miR-181b modulates glioma cell sensitivity to temozolomide by targeting MEK1

MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer

(2011) Hiroshi Hirata et al.   CARCINOGENESIS

Chemoresistance to Temozolomide in Human Glioma Cell Line U251 is Associated with Increased Activity of O 6-methylguanine-DNA Methyltransferase and Can be Overcome by Metronomic Temozolomide Regimen

(2011) Qiang Pan et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Anti-microRNA-222 (Anti-miR-222) and -181B Suppress Growth of Tamoxifen-resistant Xenografts in Mouse by Targeting TIMP3 Protein and Modulating Mitogenic Signal

(2011) Yuanzhi Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MEK-ERK Signaling Dictates DNA-Repair Gene MGMT Expression and Temozolomide Resistance of Stem-Like Glioblastoma Cells via the MDM2-p53 Axis

(2011) Atsushi Sato et al.   STEM CELLS

The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma

(2010) Feng Zhi et al.   EUROPEAN JOURNAL OF CANCER

Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin

(2010) Igor P. Pogribny et al.   INTERNATIONAL JOURNAL OF CANCER

miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines

(2010) Wei Zhu et al.   INTERNATIONAL JOURNAL OF CANCER

MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients

(2010) O. Slaby et al.   NEOPLASMA

miR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastoma

(2010) Shyamal D. Weeraratne et al.   NEURO-ONCOLOGY

Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1

(2009) Zhongxing Liang et al.   BIOCHEMICAL PHARMACOLOGY

MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme

(2009) Yiming Li et al.   BRAIN RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

miR-21 and 221 upregulation and miR-181b downregulation in human grade II–IV astrocytic tumors

(2009) Alfredo Conti et al.   JOURNAL OF NEURO-ONCOLOGY

Systematic analysis of microRNA involved in resistance of the MCF-7 human breast cancer cell to doxorubicin

(2009) Guo-Qing Chen et al.   MEDICAL ONCOLOGY

MicroRNAs as potential cancer therapeutics

(2009) P Trang et al.   ONCOGENE

TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3

(2009) B Wang et al.   ONCOGENE

Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells

(2008) Yasunori Fujita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance

(2008) Fuxiao Xin et al.   BIOINFORMATICS

IFN- -mediated inhibition of MAPK phosphatase expression results in prolonged MAPK activity in response to M-CSF and inhibition of proliferation

(2008) A. F. Valledor et al.   BLOOD

hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells

(2008) Lei Shi et al.   BRAIN RESEARCH

Tandem Duplication Producing a Novel OncogenicBRAFFusion Gene Defines the Majority of Pilocytic Astrocytomas

(2008) David T.W. Jones et al.   CANCER RESEARCH

Tumour cell survival signalling by the ERK1/2 pathway

(2008) K Balmanno et al.   CELL DEATH AND DIFFERENTIATION

Role of microRNAs in drug-resistant ovarian cancer cells

(2008) Antonio Sorrentino et al.   GYNECOLOGIC ONCOLOGY

MicroRNA-221/222 Negatively Regulates Estrogen Receptorα and Is Associated with Tamoxifen Resistance in Breast Cancer

(2008) Jian-Jun Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correlation of O6-Methylguanine Methyltransferase (MGMT) Promoter Methylation With Clinical Outcomes in Glioblastoma and Clinical Strategies to Modulate MGMT Activity

(2008) Monika E. Hegi et al.   JOURNAL OF CLINICAL ONCOLOGY

MicroRNAs and noncoding RNAs in hematological malignancies: molecular, clinical and therapeutic implications

(2008) M Fabbri et al.   LEUKEMIA

Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin

(2008) O. Kovalchuk et al.   MOLECULAR CANCER THERAPEUTICS

Polyploidy in atypical grade II choroid plexus papilloma of the posterior fossa

(2008) María Sol Brassesco et al.   NEUROPATHOLOGY