Article
Clinical Neurology
V. Millischer, S. Pramhas, I. Wiedermann, V. Eder, H. G. Kress, A. Michalek-Sauberer, D. Rujescu, R. Frey, P. Baldinger-Melich
Summary: This retrospective study compared the effects of etomidate and methohexital as anesthetic agents in ECT treatment. The results showed that etomidate was inferior to methohexital, as it led to longer procedure duration and poor side effects.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Medicine, General & Internal
Young Tak Jo, Sung Woo Joo, Jungsun Lee, Yeon Ho Joo
Summary: This study reviewed 268 bitemporal ECT sessions in a university hospital from December 2006 to July 2018, and found that the use of etomidate was significantly associated with post-ECT delirium. The risk of post-ECT delirium increased with etomidate use, highlighting the importance for practitioners to consider this risk when choosing anesthetics.
Article
Clinical Neurology
Kannapas Kittayarak, Pichai Ittasakul
Summary: The practice of electroconvulsive therapy (ECT) in Thailand has seen significant development over the past two decades, with the majority of patients now being treated with modified ECT. The use of pre-treatment investigations, devices providing brief pulses, unilateral electrode placement, and monitoring of treatment parameters has also become more widespread to enhance treatment efficacy and minimize side effects. However, there are still areas for improvement, such as promoting ECT education among psychiatrists and psychiatry residents.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2022)
Article
Behavioral Sciences
Kevin J. J. Li, Natalie E. Slama, Matthew E. Hirschtritt, Prachi Anshu, Esti Iturralde
Summary: This study examined the clinical outcomes of using etomidate and methohexital as anesthetics for electroconvulsive therapy (ECT) in the United States. It found that the choice of anesthetic did not significantly affect depression remission, emergency department visits, or hospitalizations 12 months after treatment. However, etomidate use was associated with a higher rate of patient discomfort adverse effects compared to methohexital. Clinicians should consider other patient or treatment characteristics when deciding on anesthetics for ECT.
Review
Biology
Kevin Lee, Kimberly D. Jenkins, Tanaya Sparkle
Summary: Electroconvulsive therapy (ECT) is an effective treatment for severe psychiatric disorders, and providing appropriate anesthesia for ECT is challenging, requiring consideration of the patient's condition and associated risks.
Article
Clinical Neurology
Hong Li, Lingzhi Hou, Dong Wang, Qijin Wu, Haijin Li, Wen He, Sheng Li, Jianyue Pang, Yanyan Zhang, Quangang Ma, Cai Li, Jun Cheng
Summary: This study found that the combination of antidepressants and electroconvulsive therapy (ECT) is highly effective and safe for treating depression in both adolescents and adults. Depressed adolescents expressed stronger suicidal intent, which was alleviated by ECT. There were no significant differences in depression symptoms and treatment outcomes between adolescents and adults, and the side effects were similar.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Nujaree Sombatcharoen-non, Thidarat Yamnim, Sudawan Jullagate, Pichai Ittasakul
Summary: This retrospective mirror-image study found that continuation-maintenance electroconvulsive therapy (ECT) can effectively reduce psychiatric hospitalizations and admission days in Thai patients with various psychiatric diagnoses.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2023)
Article
Clinical Neurology
Santiago Madero, Gerard Anmella, Maria Sague-Vilavella, Maria Teresa Pons, Anna Gimenez, Andrea Murru, Marta Gomez-Ramiro, Joaquin Gil-Badenes, Jose Rios, Miquel Bioque, Eduard Vieta, Antonio Benabarre
Summary: This study aimed to investigate the real-life effectiveness of maintenance electroconvulsive therapy(mECT) in bipolar disorder(BD). The results showed that mECT can effectively reduce the number and duration of psychiatric hospitalizations in BD patients, supporting its effectiveness in the treatment of BD.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Santiago Madero, Gerard Anmella, Maria Sague-Vilavella, Maria Teresa Pons, Anna Gimenez, Andrea Murru, Marta Gomez-Ramiro, Joaquin Gil-Badenes, Jose Rios, Miquel Bioque, Eduard Vieta, Antonio Benabarre
Summary: This study aimed to investigate the effectiveness of maintenance electroconvulsive therapy (mECT) in treating bipolar disorder (BD). The results showed that mECT had a 62.2% effectiveness in preventing psychiatric hospitalizations and significantly reduced the number of hospitalization days and admissions for BD patients.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Medicine, General & Internal
Randall T. Espinoza, Charles H. Kellner
Summary: Update on Electroconvulsive Therapy (ECT): ECT is effective for several disorders, notably severe or treatment-resistant depression, showing rapid response. However, stigma hampers its usage. The mechanism remains unknown, but a seizure is necessary for efficacy. ECT prominently affects memory, albeit transiently.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Psychiatry
Isabel Methfessel, Matthias Besse, Michael Belz, David Zilles-Wegner
Summary: This study found that reducing or discontinuing c-/m-ECT treatment can lead to significant clinical deterioration, including rehospitalizations and new courses of ECT. During the COVID-19 pandemic, modifications to treatment plans had a significant impact on the clinical outcomes of patients.
