What is the best treatment for patients with human papillomavirus-positive and -negative oropharyngeal cancer?

Molecular profile of head and neck squamous cell carcinomas bearing p16 high phenotype

(2013) T. Rampias et al.   ANNALS OF ONCOLOGY

Incidence and pattern of second primary malignancies in patients with index oropharyngeal cancers versus index nonoropharyngeal head and neck cancers

(2013) Samuel J. Gan et al.   CANCER

Evidence for a Role of the PD-1:PD-L1 Pathway in Immune Resistance of HPV-Associated Head and Neck Squamous Cell Carcinoma

(2013) S. Lyford-Pike et al.   CANCER RESEARCH

Deintensification Candidate Subgroups in Human Papillomavirus–Related Oropharyngeal Cancer According to Minimal Risk of Distant Metastasis

(2013) Brian O'Sullivan et al.   JOURNAL OF CLINICAL ONCOLOGY

Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial

(2013) Jan B Vermorken et al.   LANCET ONCOLOGY

OP041

(2013) Jan B. Vermorken et al.   ORAL ONCOLOGY

A phase II trial of dacomitinib, an oral pan-human EGF receptor (HER) inhibitor, as first-line treatment in recurrent and/or metastatic squamous-cell carcinoma of the head and neck

(2012) A. R. Abdul Razak et al.   ANNALS OF ONCOLOGY

Randomised Phase II study of oral lapatinib combined with chemoradiotherapy in patients with advanced squamous cell carcinoma of the head and neck: Rationale for future randomised trials in human papilloma virus-negative disease

(2012) Kevin Harrington et al.   EUROPEAN JOURNAL OF CANCER

A novel RT-PCR method for quantification of human papillomavirus transcripts in archived tissues and its application in oropharyngeal cancer prognosis

(2012) Ge Gao et al.   INTERNATIONAL JOURNAL OF CANCER

Prevalence of Oral HPV Infection in the United States, 2009-2010

(2012) Maura L. Gillison et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Tobacco Smoking and Increased Risk of Death and Progression for Patients With p16-Positive and p16-Negative Oropharyngeal Cancer

(2012) Maura L. Gillison et al.   JOURNAL OF CLINICAL ONCOLOGY

Long-Term Results of RTOG 91-11: A Comparison of Three Nonsurgical Treatment Strategies to Preserve the Larynx in Patients With Locally Advanced Larynx Cancer

(2012) Arlene A. Forastiere et al.   JOURNAL OF CLINICAL ONCOLOGY

Differential response rates to irradiation among patients with human papillomavirus positive and negative oropharyngeal cancer

(2012) Allen M. Chen et al.   LARYNGOSCOPE

Partial p16 staining in oropharyngeal squamous cell carcinoma: extent and pattern correlate with human papillomavirus RNA status

(2012) James S Lewis et al.   MODERN PATHOLOGY

Molecular phenotype predicts sensitivity of squamous cell carcinoma of the head and neck to epidermal growth factor receptor inhibition

(2012) Natalie R. Young et al.   Molecular Oncology

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Survival and human papillomavirus in oropharynx cancer in TAX 324: a subset analysis from an international phase III trial

(2011) M. R. Posner et al.   ANNALS OF ONCOLOGY

Anatomic sites at elevated risk of second primary cancer after an index head and neck cancer

(2011) Luc G. T. Morris et al.   CANCER CAUSES & CONTROL

Relationship between Epidermal Growth Factor Receptor Status, p16INK4A, and Outcome in Head and Neck Squamous Cell Carcinoma

(2011) R. J. Young et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer

(2011) J. D. Sun et al.   CLINICAL CANCER RESEARCH

p16 expression as a surrogate marker for HPV-related oropharyngeal carcinoma: A guide for interpretative relevance and consistency

(2011) Adel K. El-Naggar et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States

(2011) Anil K. Chaturvedi et al.   JOURNAL OF CLINICAL ONCOLOGY

Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

The influence of HPV-associated p16-expression on accelerated fractionated radiotherapy in head and neck cancer: Evaluation of the randomised DAHANCA 6&7 trial

(2011) Pernille Lassen et al.   RADIOTHERAPY AND ONCOLOGY

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck

(2011) Nicole G Chau et al.   Head and Neck Optical Diagnostics Society

Concomitant chemoradiation versus radical radiotherapy in advanced squamous cell carcinoma of oropharynx and nasopharynx using weekly cisplatin: a phase II randomized trial

(2010) A. Sharma et al.   ANNALS OF ONCOLOGY

Pharmacokinetic/Pharmacodynamic Modeling Identifies SN30000 and SN29751 as Tirapazamine Analogues with Improved Tissue Penetration and Hypoxic Cell Killing in Tumors

(2010) K. O. Hicks et al.   CLINICAL CANCER RESEARCH

Tobacco Use in Human Papillomavirus-Positive Advanced Oropharynx Cancer Patients Related to Increased Risk of Distant Metastases and Tumor Recurrence

(2010) J. H. Maxwell et al.   CLINICAL CANCER RESEARCH

Atypical Clinical Behavior of p16-Confirmed HPV-Related Oropharyngeal Squamous Cell Carcinoma Treated With Radical Radiotherapy

(2010) Shao Hui Huang et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Prognostic Significance of p16INK4Aand Human Papillomavirus in Patients With Oropharyngeal Cancer Treated on TROG 02.02 Phase III Trial

(2010) Danny Rischin et al.   JOURNAL OF CLINICAL ONCOLOGY

Intensity-Modulated Chemoradiotherapy Aiming to Reduce Dysphagia in Patients With Oropharyngeal Cancer: Clinical and Functional Results

(2010) Felix Y. Feng et al.   JOURNAL OF CLINICAL ONCOLOGY

Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer

(2010) K. Kian Ang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumour boards/multidisciplinary head and neck cancer meetings: are they of value to patients, treating staff or a political additional drain on healthcare resources?

(2009) Thomas Westin et al.   Current Opinion in Otolaryngology & Head and Neck Surgery

Effect of HPV-Associated p16INK4A Expression on Response to Radiotherapy and Survival in Squamous Cell Carcinoma of the Head and Neck

(2009) Pernille Lassen et al.   JOURNAL OF CLINICAL ONCOLOGY

Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival

(2009) James A Bonner et al.   LANCET ONCOLOGY

Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients

(2009) Jean-Pierre Pignon et al.   RADIOTHERAPY AND ONCOLOGY

HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer

(2009) Pernille Lassen et al.   RADIOTHERAPY AND ONCOLOGY

Cystic lymph node metastasis in patients with head and neck cancer: An HPV-associated phenomenon

(2008) David Goldenberg et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas

(2008) Harriët C. Hafkamp et al.   INTERNATIONAL JOURNAL OF CANCER

Incidence Trends for Human Papillomavirus–Related and –Unrelated Oral Squamous Cell Carcinomas in the United States

(2008) Anil K. Chaturvedi et al.   JOURNAL OF CLINICAL ONCOLOGY

EGFR, p16, HPV Titer, Bcl-xL and p53, Sex, and Smoking As Indicators of Response to Therapy and Survival in Oropharyngeal Cancer

(2008) Bhavna Kumar et al.   JOURNAL OF CLINICAL ONCOLOGY

Improved Survival of Patients With Human Papillomavirus-Positive Head and Neck Squamous Cell Carcinoma in a Prospective Clinical Trial

(2008) C. Fakhry et al.   JNCI-Journal of the National Cancer Institute