Isocitrate dehydrogenase 1R132H mutation in microglia/macrophages in gliomas

Hypothesis: Are Neoplastic Macrophages/Microglia Present in Glioblastoma Multiforme?

(2011) Leanne C Huysentruyt et al.   ASN Neuro

Cell proliferation and migration are mutually exclusive cellular phenomena in vivo: Implications for cancer therapeutic strategies

(2011) Ping-Pin Zheng et al.   CELL CYCLE

Microglia/macrophages promote glioma progression

(2010) Haiyan Zhai et al.   GLIA

Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations

(2010) Stefan Gross et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Glioma cancer stem cells induce immunosuppressive macrophages/microglia

(2010) Adam Wu et al.   NEURO-ONCOLOGY

Microglia

(2010) Julia Kofler et al.   TOXICOLOGIC PATHOLOGY

IDH mutations in glioma and acute myeloid leukemia

(2010) Lenny Dang et al.   TRENDS IN MOLECULAR MEDICINE

Monoclonal antibody specific for IDH1 R132H mutation

(2009) David Capper et al.   ACTA NEUROPATHOLOGICA

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE