Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Noah Lybik, Daniel J. Wale, Ka Kit Wong, Eric Liao, Benjamin L. Viglianti
Summary: Somatostatin receptor imaging, commonly used in neuroendocrine oncology, may have diagnostic utility in various tumors beyond gastroenteropancreatic neuroendocrine neoplasms. In challenging cases, theranostic principles utilizing somatostatin receptor-based therapy could offer potential treatment options.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Endocrinology & Metabolism
Jinci Lu, Liam Chen
Summary: Pituitary sarcoma associated with pituitary adenoma is rare, typically developing around 10.5 years post-radiation; in one case, a 77-year-old male showed tumor progression three years after radiation treatment, revealing a pituitary adenoma with a separate spindle-cell sarcomatous component.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Clinical Neurology
Josh Ma, Peter Gooderham, Ryojo Akagami, Serge Makarenko
Summary: Postoperative diabetes insipidus (DI) after pituitary adenoma resection is correlated with the degree of pituitary gland descent. By quantifying the descent and tension on the pituitary stalk, we can predict the occurrence of postoperative DI.
Article
Clinical Neurology
John W. Rutland, Joshua Loewenstern, Daniel Ranti, Nadejda M. Tsankova, Christopher P. Bellaire, Joshua B. Bederson, Bradley N. Delman, Raj K. Shrivastava, Priti Balchandani
Summary: This study found that high-resolution ADC is a sensitive measure of tumor consistency in pituitary adenomas, suggesting that 7T DWI may hold clinical value in the preoperative workup and surgical management of patients with pituitary macroadenomas.
JOURNAL OF NEUROSURGERY
(2021)
Article
Oncology
Yi-Lin Luo, Fang Gu, Hai-Qing Fan, Jin-Hui Du, Yue Yu, Li-Kun Liu, Xin Liao
Summary: This study explored the diagnostic value of an ectopic posterior pituitary hyperintense signal (EPPHS) in diagnosing pituitary macroadenoma. The formation of EPPHS may be related to injuries to the pituitary stalk.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Tao Xie, Xiaobiao Zhang, Chenghui Qu, Chen Li
Summary: The technique of using a micro retractor for the endoscopic endonasal posterior pseudocapsule resection of pituitary macroadenomas was described, resulting in increased surgical view and facilitating pseudocapsule dissection.
FRONTIERS IN ONCOLOGY
(2021)
Article
Clinical Neurology
Matthew J. Shepard, M. Harrison Snyder, Sauson Soldozy, Leonel L. Ampie, Saul F. Morales-Valero, John A. Jane
Summary: The majority of patients with pituitary apoplexy can be successfully managed without surgical intervention. Patients who underwent early surgery had higher rates of visual impairment and cranial neuropathies at presentation, as well as larger tumor volumes. Visual outcomes were similar between patients with visual deficits who received early surgery and those managed conservatively.
JOURNAL OF NEUROSURGERY
(2021)
Article
Oncology
Muhammad Faraz Raghib, Adnan Salim, Meher Angez, Sanam Mir Ghazi, Shiraz Hashmi, Muhammad Bilal Tariq, Fauzan Hashmi, Saad Bin Anis, Muhammad Shahzad Shamim, Asra Tanwir, Syed Ather Enam
Summary: Compared to non-giant macroadenomas, giant pituitary adenomas are more likely to present with a higher number of preoperative symptoms and have lesser chances of complete resection. They are also associated with a higher rate of recurrence, leading to more follow-up procedures. Larger, multi-center longitudinal studies are needed to validate these findings.
