Kinase activation profile associated with TGF-β-dependent migration of HCC cells: a preclinical study

Essential Role of TGF-β Signaling in Glucose-Induced Cell Hypertrophy

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Targeting transforming growth factor (TGF)-βRI inhibits activation of β1 integrin and blocks vascular invasion in hepatocellular carcinoma

(2009) Emilia Fransvea et al.   HEPATOLOGY

Inhibition of transforming growth factor β receptor I kinase blocks hepatocellular carcinoma growth through neo-angiogenesis regulation

(2009) Antonio Mazzocca et al.   HEPATOLOGY

Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells

(2008) Emilia Fransvea et al.   HEPATOLOGY

Optimization of a Dihydropyrrolopyrazole Series of Transforming Growth Factor-β Type I Receptor Kinase Domain Inhibitors: Discovery of an Orally Bioavailable Transforming Growth Factor-β Receptor Type I Inhibitor as Antitumor Agent

(2008) Hong-yu Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

LY2109761, a novel transforming growth factor   receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

(2008) D. Melisi et al.   MOLECULAR CANCER THERAPEUTICS

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE