Gene therapy with RNAi targeting UHRF1 driven by tumor-specific promoter inhibits tumor growth and enhances the sensitivity of chemotherapeutic drug in breast cancer in vitro and in vivo

UHRF1 depletion causes a G2/M arrest, activation of DNA damage response and apoptosis

(2011) Amy L. Tien et al.   BIOCHEMICAL JOURNAL

UHRF1 is a novel diagnostic marker of lung cancer

(2010) M Unoki et al.   BRITISH JOURNAL OF CANCER

UHRF1 confers radioresistance to human breast cancer cells

(2010) Xinli Li et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Drug discovery targeting epigenetic codes: The great potential of UHRF1, which links DNA methylation and histone modifications, as a drug target in cancers and toxoplasmosis

(2009) Motoko Unoki et al.   BIOCHEMICAL PHARMACOLOGY

UHRF1 inhibits MDR1 gene transcription and sensitizes breast cancer cells to anticancer drugs

(2009) Wei Jin et al.   BREAST CANCER RESEARCH AND TREATMENT

UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells

(2008) Jong Kyong Kim et al.   NUCLEIC ACIDS RESEARCH