Journal
CANCER IMMUNOLOGY IMMUNOTHERAPY
Volume 58, Issue 9, Pages 1481-1488Publisher
SPRINGER
DOI: 10.1007/s00262-009-0722-7
Keywords
CMV; Vaccine; Adoptive cellular therapy; Artificial antigen presenting cells
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Allogeneic haematopoietic stem cell transplantation (HSCT) is an intensive medical treatment involving myeloablative chemo-radiotherapy followed by stem cell rescue using allogeneic haematopoietic stem cells harvested from HLA-matched donors, which is primarily used for the treatment of haematological malignancies. Cytomegalovirus (CMV) infection is one of the major causes of morbidity and death after HSCT. This focused research review highlights the advances made with research into CMV in the HSCT setting. It provides the reader with an overview of current CMV research into the prevention and management of CMV infection.
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