JOURNAL OF NEURO-ONCOLOGY
(2022)
Article
Medicine, General & Internal
Taieb Ach, Wissal Ben Yahia, Imen Halloul, Fatma Sghaier, Amira Atig
Summary: This is a report about a rare case of a female patient who was misdiagnosed as a pituitary adenoma and was finally diagnosed with inflammatory pituitary lesion through neurosurgical transsphenoidal surgery. Histological examination revealed granulomatous hypophysitis, while specific testing for Mycobacterium tuberculosis was negative. After excluding other possible causes, the final diagnosis was neurosarcoidosis. Understanding the different MRI aspects of neurosarcoidosis is essential to avoid misdiagnosis.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Sebastien Dejust, Benedicte Decoudier, Brigitte Higel, Claude-Fabien Litre, David Morland
Summary: This case report describes a 69-year-old male with stage IV pulmonary adenocarcinoma, who presented with decreased visual acuity. Imaging studies revealed a pituitary macroadenoma with a large cyst compressing the optic chiasma, leading to panhypopituitarism. Pathology confirmed the presence of pituitary apoplexy in a gonadotropin-secreting macroadenoma, with no malignant cells detected. Molecular imaging may play a key role in detecting and characterizing pituitary tumors.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Clinical Neurology
Yu Zhang, Yuqi Luo, Xin Kong, Tao Wan, Yunling Long, Jun Ma
Summary: The MRI-based radiomics-clinicopathological model showed superior predictive performance in predicting pituitary macroadenoma recurrence within 5 years, compared to the clinical model. Model 2, which combined radiomics features with independent clinicopathological risk factors, demonstrated higher accuracy, sensitivity, and specificity than Model 1.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Kihwan Hwang, Yong Hwy Kim, Jung Hee Kim, Jung Hyun Lee, Hee Kyung Yang, Jeong-Min Hwang, Chae-Yong Kim, Jung Ho Han
Summary: The study on the natural history of asymptomatic nonfunctioning pituitary adenomas (NFPAs) with optic nerve compression showed that close follow-up and timely surgical intervention can effectively prevent visual and endocrine issues for cases with optic nerve compression, and conservative management is also acceptable for these tumors. Careful follow-up is necessary for tumors with cavernous sinus invasion.
JOURNAL OF NEUROSURGERY
(2021)
Review
Oncology
Huiying Yan, Chaolong Yan, Jiannan Mao, Wei Jin
Summary: This article reports a rare case of TSHoma with diffuse calcification presenting with hyperthyroidism. The tumor was completely removed via endoscopic transnasal-transsphenoidal surgery, and the thyroid function was normalized after the operation.
FRONTIERS IN ONCOLOGY
(2023)
Article
Endocrinology & Metabolism
Oriol Mirallas, Francesca Filippi-Arriaga, Irene Hernandez Hernandez, Anton Aubanell, Anas Chaachou, Alejandro Garcia-Alvarez, Jorge Hernando, Elena Martinez-Saez, Betina Biagetti, Jaume Capdevila
Summary: Nelson's syndrome is a severe side effect that can occur after total bilateral adrenalectomy in patients with Cushing's disease, presenting with symptoms of pituitary tumor enlargement. Chemotherapy with capecitabine and temozolomide is sometimes considered as an off-label treatment option, but its effectiveness is controversial due to adverse events and unpredictable results.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Clinical Neurology
Ankur Gupta, Mira Deshmukh, George Palexas
Summary: This is a rare presentation of a pituitary macroadenoma in a 35-year-old primigravida woman, with chiasmal compression discovered after delivery. The tumor was largely symmetrical, making it even more unusual.
JOURNAL OF NEURO-OPHTHALMOLOGY
(2021)
Article
Oncology
Moran Amit, Ahmed S. Abdelmeguid, Teemaranawich Watcherporn, Hideaki Takahashi, Samantha Tam, Diana Bell, Renata Ferrarotto, Bonnie Glisson, Michael E. Kupferman, Dianna B. Roberts, Shirley Y. Sue, Shaan M. Raza, Franco DeMonte, Ehab Y. Hanna
JOURNAL OF CLINICAL ONCOLOGY
(2019)
Article
Medicine, Research & Experimental
Samantha Tam, Chi-Fang Wu, Ho-Lan Peng, Kristina R. Dahlstrom, Erich M. Sturgis, David R. Lairson
Article
Oncology
Samantha Tam, Randal S. Weber, Jun Liu, Jose Ting, Summer Hanson, Carol M. Lewis
ANNALS OF SURGICAL ONCOLOGY
(2020)
Editorial Material
Oncology
Samantha Tam, Randal S. Weber, Carol M. Lewis
ANNALS OF SURGICAL ONCOLOGY
(2020)
Article
Multidisciplinary Sciences
Moran Amit, Hideaki Takahashi, Mihnea Paul Dragomir, Antje Lindemann, Frederico O. Gleber-Netto, Curtis R. Pickering, Simone Anfossi, Abdullah A. Osman, Yu Ca, Rong Wang, Erik Knutsen, Masayoshi Shimizu, Cristina Ivan, Xiayu Rao, Jing Wang, Deborah A. Silverman, Samantha Tam, Mei Zhao, Carlos Caulin, Assaf Zinger, Ennio Tasciotti, Patrick M. Dougherty, Adel El-Naggar, George A. Calin, Jeffrey N. Myers
Article
Otorhinolaryngology
Samantha Tam, Christopher M. K. Yao, Moran Amit, Mona Gajera, Xiaoning Luo, Rachel Treistman, Anshu Khanna, Mohamed Aashiq, Priyadharsini Nagarajan, Diana Bell, Adel El-Naggar, Michael Migden, Michael Wong, Bonnie Glisson, Renata Ferrarotto, Bita Esmaeli, David Rosenthal, Guojun Li, Randal S. Weber, Jeffrey N. Myers, Neil D. Gross
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2020)
Letter
Oncology
Moran Amit, Samantha Tam, Tarif Bader, Alex Sorkin, Avi Benov
EUROPEAN JOURNAL OF CANCER
(2020)
Article
Medicine, Research & Experimental
Karen Y. Choi, Moran Amit, Samantha Tam, Diana Bell, Jack Phan, Adam S. Garden, Michelle D. Williams, Renata Ferrarotto, Adel K. El-Naggar, Shaan M. Raza, Franco DeMonte, Michael E. Kupferman, Ehab Y. Hanna, Shirley Y. Su
Summary: The study evaluated the incidence of histopathologic diagnostic discrepancies in sinonasal cancer patients, finding a 24% discordance rate in major diagnoses. Patients with major diagnostic changes had lower overall survival and disease-specific survival, especially those who had undergone previous treatment.
Review
Oncology
Melissa G. Lechner, Angeli C. Bernardo, Alyssa Lampe, Stephanie Smooke Praw, Samantha H. Tam, Trevor E. Angell
Summary: The study compared the differences between AJCC-7 and AJCC-8 in staging methods for differentiated thyroid cancer. It found that AJCC-8 reclassified patients into earlier clinical stages and better stratified disease-specific mortality risk.
Article
Oncology
Moran Amit, Chuan Liu, Frederico O. Gleber-Netto, Sameer Kini, Samantha Tam, Avi Benov, Mohamed Aashiq, Adel K. El-Naggar, Amy C. Moreno, David I. Rosenthal, Bonnie S. Glisson, Renata Ferrarotto, Michael K. Wong, Michael R. Migden, Erez N. Baruch, Guojun Li, Anshu Khanna, Ryan P. Goepfert, Priyadharsini Nagarajan, Randal S. Weber, Jeffrey N. Myers, Neil D. Gross
Summary: The study included 1258 patients with cutaneous head and neck squamous cell carcinoma and showed that the number of metastatic lymph nodes and the presence of extranodal extension are independent prognostic factors for disease-specific survival. Incorporating these factors into staging systems can improve the performance of the American Joint Committee on Cancer lymph node classification.
Article
Oncology
Samantha Tam, Wenli Dong, David M. Adelman, Randal S. Weber, Carol M. Lewis
Article
Otorhinolaryngology
Ilaaf Darrat, Samantha Tam, Marwan Boulis, Amy M. Williams
Summary: The study findings suggest that demographic factors such as age, sex, median household income, insurance status, and marital status are associated with patient participation in telehealth during the COVID-19 pandemic.
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2021)
Article
Oncology
Moran Amit, Chuan Liu, Frederico-Omar Netto Gleber, Sameer Kini, Samantha Tam, Avi Benov, Mohamed Aashiq, Adel K. El-Naggar, Amy C. Moreno, David Rosenthal, Bonnie S. Glisson, Renata Ferrarotto, Michael K. Wong, Michael R. Migden, Guojun Li, Anshu Khanna, Ryan P. Goepfert, Priyadharsini Nagarajan, Randal S. Weber, Jeffrey N. Myers, Neil D. Gross
Summary: The study assessed the prognostic performance of six modified T-classification models in head and neck CSCC patients, with model 6 showing superiority over the AJCC staging system. Incorporating depth of invasion into the current staging system improves discrimination of T classifications in head and neck CSCC patients.
EUROPEAN JOURNAL OF CANCER
(2021)
Letter
Otorhinolaryngology
Samantha Tam, Vivian F. Wu, Amy M. Williams, Marian Girgis, Jawad Z. Sheqwara, Farzan Siddiqui, Steven S. Chang
Summary: This cohort study investigates the relationship between patient demographic characteristics and socioeconomic status with engagement in telemedicine during the COVID-19 pandemic.
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2021)
Article
Medicine, Research & Experimental
Aditi Kappagantu, Kathleen Yaremchuk, Samantha Tam
Summary: This study analyzed electric scooter injuries in US emergency departments from January 2009 to December 2019, finding that head and neck injuries accounted for 28.5% of total injuries. Following the introduction of rideshare electric scooter programs in 2018 to 2019, injuries in the 18- to 44-year-old age group significantly increased.