Mimicking breast cancer-induced bone metastasis in vivo: current transplantation models and advanced humanized strategies

A tissue-engineered humanized xenograft model of human breast cancer metastasis to bone

(2014) L. Thibaudeau et al.   Disease Models & Mechanisms

Effect of culture conditions and calcium phosphate coating on ectopic bone formation

(2013) Cédryck Vaquette et al.   BIOMATERIALS

The perivascular niche regulates breast tumour dormancy

(2013) Cyrus M. Ghajar et al.   NATURE CELL BIOLOGY

Novel mouse mammary cell lines for in vivo bioluminescence imaging (BLI) of bone metastasis

(2012) Celeste Bolin et al.   BIOLOGICAL PROCEDURES ONLINE

Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape

(2012) Bradley N Bidwell et al.   NATURE MEDICINE

Multiorgan Metastasis of Human HER-2+ Breast Cancer in Rag2−/−;Il2rg−/− Mice and Treatment with PI3K Inhibitor

(2012) Patrizia Nanni et al.   PLoS One

Bone metastasis in a novel breast cancer mouse model containing human breast and human bone

(2011) Tian-Song Xia et al.   BREAST CANCER RESEARCH AND TREATMENT

In vivo animal models of spinal metastasis

(2011) Davina Cossigny et al.   CANCER AND METASTASIS REVIEWS

Ovine cortical osteoblasts outperform bone marrow cells in an ectopic bone assay

(2011) J. C. Reichert et al.   Journal of Tissue Engineering and Regenerative Medicine

Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes

(2011) Yoko S DeRose et al.   NATURE MEDICINE

The Reaction of Bone to Tumor Growth From Human Breast Cancer Cells in a Rat Spine Single Metastasis Model

(2011) Haixiang Liang et al.   SPINE

Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts

(2010) Charlotta J Olsen et al.   BMC CANCER

Vitamin D deficiency promotes growth of MCF-7 human breast cancer in a rodent model of osteosclerotic bone metastasis

(2010) Li Laine Ooi et al.   BONE

Insulin like growth factor binding protein-7 reduces growth of human breast cancer cells and xenografted tumors

(2010) Y. Amemiya et al.   BREAST CANCER RESEARCH AND TREATMENT

A human bone NOD/SCID mouse model to distinguish metastatic potential in primary breast cancers

(2010) Pearl Lam et al.   CANCER BIOLOGY & THERAPY

Human Bone Marrow-Derived MSCs Can Home to Orthotopic Breast Cancer Tumors and Promote Bone Metastasis

(2010) R. H. Goldstein et al.   CANCER RESEARCH

Vitamin D Deficiency Promotes Human Breast Cancer Growth in a Murine Model of Bone Metastasis

(2010) L. L. Ooi et al.   CANCER RESEARCH

Biomaterials offer cancer research the third dimension

(2010) Dietmar W. Hutmacher   NATURE MATERIALS

A novel orthotopic and metastatic mouse model of breast cancer in human mammary microenvironment

(2009) Jue Wang et al.   BREAST CANCER RESEARCH AND TREATMENT

Inhibition of Rho-Associated Kinase Signaling Prevents Breast Cancer Metastasis to Human Bone

(2009) S. Liu et al.   CANCER RESEARCH

Enhanced expression and shedding of receptor activator of NF-κB ligand during tumor–bone interaction potentiates mammary tumor-induced osteolysis

(2009) Kalyan C. Nannuru et al.   CLINICAL & EXPERIMENTAL METASTASIS

Osteotropic cancers: From primary tumor to bone

(2008) Jeroen T. Buijs et al.   CANCER LETTERS

An Immunotolerant HER-2/neu Transgenic Mouse Model of Metastatic Breast Cancer

(2008) H. Song et al.   CLINICAL CANCER RESEARCH

Denosumab, a Fully Human Monoclonal Antibody to RANKL, Inhibits Bone Resorption and Increases BMD in Knock-In Mice That Express Chimeric (Murine/Human) RANKL*

(2008) Paul J Kostenuik et al.   JOURNAL OF BONE AND MINERAL RESEARCH