HO-3867, a STAT3 inhibitor induces apoptosis by inactivation of STAT3 activity in BRCA1-mutated ovarian cancer cells

Identification of BRCA1-deficient ovarian cancers

(2011) ANNE-BINE SKYTTE et al.   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA

Cellular uptake, retention and bioabsorption of HO-3867, a fluorinated curcumin analog with potential antitumor properties

(2011) Alex Dayton et al.   CANCER BIOLOGY & THERAPY

HO-3867, a curcumin analog, sensitizes cisplatin-resistant ovarian carcinoma, leading to therapeutic synergy through STAT3 inhibition

(2011) Karuppaiyah Selvendiran et al.   CANCER BIOLOGY & THERAPY

BRCA1/2testing: uptake, phenocopies, and strategies to improve detection rates in initially negative families

(2011) C Fischer et al.   CLINICAL GENETICS

PARP Inhibitors in BRCA Gene-Mutated Ovarian Cancer and Beyond

(2011) Susana Banerjee et al.   Current Oncology Reports

Concomitant activation of the JAK/STAT3 and ERK1/2 signaling is involved in leptin-mediated proliferation of renal cell carcinoma Caki-2 cells

(2010) Lei Li et al.   CANCER BIOLOGY & THERAPY

Loss of BRCA1 function increases the antitumor activity of cisplatin against human breast cancer xenografts in vivo

(2010) Pierfrancesco Tassone et al.   CANCER BIOLOGY & THERAPY

Safe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluorodiarylidenyl piperidones: Differential cytotoxicity in healthy and cancer cells

(2010) Karuppaiyah Selvendiran et al.   FREE RADICAL BIOLOGY AND MEDICINE

SGO White Paper on Ovarian Cancer: Etiology, Screening and Surveillance

(2010) John O. Schorge et al.   GYNECOLOGIC ONCOLOGY

HO-3867, a Synthetic Compound, Inhibits the Migration and Invasion of Ovarian Carcinoma Cells through Downregulation of Fatty Acid Synthase and Focal Adhesion Kinase

(2010) K. Selvendiran et al.   MOLECULAR CANCER RESEARCH

Anticancer Efficacy of a Difluorodiarylidenyl Piperidone (HO-3867) in Human Ovarian Cancer Cells and Tumor Xenografts

(2010) K. Selvendiran et al.   MOLECULAR CANCER THERAPEUTICS

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Effect ofBRCA1/2Mutations on Long-Term Survival of Patients With Invasive Ovarian Cancer: The National Israeli Study of Ovarian Cancer

(2007) Angela Chetrit et al.   JOURNAL OF CLINICAL ONCOLOGY