Heat shock protein 90 (HSP90) is overexpressed in p16-negative oropharyngeal squamous cell carcinoma, and its inhibition in vitro potentiates the effects of chemoradiation

A first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid malignancies

(2013) Jonathan W Goldman et al.   BMC CANCER

Enhanced Radiation Sensitivity in HPV-Positive Head and Neck Cancer

(2013) R. J. Kimple et al.   CANCER RESEARCH

Long-Term Results of RTOG 91-11: A Comparison of Three Nonsurgical Treatment Strategies to Preserve the Larynx in Patients With Locally Advanced Larynx Cancer

(2012) Arlene A. Forastiere et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab

(2011) Toni M. Brand et al.   CANCER BIOLOGY & THERAPY

TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence

(2011) H. D. Skinner et al.   CLINICAL CANCER RESEARCH

Assembly and Initial Characterization of a Panel of 85 Genomically Validated Cell Lines from Diverse Head and Neck Tumor Sites

(2011) M. Zhao et al.   CLINICAL CANCER RESEARCH

Prognostic Significance of p16INK4Aand Human Papillomavirus in Patients With Oropharyngeal Cancer Treated on TROG 02.02 Phase III Trial

(2010) Danny Rischin et al.   JOURNAL OF CLINICAL ONCOLOGY

Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer

(2010) K. Kian Ang et al.   NEW ENGLAND JOURNAL OF MEDICINE

HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer

(2009) Pernille Lassen et al.   RADIOTHERAPY AND ONCOLOGY

Inverse Relationship between Human Papillomavirus-16 Infection and Disruptive p53 Gene Mutations in Squamous Cell Carcinoma of the Head and Neck

(2008) W. H. Westra et al.   CLINICAL CANCER RESEARCH

EGFR, p16, HPV Titer, Bcl-xL and p53, Sex, and Smoking As Indicators of Response to Therapy and Survival in Oropharyngeal Cancer

(2008) Bhavna Kumar et al.   JOURNAL OF CLINICAL ONCOLOGY

Distinct Risk Factor Profiles for Human Papillomavirus Type 16–Positive and Human Papillomavirus Type 16–Negative Head and Neck Cancers

(2008) Maura L. Gillison et al.   JNCI-Journal of the National Cancer Institute