Journal
CANCER CELL
Volume 14, Issue 2, Pages 105-107Publisher
CELL PRESS
DOI: 10.1016/j.ccr.2008.07.011
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In this issue of Cancer Cell, Yang et al. (2008) and Schuller et al. (2008) show that Hedgehog activation in either multipotent neural stem cells or developmentally restricted progenitors causes only medulloblastomas to form. These data suggest that some stem cell-derived tumors must commit to a specific lineage in order to grow.
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