Review
Biochemistry & Molecular Biology
Alessandro Caputo, Angela D'Ardia, Francesco Sabbatino, Caterina Picariello, Chiara Ciaparrone, Pio Zeppa, Antonio D'Antonio
Summary: The standard of care for advanced non-small-cell lung cancer involves detecting actionable mutations, with the Idylla EGFR test being able to detect 51 mutations in 2.5 hours. Cytological material can be used for this test, but caution should be taken as the accuracy may be reduced when using scraped stained smears as input.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Oncology
Xuwen Lin, Yazhou Cai, Chenyu Zong, Binbin Chen, Di Shao, Hao Cui, Zheng Li, Ping Xu
Summary: This study found that performing capture-based targeted ultradeep sequencing on bronchoalveolar lavage (BAL) specimens can serve as a supplement in liquid biopsy for mutation detection and routine clinical utilization.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
(2023)
Review
Oncology
Tong Sun, Tao Zuo, Pei Hui, Guoping Cai
Summary: This study evaluated the value of KRAS mutation testing in adding cytological diagnosis of biliary duct brushings. The results showed that KRAS mutations were more common in malignant biliary brushings and had a certain specificity and sensitivity.
CANCER CYTOPATHOLOGY
(2022)
Article
Economics
Peter Kuhn, Kailing Shen
Summary: When gender requests were removed from a Chinese job board, the proportion of callbacks for men and women to gender-specific jobs increased significantly. This suggests that employers' gender preferences may be weak or outdated stereotypes. However, the ban primarily affected lower-wage jobs rather than the most gendered ones.
AMERICAN ECONOMIC REVIEW
(2023)
Review
Critical Care Medicine
Katarzyna Kotfis, Irene van Diem-Zaal, Shawniqua Williams Roberson, Marek Sietnicki, Mark van den Boogaard, Yahya Shehabi, E. Wesley Ely
Summary: The article discusses how to eliminate delirium in the ideal ICU and proposes improvements in ICU design and connectivity to create a comfortable environment for the prevention and management of delirium. The importance of humanizing ICU care is also emphasized.
Article
Medicine, General & Internal
Guodong Fu, Ronald S. Chazen, Christina MacMillan, Ian J. Witterick
Summary: This diagnostic study developed a sensitive molecular assay for detection and quantification of BRAF V600E variation in residual tissue from thyroid FNA biopsies to identify patients with cancer harboring BRAF V600E in a cost-effective manner, highlighting the clinical value of molecular assay of the remaining FNA tissue in the management of thyroid nodules.
Article
Oncology
Huang Chen, Aiping Song, Ye Wang, Yifan He, Jie Tong, Jinxi Di, Chun Li, Zhongren Zhou, Xiaopin Cai, Dingrong Zhong, Jiping Da
Summary: The study demonstrated that combining fine-needle aspiration cytology with BRAF(V600E) mutation testing can improve the accuracy of papillary thyroid cancer diagnosis, especially for thyroid nodules with indeterminate or nondiagnostic cytology.
Article
Psychology, Multidisciplinary
Karin A. Haberlin, David J. Atkin
Summary: This study utilizes Uses and Gratifications theory to explore how mobile games are used for escapism and stress coping. Findings reveal relationships between materialism and Internet addiction, as well as the role of social support in this dynamic.
COMPUTERS IN HUMAN BEHAVIOR
(2022)
Editorial Material
Geography
Harng Luh Sin
Summary: This commentary responds to the call from Jayne and Valentine (2023) to rethink the geographies of alcohol, drinking, and drunkenness. It introduces recent observations on the prevalence and absence of alcohol drinking in academic research and workspaces in China, highlighting the need for a relational approach to overcome existing impasses in alcohol studies.
DIALOGUES IN HUMAN GEOGRAPHY
(2023)
Article
Oncology
Takahiro Nozaki, Ikuko Sakamoto, Keiko Kagami, Kenji Amemiya, Yosuke Hirotsu, Hitoshi Mochizuki, Masao Omata
Summary: The study showed that genomic analysis of ascitic fluid can effectively identify genetic changes associated with epithelial ovarian cancer, providing important information for personalized precision medicine without the need for surgical intervention or biopsy. The concordance rate of molecular profiles between ascitic fluid samples and surgically resected tissues was significantly higher for oncogenic mutations compared to nononcogenic mutations.
