Journal
JOURNAL OF DERMATOLOGY
Volume 42, Issue 10, Pages 941-944Publisher
WILEY
DOI: 10.1111/1346-8138.13083
Keywords
chemokine; mycosis fungoides; pathogenesis; Sezary syndrome; treatment
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Mycosis fungoides and Sezary syndrome are T-helper (Th)2-skewed cutaneous lymphomas. The clinical course of mycosis fungoides is classically indolent, manifesting as patches, plaques and tumors. Along with their progression, Th2 dominance tends to be accelerated. In this review, we discuss the epidemiology, clinicopathogenetic features and therapeutic approaches in mycosis fungoides and Sezary syndrome.
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