Article
Medicine, Research & Experimental
Xiawei Li, Litao Yang, Zheping Yuan, Jianyao Lou, Yiqun Fan, Aiguang Shi, Junjie Huang, Mingchen Zhao, Yulian Wu
Summary: Machine learning models were developed to predict the risk of relapse in PDAC patients after radical resection, with random forest outperforming other methods in training set, and support vector machine and k neighbor algorithm showing better performance in validation set. The comprehensive models will guide personalized surveillance programs after surgery.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Oncology
Zhenkai Luo, Binbin Jiao, Tao Huang, Hang Zhao, Weifeng He, Yuxuan Bo, Zhenshan Ding, Guan Zhang
Summary: This study aimed to establish and validate nomograms to predict the probability of intravesical recurrence after radical nephroureterectomy for upper urinary tract epithelial carcinoma. Clinical data of 528 patients were collected and analyzed using LASSO regression and Cox regression analysis to build a predictive nomogram model. The model demonstrated excellent discriminatory performance and was validated in an external cohort.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Oncology
Guangmeng Guo, Zhengqing Lei, Xuewu Tang, Weihu Ma, Anfeng Si, Pinghua Yang, Qi Li, Zhimin Geng, Jiahua Zhou, Zhangjun Cheng
Summary: The study validated and compared the predictive ability of the ALBI model with other liver functional reserve models for posthepatectomy liver failure in patients with hepatocellular carcinoma. The ALBI model showed the highest AUC for predicting PHLF and had good predictive performance in both cirrhotic and non-cirrhotic patients.
Article
Surgery
Kim Bunthof, Khalid Saboerali, Jacqueline Van De Wetering, Azam Nurmohamed, Frederike Bemelman, Arjan Van Zuilen, Jan Van Den Brand, Marije Baas, Luuk Hilbrands
Summary: This study aimed to validate a previously established prediction model for graft intolerance syndrome in an independent cohort. The validation cohort consisted of patients with late kidney graft failure between 2008 and 2018. The original model, which included donor age, graft survival, and number of acute rejections, performed poorly in the validation cohort. However, after retraining the model using recipient age at graft failure instead of donor age, it showed moderate performance in both the development and validation cohorts.
TRANSPLANT INTERNATIONAL
(2023)
Article
Cardiac & Cardiovascular Systems
Li Shen, Brian L. Claggett, Pardeep S. Jhund, William T. Abraham, Akshay Suvas Desai, Kenneth Dickstein, Jianjian Gong, Lars V. Kober, Marty P. Lefkowitz, Jean L. Rouleau, Victor C. Shi, Karl Swedberg, Michael R. Zile, Scott D. Solomon, John J. V. McMurray
Summary: This study developed and validated models that can predict SD and PFD separately in HFrEF patients, helping clinicians and patients consider therapies targeted at these modes of death.
CLINICAL RESEARCH IN CARDIOLOGY
(2021)
Article
Urology & Nephrology
P. Baron, Z. Khene, F. Lannes, G. Pignot, A. S. Bajeot, G. Ploussard, G. Verhoest, A. Gasmi, O. Perrot, M. Roumiguie, K. Mori, G. E. Cacciamani, M. Roupret, F. Bruyere, B. Pradere
Summary: The study confirmed that RC-pentafecta can be used to evaluate the surgical outcomes of RARC patients, with age being an independent predictor of pentafecta achievement and surgeon experience impacting the validation of the criteria.
WORLD JOURNAL OF UROLOGY
(2021)
Article
Critical Care Medicine
Chiang Dung-Hung, Tian Cong, Jiang Zeyu, Ou-Yang Yu-Shan, Lin Yung-Yan
Summary: The study aimed to independently validate the Hemodynamic Stability Index (HSI) in predicting hemodynamic instability in Asian patients. The results showed that the HSI model performed better than single indicators in predicting patients who received hemodynamic interventions, demonstrating its potential utility in critical care settings.