CANCER CYTOPATHOLOGY
(2022)
Article
Environmental Sciences
Liz Koslov, Alexis Merdjanoff, Elana Sulakshana, Eric Klinenberg
Summary: After a disaster, it is important to reconsider the relationships between post-disaster relocation and rebuilding, especially in the context of accelerating climate change and associated social and policy shifts in the USA. Data shows that individuals who lived in buyout-eligible areas and chose to relocate were significantly less likely to report worsened stress compared to those who rebuilt in place.
Article
Oncology
Kei Morikawa, Hirotaka Kida, Hiroshi Handa, Takeo Inoue, Hisashi Saji, Junki Koike, Seiji Nakamura, Yoshiharu Sato, Yumi Ueda, Fumihiko Suzuki, Ryo Matoba, Masamichi Mineshita
Summary: This study prospectively evaluated the feasibility of using cytological specimens for lung cancer gene panel testing. The results showed that cytological specimens were suitable for gene analysis and had high correlations with tissue specimens for detecting gene mutations.
Article
Oncology
Joanna Ka Man Ng, Chit Chow, Ronald Cheong Kin Chan, Ka Pang Chan, Joshua Jing Xi Li, Molly Siu Ching Li, Ka-Fai To
Summary: In this study, a large cohort of EGFR tests was reviewed to evaluate the adequacy, detection rate, and discrepancy rate of cytology material. The results indicate that cytology material has lower adequacy rates, while pleural fluid is superior to pleural biopsies for molecular testing.
Article
Oncology
Pimpin Incharoen, Artit Jinawath, Lalida Arsa, Kaettipong Kamprerasart, Narumol Trachu, Nanamon Monnamo, Khantong Khiewngam, Dittapol Muntham, Phichai Chansriwong, Ekaphop Sirachainan, Thanyanan Reungwetwattana
Summary: This study explores the clinical correlates of ctDNA and tissue/plasma-based gene mutation status in different stages of NSCLC. The results show that ctDNA levels are variable and not significantly associated with clinical/surgical parameters in early-stage patients, but the clinical value of ctDNA testing is higher in advanced-stage and recurrent NSCLC. Therefore, using ctDNA testing in advanced-stage and recurrent NSCLC is feasible.
Article
Oncology
Tong Sun, Lloyd Hutchinson, Keith Tomaszewicz, Mandi-Lee Caporelli, Xiuling Meng, Kathleen McCauley, Andrew H. Fischer, Ediz F. Cosar, Kristine M. Cornejo
Summary: The study demonstrates that a bladder-specific NGS panel can improve the diagnostic utility of urine cytology in both low- and high-grade tumors, and may serve as a noninvasive surveillance method in the follow-up of patients with UC.
CANCER CYTOPATHOLOGY
(2021)
Article
Oncology
M. E. Rodriguez-Ruiz, J. L. Perez-Gracia, I Rodriguez, C. Alfaro, C. Onate, G. Perez, I Gil-Bazo, A. Benito, S. Inoges, A. Lopez-Diaz de Cerio, M. Ponz-Sarvise, L. Resano, P. Berraondo, B. Barbes, S. Martin-Algarra, A. Gurpide, M. F. Sanmamed, C. de Andrea, A. M. Salazar, I Melero
ANNALS OF ONCOLOGY
(2018)
Article
Oncology
I. Eguren-Santamaria, R. Sanchez-Bayona, A. Patino-Garcia, Ignacio Gil-Bazo, J. M. Lopez-Picazo
Review
Biochemistry & Molecular Biology
Marta Roman, Iosune Baraibar, Ines Lopez, Ernest Nadal, Christian Rolfo, Silvestre Vicent, Ignacio Gil-Bazo
Review
Oncology
F. Passiglia, C. Caglevic, E. Giovannetti, J. A. Pinto, P. Manca, S. Taverna, A. Listi, I. Gil-Bazo, L. E. Raez, A. Russo, C. Rolfo
SEMINARS IN CANCER BIOLOGY
(2018)
Article
Oncology
