Article
Microbiology
Karolina Plaskowska, Lukasz Makowski, Agnieszka Strzalka, Jolanta Zakrzewska-Czerwinska
Summary: Most eukaryotic and bacterial cells divide by binary fission, while some bacteria can also divide by nonbinary fission. The predatory bacterium Bdellovibrio bacteriovorus exhibits bimodal fission, with the mode of division depending on the size of the prey bacterium. This finding provides insights into the proliferation and elimination strategies of antibiotic-resistant pathogens.
Article
Materials Science, Multidisciplinary
Christian Mariel Saenz-Santos, Omotayo Opemipo Oyedara, Yunia Veronica Garcia-Tejeda, Claudia A. Romero-Bastida, Esperanza Milagros Garcia-Oropesa, Eduardo Villalobo, Mario A. Rodriguez-Perez
Summary: The study evaluated the viability of Bdellovibrio bacteriovorus in biopolymeric films, with CA-S film showing less reduction in bacterial viability. This suggests that CA-S could be a better agent for immobilization and preservation of B. bacteriovorus for enhanced predatory activities against Escherichia coli.
Editorial Material
Microbiology
R. Elizabeth Sockett
Summary: Liz Sockett describes the lessons she learned from studying Bdellovibrio bacteriovorus, a single-celled predator that invades and kills Gram-negative bacteria from within.
NATURE MICROBIOLOGY
(2023)
Review
Microbiology
Ting F. Lai, Rhian M. Ford, Simona G. Huwiler
Summary: Since its discovery, the predatory bacterium Bdellovibrio bacteriovorus has attracted attention as a potential solution to antibiotic resistance. This review provides a comprehensive historical overview and discusses the advancements in microscopy and molecular mechanisms. Recent findings in cryo-electron tomography have revealed intricate molecular details of the predatory life cycle, and new imaging technologies and quantitative advances are expected to unravel remaining unanswered questions in the future.
FRONTIERS IN MICROBIOLOGY
(2023)
Review
Microbiology
J. Kimberley Summers, Jan-Ulrich Kreft
Summary: With the increasing levels of antimicrobial resistance, there is an urgent need for novel means of treating resistant infections. Bacteriophages and predatory bacteria have been proposed as suitable candidates for this role. Mathematical models have been used to investigate the mechanisms of action of predators and predict the dynamics of predator-prey systems. These models have also provided insights into the qualitative and quantitative similarities or differences between bacterial predators and bacteriophages or protists. Additionally, models have helped study the effectiveness of predators in removing prey species and their potential effects on shaping ecosystems. Overall, mathematical models have played a crucial role in understanding and predicting the behavior of prokaryotic predators.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Yuki Hoshiko, Yoshito Nishiyama, Tae Moriya, Kiwao Kadokami, Luis Esau Lopez-Jacome, Ryutaro Hirano, Rodolfo Garcia-Contreras, Toshinari Maeda
Summary: The study found that the pqs QS system of P. aeruginosa inhibits the predatory activity of B. bacteriovorus, while the predatory activity of B. bacteriovorus increases when using pqs QS system mutant strains.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Yan Liu, Wanting Guo, Wanmei Wang, Hui Zhang, Yiguang Jin
Summary: The development of potent bactericidal antibiotic alternatives is crucial to address the current antibiotic crisis. This study constructed a B. bacteriovorus in situ forming hydrogel (BIG) for the local treatment of drug-resistant bacterial ocular infection. BIG not only preserved the activity of B. bacteriovorus but also remained on the ocular surface for a prolonged period.
JOURNAL OF CONTROLLED RELEASE
(2023)
Article
Materials Science, Multidisciplinary
Ying Tang, Qian-Xiao Huang, Di-Wei Zheng, Yang Chen, Li Ma, Cui Huang, Xian-Zheng Zhang
Summary: By utilizing a material-assisted micro-organism (MAMO) strategy with ZnO nanorods engineered Bdellovibrio (ZnO@Bdello), the biofilm composed of Gram-negative bacteria can be effectively eradicated. This strategy demonstrates superior competence in alleviating inflammation and inhibiting bone resorption.
Review
Pharmacology & Pharmacy
Camila Maurmann de Souza, Osmel Fleitas Martinez, Harry Morales Duque, Octavio Luiz Franco
Summary: Novel treatments are needed to combat resistant Gram-negative bacteria and predatory bacteria have emerged as a potential solution. However, the efficacy of predatory bacteria alone is limited, leading to the investigation of combination therapies with other agents. This article discusses recent advancements in the use of predatory bacteria for infections and proposes novel combination strategies with antivirulence compounds.
DRUG DISCOVERY TODAY
(2023)
Review
Microbiology
Benjamin Havenga, Brandon Reyneke, Monique Waso-Reyneke, Thando Ndlovu, Sehaam Khan, Wesaal Khan
Summary: This article reviews the antibiotic resistance and virulence mechanisms of A. baumannii, and discusses the potential of biological control agents to target and combat this pathogen. Limitations and mitigation strategies are also outlined.
Article
Microbiology
Emma J. Banks, Carey Lambert, Samuel S. Mason, Jess Tyson, Paul M. Radford, Cameron McLaughlin, Andrew L. Lovering, R. Elizabeth Sockett
Summary: Antimicrobial resistance poses a serious threat to global health. Bdellovibrio bacteriovorus has the potential to be a novel antibacterial therapeutic and a source of antibacterial enzymes by preying upon Gram-negative bacterial pathogens. This study reveals the role of a secreted lytic transglycosylase from B. bacteriovorus in targeting the septal peptidoglycan of its prey.
