Antagonism of adenosine A2A receptor expressed by lung adenocarcinoma tumor cells and cancer associated fibroblasts inhibits their growth

Altered metabolism in cancer

(2012) Jason W Locasale et al.   BMC BIOLOGY

CD73-Deficient Mice Are Resistant to Carcinogenesis

(2012) J. Stagg et al.   CANCER RESEARCH

Multiple Analyses of G-Protein Coupled Receptor (GPCR) Expression in the Development of Gefitinib-Resistance in Transforming Non-Small-Cell Lung Cancer

(2012) Naoko Kuzumaki et al.   PLoS One

Impaired A2A adenosine receptor/nitric oxide/VEGF signaling pathway in fetal endothelium during late- and early-onset preeclampsia

(2012) Carlos Escudero et al.   Purinergic Signalling

Pirfenidone inhibits TGF-β1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells

(2012) Keiko Hisatomi et al.   BMC Pulmonary Medicine

Usefulness of Olanzapine as an Adjunct to Opioid Treatment and for the Treatment of Neuropathic Pain

(2011) Kazuhiro Torigoe et al.   ANESTHESIOLOGY

Istradefylline for the treatment of Parkinson's disease

(2011) Ariane Park et al.   EXPERT OPINION ON PHARMACOTHERAPY

Cancer-associated fibroblasts correlate with poor prognosis in rectal cancer after chemoradiotherapy

(2011) Saigusa   INTERNATIONAL JOURNAL OF ONCOLOGY

Subdiaphragmatic vagotomy increases the sensitivity of lumbar Aδ primary afferent neurons along with voltage-dependent potassium channels in rats

(2011) Sadayoshi Furuta et al.   SYNAPSE

Adenosine receptors and cancer

(2010) Stefania Gessi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression

(2010) D. Jin et al.   CANCER RESEARCH

Tumour-associated fibroblasts and mesenchymal stem cells: more similarities than differences

(2010) Virgil Paunescu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Role of Tumor Stroma in Cancer Progression and Prognosis: Emphasis on Carcinoma-Associated Fibroblasts and Non-small Cell Lung Cancer

(2010) Roy M. Bremnes et al.   Journal of Thoracic Oncology

Extracellular adenosine triphosphate and adenosine in cancer

(2010) J Stagg et al.   ONCOGENE

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

(2010) J. Stagg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein- 

(2010) M. Kraman et al.   SCIENCE

Pirfenidone inhibits carbon tetrachloride- and albumin complex-induced liver fibrosis in rodents by preventing activation of hepatic stellate cells

(2009) Xin-Yan Zhao et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Cancer-associated fibroblasts and tumor growth – bystanders turning into key players

(2009) Arne Östman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Adenosine A2A receptor is a unique angiogenic target of HIF-2  in pulmonary endothelial cells

(2009) A. Ahmad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pirfenidone Inhibits T-Cell Activation, Proliferation, Cytokine and Chemokine Production, and Host Alloresponses

(2009) Gary A. Visner et al.   TRANSPLANTATION

Pharmacological Blockade of A2A Receptors Prevents Dermal Fibrosis in a Model of Elevated Tissue Adenosine

(2008) Patricia Fernández et al.   AMERICAN JOURNAL OF PATHOLOGY

The Adenosine A2a Receptor Inhibits Matrix-Induced Inflammation in a Novel Fashion

(2008) Kara A. Scheibner et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The role of endothelial-to-mesenchymal transition in cancer progression

(2008) S Potenta et al.   BRITISH JOURNAL OF CANCER