Juan Pablo Fusco, Guillermo Pita, Maria Jose Pajares, Maria Pilar Andueza, Ana Patino-Garcia, Juan P. de-Torres, Alfonso Gurpide, Javier Zulueta, Rosario Alonso, Nuria Alvarez, Ruben Rio, Ignacio I. Melero, Miguel F Sanmamed, Maria Rodriguez Ruiz, Ignacio I. Gil-Bazo, Jose Maria Lopez-Picazo, Giro Casanova, Rebeca Baz Davila, Antonio Agudo, Maria Dolores Lozano, Alvaro Gonzalez, Nuria Sala, Eva Ardanaz, Javier Benitez, Luis Montuenga, Anna Gonzalez-Neira, Jose Luis Perez-Gracia
Article
Multidisciplinary Sciences
Rocio Figueroa, Ana Alfonso, Jose Lopez-Picazo, Ignacio Gil-Bazo, Alberto Garcia-Mouriz, Jose Hermida, Jose Antonio Paramo, Ramon Lecumberri
Article
Critical Care Medicine
Michael Duruisseaux, Anna Martinez-Cardus, Maria E. Calleja-Cervantes, Sebastian Moran, Manuel Castro de Moura, Veronica Davalos, David Pineyro, Montse Sanchez-Cespedes, Nicolas Girard, Marie Brevet, Etienne Giroux-Leprieur, Coraline Dumenil, Monica Pradotto, Paolo Bironzo, Enrica Capelletto, Silvia Novello, Alexis Cortot, Marie-Christine Copin, Niki Karachaliou, Maria Gonzalez-Cao, Sergio Peralta, Luis M. Montuenga, Ignacio Gil-Bazo, Iosune Baraibar, Maria D. Lozano, Mar Varela, Jose C. Ruffinelli, Ramon Palmero, Ernest Nadal, Teresa Moran, Lidia Perez, Immaculada Ramos, Qingyang Xiao, Agustin F. Fernandez, Mario F. Fraga, Marta Gut, Ivo Gut, Cristina Teixido, Noelia Vilarino, Aleix Prat, Noemi Reguart, Amparo Benito, Pilar Garrido, Isabel Barragan, Jean-Francois Emile, Rafael Rosell, Elisabeth Brambilla, Manel Esteller
LANCET RESPIRATORY MEDICINE
(2018)
Article
Oncology
Marta Roman, Ines Lopez, Elisabeth Guruceaga, Iosune Baraibar, Margarita Ecay, Maria Collantes, Ernest Nadal, Adrian Vallejo, Silvia Cadenas, Marta Echavarri-de Miguel, Jae Hwi Jang, Patxi San Martin-Uriz, Laura Castro-Labrador, Amaia Vilas-Zornoza, David Lara-Astiaso, Mariano Ponz-Sarvise, Christian Rolfo, Edgardo S. Santos, Luis E. Raez, Simona Taverna, Carmen Behrens, Walter Weder, Ignacio I. Wistuba, Silvestre Vicent, Ignacio Gil-Bazo
Article
Oncology
R. Figueroa, A. Alfonso, J. Lopez-Picazo, I. Gil-Bazo, A. Garcia-Mouriz, J. Hermida, J. A. Paramo, R. Lecumberri
CLINICAL & TRANSLATIONAL ONCOLOGY
(2019)
Article
Respiratory System
Elena Martinez-Terroba, Carmen Behrens, Jackeline Agorreta, Eduard Monso, Laura Millares, Enriqueta Felip, Rafael Rosell, Jose Luis Ramirez, Ana Remirez, Wenceslao Torre, Ignacio Gil-Bazo, Miguel A. Idoate, Juan P. de-Torres, Ruben Pio, Ignacio I. Wistuba, Maria J. Pajares, Luis M. Montuenga
Article
Oncology
Jae-Hwi Jang, Florian Janker, Ingrid De Meester, Stephan Arni, Nathalie Borgeaud, Yoshito Yamada, Ignacio Gil Bazo, Walter Weder, Wolfgang Jungraithmayr
Article
Oncology
Pablo Reclusa, Jean-Francois Laes, Umberto Malapelle, Anna Valentino, Danilo Rocco, Ignacio Gil-Bazo, Christian Rolfo
TRANSLATIONAL CANCER RESEARCH
(2019)
Meeting Abstract
Oncology
D. Rodriguez-Abreu, J. Campillo, F. Grau, E. Carcereny, R. Bernabe, Y. Garcia, A. Artal Cortes, M. Gonzalez Cao, O. Juan, F. Garicano, I. Gil-Bazo, R. Blanco, M. Guillot, M. Provencio, M. Majem
JOURNAL OF THORACIC ONCOLOGY
(2018)
Meeting Abstract
Oncology
I. Gil-Bazo, I. Baraibar, M. Roman Moreno, I. Lopez, J. Corral, J. Lasarte, A. Calvo, S. Vicent, D. Ajona
JOURNAL OF THORACIC ONCOLOGY
(2018)
Meeting Abstract
Oncology
J. Jang, S. Hillinger, M. Haberecker, A. Curioni Fontecedro, F. Janker, I. Gil-Bazo, I. Hwang, K. Kwon, W. Weder, A. Soltermann, W. Jungraithmayr
JOURNAL OF THORACIC ONCOLOGY
(2018)
