The role of peptide and DNA vaccines in myeloid leukemia immunotherapy

New insights into antigen specific immunotherapy for chronic myeloid leukemia

(2012) Yangqiu Li et al.   Cancer Cell International

Adjuvants for immunotherapy

(2012) Oliver Pfaar et al.   Current Opinion in Allergy and Clinical Immunology

Therapeutic advancement of chronic lymphocytic leukemia

(2012) Kang Lu et al.   Journal of Hematology & Oncology

Alternative expression of TCRζ related genes in patients with chronic myeloid leukemia

(2012) Xianfeng Zha et al.   Journal of Hematology & Oncology

In situ RHAMM protein expression in acute myeloid leukemia blasts suggests poor overall survival

(2011) Alexandar Tzankov et al.   ANNALS OF HEMATOLOGY

High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells

(2011) C. Quintarelli et al.   BLOOD

Enhancement of specific cellular immune response induced by glycosyl-phosphatidylinositol-anchored BCR/ABL and mIL-12

(2011) Kun Tao et al.   CANCER BIOLOGY & THERAPY

Wilms' tumor protein 1 (WT1) peptide vaccination in AML patients: predominant TCR CDR3β sequence associated with remission in one patient is detectable in other vaccinated patients

(2011) Sebastian Ochsenreither et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A meta-analysis of CAG (cytarabine, aclarubicin, G-CSF) regimen for the treatment of 1029 patients with acute myeloid leukemia and myelodysplastic syndrome

(2011) Guoqing Wei et al.   Journal of Hematology & Oncology

DNA vaccines against cancer come of age

(2010) Freda K Stevenson et al.   CURRENT OPINION IN IMMUNOLOGY

WT1 peptide vaccine induces reduction in minimal residual disease in an Imatinib-treated CML patient

(2010) Yusuke Oji et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Repeated PR1 and WT1 peptide vaccination in Montanide-adjuvant fails to induce sustained high-avidity, epitope-specific CD8+ T cells in myeloid malignancies

(2010) K. Rezvani et al.   HAEMATOLOGICA

High-dose RHAMM-R3 peptide vaccination for patients with acute myeloid leukemia, myelodysplastic syndrome and multiple myeloma

(2010) J. Greiner et al.   HAEMATOLOGICA

Enhancement of specific cellular immune response induced by DNA vaccines encoding PML-RARαand hIL-2 genes

(2010) Dongzhi Cen et al.   Hematology

DNA vaccines: an historical perspective and view to the future

(2010) Margaret A. Liu   IMMUNOLOGICAL REVIEWS

“Wilms Tumor Protein 1” (WT1) Peptide Vaccination-induced Complete Remission in a Patient With Acute Myeloid Leukemia Is Accompanied by the Emergence of a Predominant T-cell Clone Both in Blood and Bone Marrow

(2010) Sebastian Ochsenreither et al.   JOURNAL OF IMMUNOTHERAPY

BCR-ABL peptide vaccination in healthy subjects: Immunological responses are equivalent to those in chronic myeloid leukaemia patients

(2010) José M. Rojas et al.   LEUKEMIA RESEARCH

WT1 peptide vaccination in a CML patient: induction of effective cytotoxic T lymphocytes and significance of peptide administration interval

(2010) Anri Saitoh et al.   MEDICAL ONCOLOGY

DNA vaccination with all-trans retinoic acid treatment induces long-term survival and elicits specific immune responses requiring CD4+ and CD8+ T-cell activation in an acute promyelocytic leukemia mouse model

(2009) K. Furugaki et al.   BLOOD

A clinical and immunologic phase 2 trial of Wilms tumor gene product 1 (WT1) peptide vaccination in patients with AML and MDS

(2009) U. Keilholz et al.   BLOOD

Synthetic tumor-specific breakpoint peptide vaccine in patients with chronic myeloid leukemia and minimal residual disease

(2009) Nitin Jain et al.   CANCER

DNA Vaccination with Electroporation Induces Increased Antibody Responses in Patients with Prostate Cancer

(2009) Lindsey Low et al.   HUMAN GENE THERAPY

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

(2009) Tilmann Bürckstümmer et al.   NATURE IMMUNOLOGY

DNA vaccination induces WT1-specific T-cell responses with potential clinical relevance

(2008) C. Chaise et al.   BLOOD

Cytotoxic T lymphocytes directed to the preferentially expressed antigen of melanoma (PRAME) target chronic myeloid leukemia

(2008) C. Quintarelli et al.   BLOOD

A pilot vaccination trial of synthetic analog peptides derived from the BCR-ABL breakpoints in CML patients with minimal disease

(2008) P G Maslak et al.   LEUKEMIA

Hematopoietic stem cells and progenitors of chronic myeloid leukemia express leukemia-associated antigens: implications for the graft-versus-leukemia effect and peptide vaccine-based immunotherapy

(2008) A S M Yong et al.   LEUKEMIA

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

(2008) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA