Using MKK4’s metastasis suppressor function to identify and dissect cancer cell–microenvironment interactions during metastatic colonization

Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (MKK4)-mediated suppression of omental metastatic colonization

(2012) Russell O. Bainer et al.   CLINICAL & EXPERIMENTAL METASTASIS

Fibroblasts in omentum activated by tumor cells promote ovarian cancer growth, adhesion and invasiveness

(2011) J. Cai et al.   CARCINOGENESIS

ERK1/2 and p38α/β Signaling in Tumor Cell Quiescence: Opportunities to Control Dormant Residual Disease

(2011) Maria Soledad Sosa et al.   CLINICAL CANCER RESEARCH

A historical perspective on the role of stroma in the pathogenesis of benign prostatic hyperplasia

(2011) Gerald R. Cunha et al.   DIFFERENTIATION

Building on the foundation of daring hypotheses: Using the MKK4 metastasis suppressor to develop models of dormancy and metastatic colonization

(2011) Matthew T. Knopeke et al.   FEBS LETTERS

MKK4 suppresses metastatic colonization by multiple highly metastatic prostate cancer cell lines through a transient impairment in cell cycle progression

(2011) Russell Z. Szmulewitz et al.   INTERNATIONAL JOURNAL OF CANCER

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

(2011) Kristin M Nieman et al.   NATURE MEDICINE

The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts

(2011) Héctor Peinado et al.   SEMINARS IN CANCER BIOLOGY

In vitro metastatic colonization of human ovarian cancer cells to the omentum

(2010) Shaheena M. Khan et al.   CLINICAL & EXPERIMENTAL METASTASIS

Disseminated and circulating tumor cells: Role in effective cancer management

(2010) Henry Lin et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Tissue architecture and function: dynamic reciprocity via extra- and intra-cellular matrices

(2009) Ren Xu et al.   CANCER AND METASTASIS REVIEWS

Micrometastatic disease and metastatic outgrowth: clinical issues and experimental approaches

(2009) Patricia M McGowan et al.   Future Oncology

Omental immune aggregates and tumor metastasis within the peritoneal cavity

(2009) Elizabeth W. Sorensen et al.   IMMUNOLOGIC RESEARCH

The Omentum: Anatomical, Metabolic, and Surgical Aspects

(2009) Danielle Collins et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Cancer micrometastasis and tumour dormancy 

(2008) HARRIET WIKMAN et al.   APMIS

New paradigms for the function of JNKK1/MKK4 in controlling growth of disseminated cancer cells

(2008) Jennifer L. Taylor et al.   CANCER LETTERS

c-Jun NH2-Terminal Kinase Activating Kinase 1/Mitogen-Activated Protein Kinase Kinase 4-Mediated Inhibition of SKOV3ip.1 Ovarian Cancer Metastasis Involves Growth Arrest and p21 Up-regulation

(2008) T. Lotan et al.   CANCER RESEARCH