Tumor-specific CD4+ T cells develop cytotoxic activity and eliminate virus-induced tumor cells in the absence of regulatory T cells

Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B

(2015) Inna S. Afonina et al.   IMMUNOLOGICAL REVIEWS

Human Circulating CD4+CD25highFoxp3+ Regulatory T Cells Kill Autologous CD8+ but Not CD4+ Responder Cells by Fas-Mediated Apoptosis

(2014) L. Strauss et al.   JOURNAL OF IMMUNOLOGY

Tumor-specific CD4+ Melanoma Tumor-infiltrating Lymphocytes

(2012) Kevin M. Friedman et al.   JOURNAL OF IMMUNOTHERAPY

Regulatory T cells inhibit acute IFN-  synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10

(2011) D. K. Sojka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells

(2011) N. R. Mahadevan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Depletion of Foxp3+ Regulatory T Cells Improves Effective Therapeutic Vaccination against Established Melanoma

(2010) K. Klages et al.   CANCER RESEARCH

Accumulation of Foxp3+ T Regulatory Cells in Draining Lymph Nodes Correlates with Disease Progression and Immune Suppression in Colorectal Cancer Patients

(2010) L. Deng et al.   CLINICAL CANCER RESEARCH

Tumor-reactive CD4+T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

(2010) Sergio A. Quezada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A role for the transcription factor Helios in human CD4+CD25+ regulatory T cells

(2010) Derese Getnet et al.   MOLECULAR IMMUNOLOGY

The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell response

(2009) G. Zelinskyy et al.   BLOOD

Differences in Tumor Regulatory T-Cell Localization and Activation Status Impact Patient Outcome

(2009) C. Menetrier-Caux et al.   CANCER RESEARCH

HLA-DR expression is associated with better prognosis in sporadic Australian clinicopathological Stage C colorectal cancers

(2009) Michael D. Walsh et al.   INTERNATIONAL JOURNAL OF CANCER

Mechanisms of control of acute Friend virus infection by CD4+ T helper cells and their functional impairment by regulatory T cells

(2009) S. R. Nair et al.   JOURNAL OF GENERAL VIROLOGY

Cutting Edge: Depletion of Foxp3+ Cells Leads to Induction of Autoimmunity by Specific Ablation of Regulatory T Cells in Genetically Targeted Mice

(2009) J. Kim et al.   JOURNAL OF IMMUNOLOGY

Toward targeting B cell cancers with CD4+CTLs: identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis

(2008) Robbert M. Spaapen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Treatment of Metastatic Melanoma with Autologous CD4+ T Cells against NY-ESO-1

(2008) Naomi N. Hunder et al.   NEW ENGLAND JOURNAL OF MEDICINE