JOURNAL OF BACTERIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Connor D. Harris, Ellis L. Torrance, Kasie Raymann, Louis-Marie Bobay
Summary: The core genome represents the set of genes shared by all, or nearly all, strains of a given population or species of prokaryotes. CoreCruncher is a robust and fast program that can construct core genomes across hundreds or thousands of genomes. Compared to other tools, CoreCruncher is more conservative and less sensitive to the presence of paralogs and xenologs.
MOLECULAR BIOLOGY AND EVOLUTION
(2021)
Review
Microbiology
Francis M. Cavallo, Lorea Jordana, Alexander W. Friedrich, Corinna Glasner, Jan Maarten van Dijl
Summary: Bdellovibrio bacteriovorus is a predatory bacterium with potential applications as a probiotic and antibiotic agent due to its unique ability to prey on other Gram-negative bacteria. Recent studies have focused on its biology, life cycle, predation resistance, and potential use as a living antibiotic in human therapy. Data suggest that it could be upgraded from academic interest to a tool for combating antibiotic resistant infections.
CRITICAL REVIEWS IN MICROBIOLOGY
(2021)
Article
Engineering, Environmental
Megan Kode, Monique Waso-Reyneke, Brandon Reyneke, Julia Denissen, Tanya Clements-Decker, Benjamin Havenga, Sehaam Khan, Wesaal Khan
Summary: This study investigated the reduction of antibiotic resistant Klebsiella pneumoniae and Pseudomonas aeruginosa using combination treatments of Bdellovibrio bacteriovorus, solar disinfection, and Moringa oleifera flocculation. Results showed that pre-treatment with Bdellovibrio bacteriovorus alone did not reduce the concentration of Pseudomonas aeruginosa, but combining it with solar disinfection resulted in significant reductions. The combination treatment effectively reduced the counts of Klebsiella pneumoniae.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Fisheries
Xiaoli Chen, Huadong Yi, Shuang Liu, Yong Zhang, Yuqin Su, Xuange Liu, Sheng Bi, Han Lai, Zeyu Zeng, Guifeng Li
Summary: Addition of B. bacteriovorus to aquaculture water can significantly promote the pellet-feed feeding of mandarin fish, improve their survival rates and growth performance, as well as regulate intestinal flora and enhance innate immunity.
Article
Microbiology
K. M. James, K. W. MacDonald, R. M. Chanyi, P. A. Cadieux, J. P. Burton
JOURNAL OF MEDICAL MICROBIOLOGY
(2016)
Article
Environmental Sciences
Ryan M. Chanyi, Susan F. Koval, Joanna S. Brooke
ENVIRONMENTAL MICROBIOLOGY REPORTS
(2016)
Article
Nutrition & Dietetics
Ruth Harvie, Ryan M. Chanyi, Jeremy P. Burton, Michael Schultz
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS
(2017)
Article
Medicine, General & Internal
Ryan M. Chanyi, Raidh Alzubaidi, Everett J. Y. Leung, Hannah B. Wilcox, Gerald B. Brock, Jeremy P. Burton
Letter
Biochemistry & Molecular Biology
Ryan M. Chanyi
CANADIAN JOURNAL OF MICROBIOLOGY
(2018)
Article
Ecology
Z. Pasternak, M. Njagi, Y. Shani, R. Chanyi, O. Rotem, M. N. Lurie-Weinberger, S. Koval, S. Pietrokovski, U. Gophna, E. Jurkevitch
Article
Multidisciplinary Sciences
Ryan M. Chanyi, Susan F. Koval
Article
Multidisciplinary Sciences
Brendan A. Daisley, Ryan M. Chanyi, Kamilah Abdur-Rashid, Kait F. Al, Shaeley Gibbons, John A. Chmiel, Hannah Wilcox, Gregor Reid, Amanda Anderson, Malcolm Dewar, Shiva M. Nair, Joseph Chin, Jeremy P. Burton
NATURE COMMUNICATIONS
(2020)
Article
Food Science & Technology
Hanh T. H. Nguyen, Mariza Gomes Reis, Yunchao Wa, Renna Alfante, Ryan M. M. Chanyi, Eric Altermann, Li Day
Summary: Texture and flavour, which are crucial attributes for sensory quality, are greatly influenced by starter cultures. Different phenotypic strains are required to create diverse texture and flavour in fermented milk to meet consumer preferences. This study investigated the use of five lactic acid bacteria strains in fermented milk production, looking at metabolite profiles, microstructure, and rheological properties. LH and ST showed stronger acidification but resulted in coarser protein networks compared to BL1 and CL3. LH had the highest viscosity and exopolysaccharide concentration, while ST had the highest concentration of diacetyl. CL3ST had minimal acidification capability but produced high levels of ethyl-derived compounds associated with sweet, fruity, and floral fragrances. LH and ST can be used as starter cultures for fermented milks with different viscosities, while BL1, CL3, and CL3ST are suitable as adjunct cultures for different acidic sharpness and flavour notes.
Article
Oncology
Saman Maleki Vareki, Ryan M. Chanyi, Kamilah Abdur-Rashid, Liam Brennan, Jeremy P. Burton
ECANCERMEDICALSCIENCE
(2018)
Article
Biochemistry & Molecular Biology
Damian McNeely, Ryan M. Chanyi, James S. Dooley, John E. Moore, Susan F. Koval
CANADIAN JOURNAL OF MICROBIOLOGY
(2017)
Review
Oncology
Yige Bao, Kait F. Al, Ryan M. Chanyi, Samantha Whiteside, Malcom Dewar, Hassan Razvi, Gregor Reid, Jeremy P. Burton
ANNALS OF TRANSLATIONAL MEDICINE
(2017)