Review
Cardiac & Cardiovascular Systems
Maribel Botana-Rial, Irene Lojo-Rodriguez, Virginia Leiro-Fernandez, Cristina Ramos-Hernandez, Almudena Gonzalez-Montaos, Luis Pazos-Area, Manuel Nunez-Delgado, Alberto Fernandez-Villar
Summary: CryoEBUS has shown higher diagnostic usefulness compared to EBUS-TBNA for mediastinal and hilar involvement, especially in cases of benign pathologies and other tumor types such as lymphomas. Samples obtained by cryoEBUS also allow for better histological subtyping of lymphoma and complete molecular characterization in cases of lung cancer.
RESPIRATORY MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Terunaga Inage, Kosuke Fujino, Yamato Motooka, Tsukasa Ishiwata, Hideki Ujiie, Nicholas Bernards, Alexander Gregor, Zhenchian Chen, Masato Aragaki, Tomonari Kinoshita, Ichiro Yoshino, Kazuhiro Yasufuku
Summary: The study demonstrated the feasibility of using EBUS-TBNI for thrombolysis of pulmonary emboli, showing promising results in clot dissolution without complications in experimental pig models.
ANNALS OF THORACIC SURGERY
(2021)
Article
Medicine, General & Internal
Shi-Jie Li, Qi Wu
Summary: This study evaluated the value of EBUS-TBNA in diagnosing intrathoracic lymphadenopathy in patients with extrathoracic malignancies. The results showed that EBUS-TBNA has high sensitivity and accuracy, making it a simple and effective diagnostic method for patients with extrathoracic malignancies.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Medicine, General & Internal
Wei Liu, Yongxue Wang, Weidong Zhang, Huaiqiu Wu, Zhiguang Liu
Summary: This case report describes a 28-year-old male with mediastinal cyst diagnosed as lymphangioma through EBUS examination, with subsequent infection after the procedure and recovery following treatment. EBUS-TBNA is a useful tool for mediastinal cyst management but requires careful execution to avoid complications.
Article
Medicine, General & Internal
Huzaifa A. Jaliawala, Samid M. Farooqui, Kassem Harris, Tony Abdo, Jean I. Keddissi, Houssein A. Youness
Summary: EBUS-TBNA, as the procedure of choice for sampling hilar and mediastinal adenopathy, has been studied extensively in the last two decades. New ultrasound scanning modes and tools have been introduced to optimize target lymph node selection and sampling, potentially reducing passes, procedure time, and increasing diagnostic yield.
Article
Medicine, General & Internal
Ching-Wei Wang, Muhammad-Adil Khalil, Yi-Jia Lin, Yu-Ching Lee, Tsai-Wang Huang, Tai-Kuang Chao
Summary: Lung cancer is the leading cause of cancer deaths worldwide, and accurate nodal staging is crucial for determining treatment strategies. This paper proposes a fast, efficient, and fully automatic deep convolutional neural network system for advanced lung cancer staging using EBUS-TBNA cytological WSIs. The method achieves high precision and sensitivity in experiments, outperforming state-of-the-art models and reducing computational time compared to other methods.
Article
Respiratory System
Yan Yan, Zhilong Wang, Wanpu Yan, Shijie Li, Qi Wu
Summary: This study evaluated the efficiency of endobronchial ultrasound-guided transbronchial needle aspiration in diagnosing suspicious lymph nodes after anti-tumor therapy. The results showed that this method performed well in diagnosing mediastinal and hilar lymphadenopathy, with high sensitivity and negative predictive value.
BMC PULMONARY MEDICINE
(2022)
Article
Oncology
Samy Lachkar, Quentin Faur, Florent Marguet, Liana Veresezan, Michael Bubenheim, Mathieu Salaun, Luc Thiberville, Jean-Christophe Sabourin, Florian Guisier, Nicolas Piton
Summary: This study aimed to assess the improvement in diagnostic yield with the combination of EBUS-TBNA and EBUS-IFB compared to EBUS-TBNA alone. The results showed that the diagnostic yield was 94% when EBUS-IFB was combined with EBUS-TBNA, compared to 77% with EBUS-TBNA alone. In terms of histology, the diagnostic yield for nonmalignant conditions was 92% with the combination, compared to 69% with EBUS-TBNA alone.
