Review
Medicine, General & Internal
Wu Ding, Zaiwei Fan, Yuehuai Xu, Chunshou Wei, Zhian Li, Yingli Lin, Jianming Zhu, Guodong Ruan
Summary: Background: Magnetic resonance imaging (MRI) is more accurate than mammography in screening for breast cancer. Exposure to ionizing radiation from repeated diagnostic X-rays may be a cause of breast cancer. Methods: We conducted a meta-analysis to compare the detection rate of breast cancer by mammography, MRI or both. Results: MRI alone increased the detection rate of breast cancer by 8 compared with mammography alone, and MRI plus mammography increased the detection rate of breast cancer by 1 compared with MRI alone. Subgroup analysis showed that MRI plus mammography had significantly better diagnostic efficacy in breast cancer than MRI alone or mammography alone. Conclusions: Screening with MRI alone might be the best choice for women at high risk of breast cancer.
Article
Oncology
Pabel A. A. Miah, Nakisa Pourkey, Alyssa Marmer, Athanasios Sevdalis, Laura Fiedler, Charles DiMaggio, Linda Pak, Richard Shapiro, Karen Hiotis, Deborah Axelrod, Amber Guth, Freya Schnabel
Summary: This study aimed to analyze our institutional database of high-risk patients and assess the uptake of screening MRI examinations and the results. The results showed that adding MRI screening in our high-risk cohort did not yield a significant number of additional cancer diagnoses. However, breast cancer cases detected in the MRI-screened group were in very early stages, highlighting the benefits of participation in the program.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ritse M. Mann, Alexandra Athanasiou, Pascal A. T. Baltzer, Julia Camps-Herrero, Paola Clauser, Eva M. Fallenberg, Gabor Forrai, Michael H. Fuchsjaeger, Thomas H. Helbich, Fleur Killburn-Toppin, Mihai Lesaru, Pietro Panizza, Federica Pediconi, Ruud M. Pijnappel, Katja Pinker, Francesco Sardanelli, Tamar Sella, Isabelle Thomassin-Naggara, Sophia Zackrisson, Fiona J. Gilbert, Christiane K. Kuhl
Summary: Breast density is an independent risk factor for breast cancer and reduces the effectiveness of mammography. Recent studies show that contrast-enhanced breast MRI can significantly reduce breast cancer mortality and is cost-effective for women with extremely dense breasts. Therefore, the European Society of Breast Imaging (EUSOBI) recommends informing women about their breast density and offering screening breast MRI every 2 to 4 years for women aged 50 to 70 with extremely dense breasts.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Fabian Tollens, Pascal A. T. Baltzer, Matthias Dietzel, Moritz L. Schnitzer, Vincent Schwarze, Wolfgang G. Kunz, Johann Rink, Johannes Ruebenthaler, Matthias F. Froelich, Stefan O. Schoenberg, Clemens G. Kaiser
Summary: This model-based economic study analyzed the cost-effectiveness of full protocol breast MRI (FB-MRI) vs. abbreviated breast MRI (AB-MRI) in screening women with dense breast tissue for breast cancer. The results showed that AB-MRI could be considered cost-effective as long as the costs per examination did not exceed 82% of the cost of a FB-MRI examination.
EUROPEAN RADIOLOGY
(2022)
Review
Oncology
Natsuko Onishi, Masako Kataoka
Summary: This article provides an overview of breast cancer screening guidelines for high-risk women from world-leading specialty societies, discussing personalized screening and various imaging modalities. It also highlights the challenges in high-risk screening and presents the latest information from two large-scale studies.
Article
Oncology
Xuan Shao, Xiaoyan Jin, Zhigang Chen, Zhigang Zhang, Wuzhen Chen, Jingxin Jiang, Zhen Wang, Ying Cui, Wan-Hung Fan, Ke Wang, Xiuyan Yu, Jian Huang
Summary: This study aimed to compare the diagnostic capabilities of circulating tumor cells (CTCs) with imaging modalities in screening for breast cancer in Chinese women. The results showed that CTC tests have comparable diagnostic potency to breast imaging modalities, suggesting their potential as an alternative screening tool for breast cancer.
FRONTIERS IN ONCOLOGY
(2022)
Editorial Material
Biochemistry & Molecular Biology
Nehmat Houssami, Karla Kerlikowske
Summary: AI has the potential to be a new tool in the risk assessment and screening of breast cancer, but its impact on relevant clinical outcomes needs to be prospectively evaluated.
Article
Radiology, Nuclear Medicine & Medical Imaging
Kristen Coffey, Maxine S. Jochelson
Summary: Contrast-enhanced mammography (CEM) is a promising breast imaging technique that provides both anatomical and functional information in detecting breast cancer. It has shown high diagnostic performance, especially in women with dense breasts, and is more cost-effective and accessible than MRI.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Daniel Son, Jordana Phillips, Tejas S. Mehta, Rashmi Mehta, Alexander Brook, Vandana M. Dialani
Summary: The study aimed to gain understanding of patient preferences towards contrast-enhanced imaging such as CEM or MRI for breast cancer screening. An anonymous survey was conducted among patients undergoing screening mammography at a single academic institution. Results showed that a significant proportion of patients with dense breasts and prior CEM/MRI were willing to accept the risks and costs associated with CEM or MRI as a screening exam. Concerns related to aspects of the imaging procedure varied among patients.
ACADEMIC RADIOLOGY
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Raymond J. Acciavatti, Su Hyun Lee, Beatriu Reig, Linda Moy, Emily F. Conant, Despina Kontos, Woo Kyung Moon
Summary: Breast density is an independent risk factor for breast cancer and can be assessed visually using digital mammography and tomosynthesis. In addition to density, textural complexity is also a measure of breast cancer risk. Other screening modalities like breast US and MRI offer independent risk measures as well.
Article
Biochemistry & Molecular Biology
Adam Yala, Peter G. Mikhael, Constance Lehman, Gigin G. Lin, Fredrik Strand, Yung-Liang Wan, Kevin Hughes, Siddharth Satuluru, Thomas Kim, Imon Banerjee, Judy Gichoya, Hari Trivedi, Regina Barzilay
Summary: A reinforcement learning model, Tempo, was introduced to predict risk-based follow-up recommendations in breast cancer screening. The model was trained and validated using large datasets from multiple hospitals. The results showed that Tempo combined with an image-based AI risk model outperformed current clinical practice in terms of simulated early detection. The study demonstrated the potential of AI-based risk models and agile AI-designed screening policies in improving screening programs.
Article
Radiology, Nuclear Medicine & Medical Imaging
Kristen Coffey, Linden B. Dixon, Varadan Sevilimedu, Maxine S. Jochelson, Janice S. Sung
Summary: The study involved 71 women with 81 enhancing CEM lesions who underwent short-term follow-up CEM after MRI reported no correlate. Among the lesions, two cancers were diagnosed during the short-term follow-up period, while the remaining 79 lesions were found to be benign at follow-up. This suggests that follow-up CEM of MRI-occult lesions may be prudent, with a low incidence of cancer detected in a small sample size.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
F. J. Gilbert, S. E. Hickman, G. C. Baxter, I Allajbeu, J. James, C. Carraco, S. Vinnicombe
Summary: Breast cancer screening should be tailored based on individual risk and new technologies can enhance cancer detection rates.
CLINICAL RADIOLOGY
(2021)
Article
Obstetrics & Gynecology
W. Tania Rahman, Mark A. Helvie
Summary: Breast cancer is the most common cancer among females worldwide. Screening mammography and advancements in therapy have significantly reduced mortality. Digital breast tomosynthesis is a new technology that improves the sensitivity and specificity of mammography. High-risk patients should undergo regular screening, and pregnant and lactating women should also receive age-appropriate screening.
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Clemens G. Kaiser, Matthias Dietzel, Tibor Vag, Johannes Rubenthaler, Matthias F. Froelich, Fabian Tollens
Summary: In high-risk breast cancer patients, MR-mammography can be considered a cost-effective alternative to conventional imaging in a yearly screening setting. Specificity may be an important cost driver in settings with yearly screening intervals.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)