Article
Oncology
Michael T. Halpern, Ya-Chen Tina Shih, K. Robin Yabroff, Donatus U. Ekwueme, Cathy J. Bradley, Amy J. Davidoff, Lindsay M. Sabik, Joseph Lipscomb
Summary: This commentary identifies important topics and questions in cancer health economics research, which will aid in the development of this critical field.
Review
Chemistry, Multidisciplinary
Brian Youden, Runqing Jiang, Andrew J. Carrier, Mark R. Servos, Xu Zhang
Summary: Despite successful clinical applications in drug delivery, the potential of theranostic nanomedicines is limited by mechanistic uncertainty and lack of science-based regulatory guidance. This review provides an overview of cancer nanomedicine field and offers knowledge framework and interaction maps to facilitate future research, assessments, and regulation. The understanding of structure-activity relationships is crucial for computer-assisted evaluation models as nanomedicine moves away from animal testing.
Article
Oncology
Heather Spencer Feigelson, Christina L. Clarke, Stephen K. Van den Eeden, Sheila Weinmann, Andrea N. Burnett-Hartman, Sarah Rowell, Shauna Goldberg Scott, Larissa L. White, Monica Ter-Minassian, Stacey A. A. Honda, Deborah R. Young, Aruna Kamineni, Terrence Chinn, Alexander Lituev, Alan Bauck, Elizabeth A. McGlynn
Summary: The Kaiser Permanente Research Bank (KPRB) has established a Cancer Cohort to study cancer survival and factors impacting treatment and prognosis. The cohort, consisting of 65,225 cases, includes diverse participants in terms of age, race/ethnicity, and geographic location. This research aims to improve our understanding of treatment efficacy and disparities in cancer survival.
Article
Oncology
Mark Lawler, Francesco De Lorenzo, Pernilla Lagergren, Francesco S. Mennini, Saronas Narbutas, Grazia Scocca, Francoise Meunier
Summary: Europe is at a watershed moment in efforts to improve survival rates and outcomes for cancer patients, with the EU Cancer Mission and European Beating Cancer Plan offering significant opportunities. Cancer research has traditionally focused on diagnosis and treatment, while survivorship has been overlooked. A European Cancer Survivorship Research and Innovation Plan is proposed to address this gap and benefit the nearly 20 million cancer survivors in Europe.
MOLECULAR ONCOLOGY
(2021)
Article
Engineering, Multidisciplinary
Jie Zhuang, Frank E. Loffler, Gary S. Sayler
Summary: This article discusses the challenges posed by urbanization, population growth, and the consumption of food, energy, and water resources for economic, environmental, and social sustainability. It proposes a research framework to promote a comprehensive understanding and quantification of the interrelationships between FEW and EES systems. The framework emphasizes increasing resource accessibility, improving coordinated interplays across sectors and scales, expanding and diversifying supply-chain networks, and innovating technologies for efficient resource utilization.
Article
Public, Environmental & Occupational Health
Giorgio Cometto, Samuel Assegid, Geta Abiyu, Mesfin Kifle, Ozge Tuncalp, Shamsuzzoha Syed, Melissa Kleine Bingham, Jennifer Nyoni, Onyema Kester Ajuebor
Summary: The progressive realisation of universal health coverage requires policies and management strategies that enable health workers to provide compassionate and respectful care. This paper explores various policy options, such as competency-based education, supportive supervision, and workforce governance, to enhance the quality of care and support health workers in fulfilling their roles and responsibilities.
Article
Nutrition & Dietetics
Danielle D. B. Holthuijsen, Martijn J. L. Bours, Eline H. van Roekel, Stephanie O. Breukink, Maryska L. G. Janssen-Heijnen, Eric T. P. Keulen, Per M. Ueland, Oivind Midttun, Stefanie Brezina, Biljana Gigic, Andrea Gsur, Dieuwertje E. Kok, Jennifer Ose, Cornelia M. Ulrich, Matty P. Weijenberg, Simone J. P. M. Eussen
Summary: The adherence to dietary recommendations of the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) and Dutch Healthy Diet (DHD) is associated with more favorable concentrations of kynurenines in colorectal cancer survivors.
