Tivantinib (ARQ 197), a selective inhibitor of MET, in patients with microphthalmia transcription factor-associated tumors

Phase I results of the randomized, placebo controlled, phase I/II study of the novel oral c-Met inhibitor, ARQ 197, irinotecan (CPT-11), and cetuximab (C) in patients (pts) with wild-type (WT) KRAS metastatic colorectal cancer (mCRC) who have received front-line systemic therapy.

(2017) C. Eng et al.   JOURNAL OF CLINICAL ONCOLOGY

Sunitinib in advanced alveolar soft part sarcoma: evidence of a direct antitumor effect

(2011) S. Stacchiotti et al.   ANNALS OF ONCOLOGY

Phase I Trial of a Selective c-MET Inhibitor ARQ 197 Incorporating Proof of Mechanism Pharmacodynamic Studies

(2011) Timothy A. Yap et al.   JOURNAL OF CLINICAL ONCOLOGY

Treatment of Multidrug Resistant Advanced Alveolar Soft Part Sarcoma With Sunitinib

(2010) Abhimanyu Ghose et al.   AMERICAN JOURNAL OF THERAPEUTICS

Tumor response to sunitinib malate observed in clear-cell sarcoma

(2010) S. Stacchiotti et al.   ANNALS OF ONCOLOGY

Targeted agents in metastatic Xp11 translocation/TFE3 gene fusion renal cell carcinoma (RCC): a report from the Juvenile RCC Network

(2010) G. G. Malouf et al.   ANNALS OF ONCOLOGY

Identification of the Receptor Tyrosine Kinase c-Met and Its Ligand, Hepatocyte Growth Factor, as Therapeutic Targets in Clear Cell Sarcoma

(2010) I. J. Davis et al.   CANCER RESEARCH

Chemotherapy in clear cell sarcoma

(2010) Robin L. Jones et al.   MEDICAL ONCOLOGY

ARQ 197, a Novel and Selective Inhibitor of the Human c-Met Receptor Tyrosine Kinase with Antitumor Activity

(2010) N. Munshi et al.   MOLECULAR CANCER THERAPEUTICS

Response to Sunitinib Malate in Advanced Alveolar Soft Part Sarcoma

(2009) S. Stacchiotti et al.   CLINICAL CANCER RESEARCH

A Case of Adult Metastatic Xp11 Translocation Renal Cell Carcinoma Treated Successfully With Sunitinib

(2009) Toni K. Choueiri et al.   Clinical Genitourinary Cancer

Expression and mutational analysis ofMETin human solid cancers

(2008) Patrick C. Ma et al.   GENES CHROMOSOMES & CANCER