Differentiation of glioblastoma multiforme stem-like cells leads to downregulation of EGFR and EGFRvIII and decreased tumorigenic and stem-like cell potential

Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures

(2013) Karina Kristoffersen et al.   CANCER BIOLOGY & THERAPY

A Minority Subpopulation of CD133+/EGFRvIII+/EGFR−Cells Acquires Stemness and Contributes to Gefitinib Resistance

(2013) Xu-Jie Liu et al.   CNS Neuroscience & Therapeutics

Epidermal Growth Factor Receptor Variant III Contributes to Cancer Stem Cell Phenotypes in Invasive Breast Carcinoma

(2012) C. A. Del Vecchio et al.   CANCER RESEARCH

Maintenance of EGFR and EGFRvIII expressions in an in vivo and in vitro model of human glioblastoma multiforme

(2011) Marie-Thérése Stockhausen et al.   EXPERIMENTAL CELL RESEARCH

Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition

(2011) M Ying et al.   ONCOGENE

Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells

(2011) Justin D. Lathia et al.   PLoS One

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis

(2010) S. Mazzoleni et al.   CANCER RESEARCH

Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells

(2010) B. Campos et al.   CLINICAL CANCER RESEARCH

Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal

(2010) Adan Aguirre et al.   NATURE

Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells

(2009) Angel Ayuso-Sacido et al.   JOURNAL OF NEURO-ONCOLOGY

Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution

(2009) S G M Piccirillo et al.   ONCOGENE

Epidermal Growth Factor Plays a Crucial Role in Mitogenic Regulation of Human Brain Tumor Stem Cells

(2008) Akio Soeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brain Tumor Stem Cells: Bringing Order to the Chaos of Brain Cancer

(2008) Peter B. Dirks   JOURNAL OF CLINICAL ONCOLOGY

Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas

(2008) Kyeung Min Joo et al.   LABORATORY INVESTIGATION