Journal
CANCER CELL
Volume 19, Issue 6, Pages 697-699Publisher
CELL PRESS
DOI: 10.1016/j.ccr.2011.05.022
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Two recent Cancer Cell articles report the discovery of reciprocal feedback regulation between androgenic and PTEN loss/PI3K-AKT signaling in prostate cancer. Both studies link endocrine regulation with a common oncogenic pathway, which led to the development of a combination therapeutic approach with immediate application in prostate cancer.
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