Article
Multidisciplinary Sciences
Kazuhito Miyazaki, Yuya Hirasawa, Masaharu Aga, Naoto Aiko, Yusuke Hamakawa, Yuri Taniguchi, Yuki Misumi, Yoko Agemi, Tsuneo Shimokawa, Hiroyuki Hayashi, Katsuhiko Naoki, Hiroaki Okamoto
Summary: EBUS-TBNA with EchoTip ProCore can obtain sufficient specimens for pathological diagnosis with a high diagnostic accuracy rate.
SCIENTIFIC REPORTS
(2021)
Article
Oncology
Tsukasa Ishiwata, Terunaga Inage, Alexander Gregor, Yamato Motooka, Harley H. L. Chan, Nicholas Bernards, Masato Aragaki, Zhenchian Chen, Hideki Ujiie, Tomonari Kinoshita, Andrew Effat, Kazuhiro Yasufuku
Summary: A thin convex probe endobronchial ultrasound bronchoscope (TCP-EBUS) has the potential to improve the diagnostic yield for intrapulmonary lesions over conventional bronchoscopes, with greater reach and real-time sampling under ultrasound guidance.
TRANSLATIONAL LUNG CANCER RESEARCH
(2022)
Article
Medicine, General & Internal
Yasuyuki Mizumori, Yoshihiro Seri, Katsuya Hirano, Nobuya Hirata, Masaki Takenouchi, Shin Sasaki, Yasuharu Nakahara, Tetsuji Kawamura
Summary: This study aimed to verify the superiority of the newly devised cross-fanning technique in EBUS-TBNA biopsy by comparing its harvest volume with other maneuvers. The results showed that the cross-fanning technique yielded larger tissue samples, potentially increasing the volume of EBUS-TBNA biopsy specimens.
Review
Respiratory System
Jose Sanz-Santos, Pere Almagro, Komal Malik, Pablo Martinez-Camblor, Conxi Caro, Ramon Rami-Porta
Summary: The current guidelines recommend invasive staging for non-small cell lung cancer (NSCLC) with endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). However, the indication for confirming a negative EBUS-TBNA result with video-assisted mediastinoscopy (VAM) before resection varies in different guidelines. This study evaluates the evidence for the added value of confirmatory VAM after a negative EBUS-TBNA result in NSCLC mediastinal staging, and finds that confirmatory VAM can reduce the rate of unforeseen N2/3 disease, but with a high number needed to treat (NNT), and should be recommended only for specific cases yet to be defined.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2022)
Article
Surgery
Taiki Fujiwara, Takahiro Nakajima, Terunaga Inage, Yuki Sata, Takayoshi Yamamoto, Yuichi Sakairi, Hironobu Wada, Hidemi Suzuki, Masako Chiyo, Ichiro Yoshino
Summary: This study retrospectively evaluated the feasibility of using EBUS-TBNA for lymph node examination in patients previously treated for lung cancer, demonstrating high diagnostic accuracy in both detecting recurrence and nodal metastasis.
Article
Medicine, General & Internal
Fabienne Ruber, Gilles Wiederkehr, Carolin Steinack, Sylvia Holler, Peter Karl Bode, Fabian Kolbener, Daniel Peter Franzen
Summary: This study assessed the diagnostic yield (DY) and safety of combining EBUS-guided 1.5 mm mini-forceps biopsy with EBUS-TBNA for the diagnosis of mediastinal/hilar lymphadenopathy (LAD) or masses. The combined approach showed a higher DY for lung cancer and sarcoidosis diagnosis, but no significant differences in DY were found for smaller sample size subgroups such as lymphoma. Using a 1.5 mm mini-forceps for biopsy is a safe and feasible technique with superior overall DY compared to EBUS-TBNA alone.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Wei Liu, Yun Li, Lingjia Chen, Zhiguang Liu, Weidong Zhang
Summary: This article presents a case of right upper mediastinal schwannoma, including its diagnosis, treatment, and outcome. The patient underwent EBUS-TBNA, which provided cell blocks for pathological examination, confirming the diagnosis of schwannoma. Surgical excision was performed based on the EBUS-TBNA and postsurgical pathology results. The patient had an uneventful recovery and remained symptom-free during the 4-year follow-up period.