Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts

Induction of autophagic cell death by a novel molecule Is increased by hypoxia

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Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation

(2010) Margaret A. Park et al.   CANCER BIOLOGY & THERAPY

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Chronic Hepatitis B and Hepatocellular Carcinoma

(2010) Amy C. McClune et al.   Clinics in Liver Disease

Doxorubicin Plus Sorafenib vs Doxorubicin Alone in Patients With Advanced Hepatocellular Carcinoma

(2010) Ghassan K. Abou-Alfa et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The BCL-2 Protein BAK Is Required for Long-chain Ceramide Generation during Apoptosis

(2010) Leah J. Siskind et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatocellular Carcinoma: Consensus Recommendations of the National Cancer Institute Clinical Trials Planning Meeting

(2010) Melanie B. Thomas et al.   JOURNAL OF CLINICAL ONCOLOGY

Economic evaluation of sorafenib in unresectable hepatocellular carcinoma

(2010) Brian I. Carr et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2

(2010) K. J. French et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A Novel Sphingosine Kinase Inhibitor Induces Autophagy in Tumor Cells

(2010) V. Beljanski et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Sorafenib in Metastatic Renal Cell Carcinoma With Sarcomatoid Differentiation

(2010) Murat Lekili et al.   Journal of the Chinese Medical Association

Sorafenib in Patients with Advanced Non-small Cell Lung Cancer that Harbor K-Ras Mutations: A Brief Report

(2010) Egbert F. Smit et al.   Journal of Thoracic Oncology

Management of advanced hepatocellular carcinoma in the era of targeted therapy

(2010) Thomas Yau et al.   LIVER INTERNATIONAL

The role of signaling pathways in the development and treatment of hepatocellular carcinoma

(2010) S Whittaker et al.   ONCOGENE

Liver Functional Reserve Estimation: State of the Art and Relevance to Local Treatments

(2010) Fotini Manizate et al.   ONCOLOGY

Molecular facets of sphingolipids: Mediators of diseases

(2009) Fatma Betul Kavun Ozbayraktar et al.   Biotechnology Journal

Sphingolipids as Determinants of Apoptosis and Chemoresistance in the MCF-7 Cell Model System

(2009) William D. Meacham et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Ceramide metabolism determines glioma cell resistance to chemotherapy

(2009) Claudia Alexandra Dumitru et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Quantitative analysis of sphingosine-1-phosphate by HPLC after napthalene-2,3-dicarboxaldehyde (NDA) derivatization

(2009) Xingxuan He et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Commentary: Sorafenib Use in Patients with Advanced Hepatocellular Carcinoma and Underlying Child-Pugh B Cirrhosis--Evidence and Controversy

(2009) A. X. Zhu et al.   ONCOLOGIST

Systemic Therapy for Hepatocellular Carcinoma: Cytotoxic Chemotherapy, Targeted Therapy and Immunotherapy

(2008) Melanie B. Thomas et al.   ANNALS OF SURGICAL ONCOLOGY

Bioactive sphingolipids: metabolism and function

(2008) Nana Bartke et al.   JOURNAL OF LIPID RESEARCH

Growth factor receptors and related signalling pathways as targets for novel treatment strategies of hepatocellular cancer

(2008) Michael Höpfner et al.   WORLD JOURNAL OF GASTROENTEROLOGY