Pleiotropic effects of moonlighting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in cancer progression, invasiveness, and metastases

Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression

(2016) Kaiyan Liu et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Role of Apoptosis Signal-regulating Kinase 1 (ASK1) as an Activator of the GAPDH-Siah1 Stress-Signaling Cascade

(2014) Carlos A. Tristan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin’s B lymphomas via NF-κB-dependent induction of HIF-1α

(2014) J Chiche et al.   LEUKEMIA

GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death

(2013) M A Jacquin et al.   CELL DEATH AND DIFFERENTIATION

Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells

(2011) Yasuki Higashimura et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Akt2 Kinase Suppresses Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH)-mediated Apoptosis in Ovarian Cancer Cells via Phosphorylating GAPDH at Threonine 237 and Decreasing Its Nuclear Translocation

(2011) Qiaojia Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glyceraldehyde-3-phosphate dehydrogenase interacts with phosphorylated Akt resulting from increased blood glucose in rat cardiac muscle

(2010) Takeshi Baba et al.   FEBS LETTERS

Glyceraldehyde-3-phosphate dehydrogenase expression is altered by hypoxia in melanoma cells and primary human melanocytes

(2010) Courtney F. Silverthorn et al.   MELANOMA RESEARCH

GAPDH mediates nitrosylation of nuclear proteins

(2010) Michael D. Kornberg et al.   NATURE CELL BIOLOGY

The Multifunctional Protein Glyceraldehyde-3-Phosphate Dehydrogenase Is Both Regulated and Controls Colony-Stimulating Factor-1 Messenger RNA Stability in Ovarian Cancer

(2008) Y. Zhou et al.   MOLECULAR CANCER RESEARCH