RAS mutations affect pattern of metastatic spread and increase propensity for brain metastasis in colorectal cancer

BRAF mutation predicts for poor outcomes after metastasectomy in patients with metastatic colorectal cancer

(2014) Rona Yaeger et al.   CANCER

KRASmutation influences recurrence patterns in patients undergoing hepatic resection of colorectal metastases

(2014) Nancy E. Kemeny et al.   CANCER

Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH

(2014) Jelena Urosevic et al.   NATURE CELL BIOLOGY

RAS Mutation Status Predicts Survival and Patterns of Recurrence in Patients Undergoing Hepatectomy for Colorectal Liver Metastases

(2013) Jean-Nicolas Vauthey et al.   ANNALS OF SURGERY

Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases

(2013) Georgios Karagkounis et al.   CANCER

PIK3CA, BRAF , and PTEN Status and Benefit from Cetuximab in the Treatment of Advanced Colorectal Cancer—Results from NCIC CTG/AGITG CO.17

(2013) Christos S. Karapetis et al.   CLINICAL CANCER RESEARCH

Predictive and Prognostic Analysis of PIK3CA Mutation in Stage III Colon Cancer Intergroup Trial

(2013) Shuji Ogino et al.   JNCI-Journal of the National Cancer Institute

Specific Mutations in KRAS Codons 12 and 13, and Patient Prognosis in 1075 BRAF Wild-Type Colorectal Cancers

(2012) Y. Imamura et al.   CLINICAL CANCER RESEARCH

Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review

(2012) X. Liao et al.   CLINICAL CANCER RESEARCH

Clinical features and course of brain metastases in colorectal cancer: an experience from a single institution

(2012) K. Damiens et al.   Current Oncology

Cryptococcus neoformansActivates RhoGTPase Proteins Followed by Protein Kinase C, Focal Adhesion Kinase, and Ezrin to Promote Traversal across the Blood-Brain Barrier

(2012) Jong-Chul Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative Genomic Analysis of Primary Versus Metastatic Colorectal Carcinomas

(2012) Efsevia Vakiani et al.   JOURNAL OF CLINICAL ONCOLOGY

Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer

(2011) Ben Tran et al.   CANCER

KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer

(2011) J. Tie et al.   CLINICAL CANCER RESEARCH

Oncogenic PIK3CA mutations in colorectal cancers and polyps

(2011) Vicki L.J. Whitehall et al.   INTERNATIONAL JOURNAL OF CANCER

Detection of KRAS and BRAF Mutations in Colorectal Carcinoma

(2011) Maria Arcila et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Ras-Induced and Extracellular Signal-Regulated Kinase 1 and 2 Phosphorylation-Dependent Isomerization of Protein Tyrosine Phosphatase (PTP)-PEST by PIN1 Promotes FAK Dephosphorylation by PTP-PEST

(2011) Y. Zheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer

(2010) M. Janakiraman et al.   CANCER RESEARCH

Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab

(2010) Jolien Tol et al.   EUROPEAN JOURNAL OF CANCER

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

(2010) Wendy De Roock et al.   LANCET ONCOLOGY

Does colon cancer ever metastasize to bone first? a temporal analysis of colorectal cancer progression

(2009) Eira S Roth et al.   BMC CANCER

PIK3CAMutation Is Associated With Poor Prognosis Among Patients With Curatively Resected Colon Cancer

(2009) Shuji Ogino et al.   JOURNAL OF CLINICAL ONCOLOGY

FAK Phosphorylation by ERK Primes Ras-Induced Tyrosine Dephosphorylation of FAK Mediated by PIN1 and PTP-PEST

(2009) Yanhua Zheng et al.   MOLECULAR CELL

Class I PI3K in oncogenic cellular transformation

(2008) L Zhao et al.   ONCOGENE