Suppression of tumor and metastasis progression through the scaffolding functions of SSeCKS/Gravin/AKAP12

AKAP12 regulates vascular integrity in zebrafish

(2012) Hyouk-Bum Kwon et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

A genome-wide association study identifies novel loci associated with susceptibility to chronic myeloid leukemia

(2011) D. H. Kim et al.   BLOOD

Replication and Functional Genomic Analyses of the Breast Cancer Susceptibility Locus at 6q25.1 Generalize Its Importance in Women of Chinese, Japanese, and European Ancestry

(2011) Qiuyin Cai et al.   CANCER RESEARCH

Control of Protein Kinase C Activity, Phorbol Ester-induced Cytoskeletal Remodeling, and Cell Survival Signals by the Scaffolding Protein SSeCKS/GRAVIN/AKAP12

(2011) Li-Wu Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of the a kinase anchor protein 12 (AKAP12) gene as a candidate tumor suppressor of hepatocellular carcinoma

(2011) M Hayashi et al.   JOURNAL OF SURGICAL ONCOLOGY

Temporal profile of Src, SSeCKS, and angiogenic factors after focal cerebral ischemia: Correlations with angiogenesis and cerebral edema

(2011) Likun Zan et al.   NEUROCHEMISTRY INTERNATIONAL

Retinoid-Induced Expression and Activity of an Immediate Early Tumor Suppressor Gene in Vascular Smooth Muscle Cells

(2011) Jeffrey W. Streb et al.   PLoS One

Re-Expression of AKAP12 Inhibits Progression and Metastasis Potential of Colorectal Carcinoma In Vivo and In Vitro

(2011) Weiwei Liu et al.   PLoS One

SERPINB5 and AKAP12-- Expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma

(2010) Wolf A Mardin et al.   BMC CANCER

1,25 dihydroxyvitamin D-mediated orchestration of anticancer, transcript-level effects in the immortalized, non-transformed prostate epithelial cell line, RWPE1

(2010) Pavlo L Kovalenko et al.   BMC GENOMICS

Quantitative assessment of AKAP12 promoter methylation in colorectal cancer using methylation-sensitive high resolution melting: Correlation with Duke's stage

(2010) Weiwei Liu et al.   CANCER BIOLOGY & THERAPY

Rb-dependent cellular senescence, multinucleation and susceptibility to oncogenic transformation through PKC scaffolding by SSeCKS/AKAP12

(2010) Shin Akakura et al.   CELL CYCLE

Examination of AKAP12 promoter methylation in skin cancer using methylation-sensitive high-resolution melting analysis

(2010) W. Wu et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Role for transcription factor TFII-I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src

(2010) Yahao Bu et al.   INTERNATIONAL JOURNAL OF CANCER

Carcinogen-induced squamous papillomas and oncogenic progression in the absence of the SSeCKS/AKAP12 metastasis suppressor correlate with FAK upregulation

(2010) Shin Akakura et al.   INTERNATIONAL JOURNAL OF CANCER

Thioredoxin 1 enhances neovascularization and reduces ventricular remodeling during chronic myocardial infarction: A study using thioredoxin 1 transgenic mice

(2010) Ram Sudheer Adluri et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Proteomics of Smad4 regulated transforming growth factor-beta signalling in colon cancer cells

(2010) Naveid Ahmad Ali et al.   Molecular BioSystems

A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus

(2009) Z. Jin et al.   CANCER RESEARCH

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

(2009) H. Harlin et al.   CANCER RESEARCH

Cellular senescence: Its role in tumor suppression and aging

(2009) Naoko Ohtani et al.   CANCER SCIENCE

Gravin dynamics regulates the subcellular distribution of PKA

(2009) Xiaohong Yan et al.   EXPERIMENTAL CELL RESEARCH

Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface

(2009) Hye Shin Lee et al.   FEBS Journal

SSeCKS/Gravin/AKAP12 Inhibits Cancer Cell Invasiveness and Chemotaxis by Suppressing a Protein Kinase C- Raf/MEK/ERK Pathway

(2009) Bing Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential gene expression in normal esophagus and Barrett’s esophagus

(2009) Jacob Wang et al.   JOURNAL OF GASTROENTEROLOGY

Heterogeneous in vitro effects of doxorubicin on gene expression in primary human liposarcoma cultures

(2008) Adrien Daigeler et al.   BMC CANCER

Hypermethylation of the AKAP12 Promoter is a Biomarker of Barrett's-Associated Esophageal Neoplastic Progression

(2008) Z. Jin et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Loss of the ssecks/gravin/akap12 Gene Results in Prostatic Hyperplasia

(2008) S. Akakura et al.   CANCER RESEARCH

Genome-Wide Transcriptional Response to 5-Aza-2'-Deoxycytidine and Trichostatin A in Multiple Myeloma Cells

(2008) G. Heller et al.   CANCER RESEARCH

Promoter Methylation of Genes in and around the Candidate Lung Cancer Susceptibility Locus 6q23-25

(2008) M. Tessema et al.   CANCER RESEARCH

AKAP12 in astrocytes induces barrier functions in human endothelial cells through protein kinase Cζ

(2008) Yoon Kyung Choi et al.   FEBS Journal

Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma

(2008) Vanessa F. Bonazzi et al.   GENES CHROMOSOMES & CANCER

Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells

(2007) Ajay P. Singh et al.   CANCER LETTERS