Review
Oncology
Aubhishek Zaman, Trever G. Bivona
Summary: Advancements in technology and high throughput molecular data have led to a more quantitative and multidisciplinary approach in biology, accelerating the translation of laboratory findings into practical applications. The use of quantification and statistical analysis is crucial in understanding the effects and mechanisms behind translational applications. Adherence to guidelines proposed in this manuscript can improve assay design and reduce errors in translational biomarker and therapeutic applications.
Article
Oncology
Luke M. Shenton, Udara Perera, Amy Leader, Ann C. Klassen
Summary: This study investigated the challenges of smoking cessation among cancer patients and the perspectives of both patients and healthcare providers. The findings highlight the need for improving cessation services within oncology care and addressing barriers to quitting, such as therapeutic nihilism and lack of training. Standardized programs and professional education are recommended to provide evidence-based cessation services tailored to cancer patients.
INTEGRATIVE CANCER THERAPIES
(2023)
Article
Oncology
I. Vaz-Luis, M. Masiero, G. Cavaletti, A. Cervantes, R. T. Chlebowski, G. Curigliano, E. Felip, A. R. Ferreira, P. A. Ganz, J. Hegarty, J. Jeon, C. Johansen, F. Joly, K. Jordan, B. Koczwara, P. Lagergren, M. Lambertini, D. Lenihan, H. Linardou, C. Loprinzi, A. H. Partridge, S. Rauh, K. Steindorf, W. van der Graaf, L. van de Poll-Franse, G. Pentheroudakis, S. Peters, G. Pravettoni
Summary: Survivorship care consists of five main components and can be delivered through structured care models, focusing on coordinated care and educational programs.
ANNALS OF ONCOLOGY
(2022)
Article
Urology & Nephrology
Jeff Dunn, Anna Green, Nicholas Ralph, Robert U. Newton, Andrew Kneebone, Mark Frydenberg, Suzanne K. Chambers
Summary: The study aimed to develop contemporary and inclusive prostate cancer survivorship guidelines for Australia, involving a diverse expert panel to identify key descriptors of men's current survivorship experience and important elements within survivorship domains. Consensus was high on the essential nature of all identified domains, with feasibility ratings varying. Seven priorities for immediate action were derived from the study results.
Article
Oncology
Fiona Crawford-Williams, Bogda Koczwara, Raymond J. Chan, Janette Vardy, Karolina Lisy, Julia Morris, Mahesh Iddawela, Gillian Mackay, Michael Jefford
Summary: The aim of this study was to establish research and infrastructure priorities for cancer survivorship. The study surveyed Australian experts in cancer survivorship to determine the priorities in various research categories and the type of research needed. The results can be used to support coordinated action between researchers, funding bodies, and other key stakeholders.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Biodiversity Conservation
John M. Anderies, Graeme S. Cumming, Hayley S. Clements, Steven J. Lade, Ralf Seppelt, Sivee Chawla, Birgit Mueller
Summary: As conservation biology has evolved, it has become apparent that conservation problems are closely tied to human interactions. However, there is a lack of models that accurately capture the complexities of human-nature interactions. To address this, the authors propose a simple yet versatile modeling framework that combines ideas from economics, social sciences, and ecology.
BIOLOGICAL CONSERVATION
(2022)
Article
Oncology
Andrew Harper, Fiona Schulte, Gregory M. T. Guilcher, Tony H. Truong, Kathleen Reynolds, Maria Spavor, Natalie Logie, Joon Lee, Miranda M. Fidler-Benaoudia
Summary: Treatments for childhood cancer can have negative long-term effects. This study presents the Alberta Childhood Cancer Survivorship Research Program, its cohort, and statistical outcomes. The cohort consisted of 2580 childhood cancer survivors, mostly male, diagnosed between 0 and 4 years old with leukemia, CNS tumor, or lymphoma. The median time since diagnosis was 5.5 years overall and 10.4 years for 5-year survivors. During follow-up, 82 subsequent cancers were diagnosed, along with various healthcare events and deaths.
Article
Public, Environmental & Occupational Health
Joanna Mendell, Lindsey Richardson
Summary: Integrated knowledge translation (IKT) is a strategy to address barriers in using scientific evidence for public policy interventions. This case study evaluated an IKT project aimed at improving stakeholder engagement and trust, resulting in increased contextual knowledge for system change and enhanced public discourse. Sustained engagement with diverse stakeholders improved the evidence available for informing policy improvements.
