Cells via an IL-12-Dependent Mechanism

(2009) G. V. Shurin et al.   JOURNAL OF IMMUNOLOGY

Autophagy Is Essential for Mitochondrial Clearance in Mature T Lymphocytes

(2009) H. H. Pua et al.   JOURNAL OF IMMUNOLOGY

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations

(2009) Ramon Kaneno et al.   Journal of Translational Medicine

Combined oral cyclophosphamide and bevacizumab in heavily pre-treated ovarian cancer

(2008) José Miguel Jurado García et al.   Clinical & Translational Oncology

Combination of Docetaxel and Recombinant Vaccine Enhances T-Cell Responses and Antitumor Activity: Effects of Docetaxel on Immune Enhancement

(2008) C. T. Garnett et al.   CLINICAL CANCER RESEARCH

Pretreatment with Cisplatin Enhances E7-Specific CD8+ T-Cell-Mediated Antitumor Immunity Induced by DNA Vaccination

(2008) C.-W. Tseng et al.   CLINICAL CANCER RESEARCH

Differential impairment of regulatory T cells rather than effector T cells by paclitaxel-based chemotherapy

(2008) Lei Zhang et al.   CLINICAL IMMUNOLOGY