In vitro cytotoxicity, pharmacokinetics, tissue distribution, and metabolism of small-molecule protein kinase D inhibitors, kb-NB142-70 and kb-NB165-09, in mice bearing human cancer xenografts

A protein kinase C/protein kinase D pathway protects LNCaP prostate cancer cells from phorbol ester-induced apoptosis by promoting ERK1/2 and NF-κB activities

(2011) Jun Chen et al.   CARCINOGENESIS

Design, Synthesis, and Biological Evaluation of PKD Inhibitors

(2011) Kara M. George et al.   Pharmaceutics

Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells

(2010) Sharon A. Matthews et al.   BIOCHEMICAL JOURNAL

Protein kinase D1 promotes anchorage-independent growth, invasion, and angiogenesis by human pancreatic cancer cells

(2010) Nobuo Ochi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivo

(2010) K. B. Harikumar et al.   MOLECULAR CANCER THERAPEUTICS

Synthesis and Structure−Activity Relationships of Benzothienothiazepinone Inhibitors of Protein Kinase D

(2010) Karla Bravo-Altamirano et al.   ACS Medicinal Chemistry Letters

Protein Kinase D1-Mediated Phosphorylation and Subcellular Localization of  -Catenin

(2009) C. Du et al.   CANCER RESEARCH

Protein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease-activated receptor 2

(2009) Silvia Amadesi et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells

(2009) S Hassan et al.   ONCOGENE

Protein kinase D1 (PKD1) influences androgen receptor (AR) function in prostate cancer cells

(2008) Paul Mak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protein Kinase D3 (PKD3) Contributes to Prostate Cancer Cell Growth and Survival Through a PKC /PKD3 Pathway Downstream of Akt and ERK 1/2

(2008) J. Chen et al.   CANCER RESEARCH

PKD3 Is the Predominant Protein Kinase D Isoform in Mouse Exocrine Pancreas and Promotes Hormone-induced Amylase Secretion

(2008) L. Andy Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Potent and Selective Disruption of Protein Kinase D Functionality by a Benzoxoloazepinolone

(2008) Elizabeth R. Sharlow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PKD, PKD2, and p38 MAPK mediate Hsp27 serine-82 phosphorylation induced by neurotensin in pancreatic cancer PANC-1 cells

(2007) Jingzhen Yuan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY