Journal
CANCER
Volume 113, Issue 8, Pages 2366-2371Publisher
WILEY
DOI: 10.1002/cncr.23831
Keywords
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Categories
Funding
- Fred Hutchinson Cancer Research Center
- Susan G. Komen for the Cure
- American Society of Clinical Oncology (ASCO)
- US National Cancer Institute, Office of International Affairs (OIA)
- American Cancer Society
- Lance Armstrong Foundation
- US Agency for Healthcare Research and Quality [1 R13 HS017218-01]
- US Centers for Disease Control and Prevention, Division of Cancer Prevention and Control
- American Society of Breast Disease
- Oncology Nursing Society
- US National Cancer Institute, Office of Women's Health (OWH)
- US National Institutes of Health, Office of Research on Women's Health (ORWH)
- National Center for Chronic Disease Prevention and Health Promotion
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In contrast to western high-income nations, the incidence and morality front breast cancer are increasing in most low, and middle-income countries world wide. Current approaches to breast cancer control developed for populations of high-income societies should not be directly transferred without evaluation. A relevant research agenda includes population differences in tumor biology and metabolization of systemic therapies, cultural and psychosocial issues, and operations in healthcare systems. Highest priority should be given to assessments of clinical downstaging and basic systemic treatment effectiveness in low and middle-income populations. Partnerships of existing organizations in high-income nations with those in low and middle -income countries are currently the most feasible sources of research support. Cancer 2008;113(8 suppl):2366-71. (C) 2008 American Cancer Society.
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