ACTA PSYCHIATRICA SCANDINAVICA
(2021)
Review
Psychology, Multidisciplinary
Marco M. Zierhut, Renaldo M. Bernard, Eleanor Turner, Sara Mohamad, Eric Hahn, Malek Bajbouj
Summary: ECT holds promise as a treatment option for negative symptoms in schizophrenia, but the existing evidence is limited and methodological shortcomings are present. Future research should focus on negative symptoms, include longer follow up periods, incorporate control groups, and possibly establish multicentered studies to improve the study population.
CURRENT PSYCHOLOGY
(2023)
Article
Psychiatry
Neera Ghaziuddin, Tareq Yaqub, Wael Shamseddeen, Priyanka Reddy, Hannah Reynard, Daniel Maixner
Summary: The study aimed to investigate the naturalistic clinical course in adolescent and young adult patients with developmental delays and catatonia, when maintenance electroconvulsive therapy (M-ECT) frequency was reduced due to COVID-19 restrictions. Participants showed significant decline in symptoms, particularly motor symptoms, leading to rehospitalization for some patients.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Medicine, General & Internal
Virginie Moulier, Julien Guehl, Emilie Eveque-Mourroux, Pierre Quesada, Maud Rotharmel
Summary: The objective of this study was to determine the relationship between clinical response and postictal suppression indicators during ECT treatment. The results showed that postictal suppression from the first ECT session can predict long-term clinical response, but not early clinical response. Postictal suppression frequency was not associated with clinical response, and there was also no association between postictal suppression and short-term cognitive performance.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Zhi-De Deng, Miklos Argyelan, Jeremy Miller, Davin K. Quinn, Megan Lloyd, Thomas R. Jones, Joel Upston, Erik Erhardt, Shawn M. McClintock, Christopher C. Abbott
Summary: This study investigates the mechanisms of ECT treatment and highlights a linear relationship between right hippocampal E-field strength, neuroplasticity, antidepressant outcomes, and cognitive results. Additionally, it reveals a direct correlation between right hippocampal E-field and cognitive outcomes.