Article
Surgery
Elise A. J. de Savornin Lohman, T. J. J. de Bitter, G. Hannink, M. F. T. Wietsma, E. Vink-Borger, I. D. Nagtegaal, T. J. Hugh, A. J. Gill, N. Bhimani, M. Seyed Ahadi, R. S. van der Post, Philip R. de Reuver
Summary: The study aimed to develop and validate a clinical prediction model for overall survival in patients with nonmetastatic, resected gallbladder cancer (GBC). Data from a Dutch cohort was used for development and an Australian cohort for external validation. The proposed model demonstrated superior discriminatory capacity compared to the AJCC staging system and can be a useful tool for physicians and patients.
Article
Clinical Neurology
Dillon Vyas, James Booker, Daisy Smith, Yahia Z. Al-Tamimi
Summary: This study externally validated 4 scoring models for predicting ventriculoperitoneal shunt insertion after aneurysmal subarachnoid hemorrhage, with scoring model 4 being the most effective. However, the applicability of scoring model 4 is limited in modern practice, highlighting the need for a new scoring model.
WORLD NEUROSURGERY
(2021)
Article
Obstetrics & Gynecology
E. Christodoulou, S. Bobdiwala, C. Kyriacou, J. Farren, N. Mitchell-Jones, F. Ayim, B. Chohan, O. Abughazza, B. Guruwadahyarhalli, M. Al-Memar, S. Guha, V. Vathanan, D. Gould, C. Stalder, L. Wynants, D. Timmerman, T. Bourne, B. Van Calster
Summary: The study validated the effectiveness of five approaches to predict ectopic pregnancy in pregnancies of unknown location (PUL), and found that the two-step triage strategy (2ST) and M6P performed best in prediction and triage.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Biology
Bartosz Malkiewicz, Kuba Ptaszkowski, Klaudia Knecht, Adam Gurwin, Karol Wilk, Pawel Kielb, Krzysztof Dudek, Romuald Zdrojowy
Summary: The study aimed to validate the performance of the 2012 Briganti nomogram in predicting pelvic lymph node invasion in men who underwent radical prostatectomy, and found that a nomogram-derived cut-off of 7% could reduce the number of lymph node dissections while still detecting patients with lymph node invasion.
Article
Oncology
Jingshu Tong, Wei Jiang, Shuqi Mao, Shengdong Wu, Caide Lu
Summary: This study developed and validated a nomogram for predicting liver metastasis in patients with pancreatic ductal adenocarcinoma (PDAC) after radical resection. The nomogram, based on postoperative CA125 level, tumor characteristics, and invasion degree, showed high accuracy and clinical utility in predicting liver metastasis risk.
FRONTIERS IN ONCOLOGY
(2022)
Article
Gastroenterology & Hepatology
Yun-Long Li, Ding-Ding Zhang, Yang-Yang Xiong, Rui-Feng Wang, Xiao-Mao Gao, Hui Gong, Shi-Cheng Zheng, Dong Wu
Summary: The present study constructed and validated a simple and accurate predictive model for SAP-related ARDS in patients with AP.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Oncology
Zaeem Lone, Prithvi B. Murthy, J. J. Haijing Zhang, Kyle J. Ericson, Lewis Thomas, Abhinav Khanna, Georges-Pascal Haber, Byron H. Lee
Summary: The study compared long-term renal function outcomes between open radical cystectomy and robot-assisted radical cystectomy with extracorporeal or intracorporeal urinary diversion. The results showed that 64% of patients experienced renal function decline, which was influenced by tumor stage, pre-operative eGFR, and development of ureteral strictures.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2021)
Article
Surgery
Wenlong Zhong, Kun Xia, Libo Liu, Sida Cheng, Peng Hong, Wang He, Wen Dong, Hao Liu, Yiming Lai, Han Hao, Cheng Liu, Hongxian Zhang, Xinfei Li, Guangpu Ding, Xuesong Li, Lulin Ma, Liqun Zhou, Tianxin Lin, Jian Huang
Summary: This study compared the long-term oncological outcomes of pelvic organ preserving-radical cystectomy (POPRC) and standard radical cystectomy (SRC) in female patients with bladder cancer. The results showed no significant difference in overall survival between the two surgical methods.
INTERNATIONAL JOURNAL OF SURGERY
(2023)