MOLECULAR PSYCHIATRY
(2022)
Review
Orthopedics
Preet Mohinder Singh, Anuradha Borle, Anjan Trikha, Lia Michos, Ashish Sinha, Basavana Goudra
JOURNAL OF ARTHROPLASTY
(2017)
Review
Pharmacology & Pharmacy
Preet Mohinder Singh, Anuradha Borle, Jeetinder Kaur Makkar, Anjan Trikha, David Fish, Ashish Sinha
JOURNAL OF CLINICAL PHARMACOLOGY
(2018)
Letter
Surgery
Preet Mohinder Singh, Anuradha Borle, Jason McGavin, Anjan Trikha, Ashish Sinha
Review
Pharmacology & Pharmacy
Preet Mohinder Singh, Anuradha Borle, Rajesh Panwar, Jeetinder Kaur Makkar, Ian McGrath, Anjan Trikha, Ashish Sinha
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
(2018)
Article
Anesthesiology
M. Neethu, Ravinder Kumar Pandey, Ankur Sharma, VanlaInghaka Darlong, Jyotsna Punj, Renu Sinha, Preet Mohinder Singh, Nandini Hamshi, Rakesh Garg, Chandralekha Chandralekha, Anurag Srivastava
JOURNAL OF CLINICAL ANESTHESIA
(2018)
Article
Gastroenterology & Hepatology
Basavana Goudra, Preet Mohinder Singh, Gary R. Lichtenstein
DIGESTIVE DISEASES AND SCIENCES
(2020)
Review
Medicine, General & Internal
Pascal Richard David Clephas, Sanne Elisabeth Hoeks, Marialena Trivella, Christian S. Guay, Preet Mohinder Singh, Markus Klimek, Michael Heesen
Summary: This study aims to summarize the evidence on prognostic factors for chronic post-surgical pain after lung or pleural surgery through systematic reviews and meta-analyses, in order to understand the influencing factors. A large number of relevant studies will be searched and evaluated, with quality assessment and data extraction conducted based on standardized criteria.
Review
Anesthesiology
N. P. Singh, D. Monks, J. K. Makkar, A. Palanisamy, P. Sultan, P. M. Singh
Summary: Comparing the efficacy of injecting local anaesthetic at different sites for postoperative pain management after caesarean delivery found varying reductions in morphine equivalents and dynamic pain scores. There was no single preferred route of injection for optimal pain relief. Confidence in effect sizes was categorized as low or very low.
Letter
Anesthesiology
P. M. Singh, A. Borle, D. Monks
Article
Obstetrics & Gynecology
David Thomas Monks, Arvind Palanisamy, Danish Jaffer, Preet Mohinder Singh, Ebony Carter, Shannon Lenze
Summary: The study assessed the feasibility of using ketamine to prevent postpartum depression after cesarean delivery and found that both subcutaneous and intravenous administration routes were well tolerated. Further research on these interventions to prevent and possibly treat postpartum depression is warranted.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Review
Medicine, General & Internal
David Thomas Monks, Basavaraj Ankalagi, Preet Mohinder Singh, Ebony Carter, Michelle Doering, Meg Guard, Shannon Lenze
Summary: This article describes a systematic review that will assess the effectiveness and acceptability of interventions for preventing and treating postpartum depression. The review will compare different types of interventions and use network meta-analysis to evaluate their efficacy.
SYSTEMATIC REVIEWS
(2022)
Review
Anesthesiology
P. R. D. Clephas, S. E. Hoeks, P. M. Singh, C. S. Guay, M. Trivella, M. Klimek, M. Heesen
Summary: This systematic review with meta-analysis aimed to identify and summarise the evidence of all prognostic factors for chronic post-surgical pain after lung and pleural surgery. The study found that patients with higher postoperative pain intensity, severe pre-operative pain, and longer surgery duration are more likely to develop chronic post-surgical pain. On the other hand, intercostal nerve block and video-assisted thoracic surgery can decrease the risk of chronic post-surgical pain. Age and sex were not found to have a significant effect on chronic post-surgical pain.
Article
Anesthesiology
D. T. Monks, P. M. Singh, L. Kagan, A. Palanisamy
Summary: Oxytocin is commonly used for preventing postpartum hemorrhage after cesarean delivery, but initial treatment failure rates are high and optimal dosing remains uncertain. This study aimed to investigate the pharmacokinetics and pharmacodynamics of oxytocin in order to determine the most effective weight-based dosing strategy.
Review
Anesthesiology
Preet M. Singh, Pervez Sultan, James O'Carroll, Lindsay Blake, Brendan Carvalho, Narinder P. Singh, David T. Monks
Summary: This article conducted a systematic review and network meta-analysis to compare the relative efficacy of different interventions in reducing the incidence of pruritus induced by single-shot intrathecal or epidural morphine in Caesarean delivery. The results showed that some interventions can effectively reduce the incidence of pruritus.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Letter
Gastroenterology & Hepatology
Basavana Goudra, Preet Mohinder Singh
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2017)