Article
Biochemistry & Molecular Biology
Olga Kiseleva, Ilya Kurbatov, Ekaterina Ilgisonis, Ekaterina Poverennaya
Summary: Metabolomics analyzes metabolites in biological samples, particularly blood and its liquid components: plasma and serum, using advanced analytical chemistry methods. It has been found that small molecules play diverse roles in living systems beyond traditional building blocks or cellular energy fuel, leading to practical applications in molecular medicine and a better understanding of fundamental biochemical processes.
Article
Biochemical Research Methods
Nerea Lorenzo-Parodi, Erich Leitner, Torsten C. Schmidt
Summary: This study compares three gas chromatographic methods for analyzing ten iodinated derivatives of aromatic amines, and finds that all methods and most analytes have good detection limits and precision. Urine samples from smokers and non-smokers were successfully analyzed, and differences in concentration were observed.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Analytical
Maartje Verhoeven, Jennifer Bonetti, Ruben Kranenburg, Arian van Asten
Summary: Due to the increasing number of NPSs, identifying drug isomers is becoming more challenging for forensic laboratories. Currently, GC-MS is the standard technique, but it cannot confidently differentiate positional isomers. This review provides an overview of methods for differentiating and identifying NPS positional isomers and proposes a workflow for routine analysis in forensic laboratories.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Health Care Sciences & Services
Roman Zazula, Michal Moravec, Frantisek Pehal, Tomas Nejtek, Marek Protus, Martin Muller
Summary: Myristic acid has been identified as a metabolite with high diagnostic sensitivity and specificity in patients with bacteraemia, sepsis, and SIRS. Its levels are significantly associated with severe trauma outcomes and inflammatory responses, making it a potential candidate marker for severe inflammation and sepsis. Patients with infection tended to have higher levels of myristic acid, especially within the first 24 hours of diagnosis.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Plant Sciences
Li-Ting Ma, Pi-Ling Liu, Yang-Tui Cheng, Tz-Fan Shiu, Fang-Hua Chu
Summary: This study used transcriptome mining and functional characterization to uncover the activity of several monoterpene synthases in Taiwania cryptomerioides, and compared their evolutionary characteristics. The results suggest that there may be crucial regions in the catalytic residues of Cupressaceae monoterpene synthases, which help determine the formation of different monoterpenes.
Article
Chemistry, Applied
Tetsuya Sasaki, Nobuo Ochiai, Yuya Yamazaki, Kikuo Sasamoto
Summary: This study characterized the aroma compounds in Yamahai-brewed sake using SA-SBSE with GC-O/MS. The analysis showed that Yamahai-brewed sake had higher content of several compounds compared to Sokujo-brewed sake.
Review
Chemistry, Analytical
Carlos A. Valdez
Summary: The misuse of synthetic opioids belonging to the fentanyl class has raised serious safety concerns, prompting efforts worldwide to find effective solutions. Key research areas include controlling production and distribution, developing detection methods, and finding efficient antidotes. The review article summarizes the current literature on the detection and identification of synthetic opioids using GC-MS methods.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Maria Fernanda S. Mota, Habtewold D. Waktola, Yada Nolvachai, Philip J. Marriott
Summary: This article provides an overview of recent advances in the analysis of seed and vegetable oils, highlighting the importance of authenticity of food oils and selected applications of contaminants analysis. It also includes a brief comparison of separation technologies and concludes by emphasizing recent advances and future trends.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Food Science & Technology
Jie Wang, Xiaohan Li, Ying Wu, Fengfeng Qu, Lei Liu, Baoyi Wang, Peiqiang Wang, Xinfu Zhang
Summary: This study analyzed the volatile compounds in green tea produced in different seasons using GC-MS. The results showed that the volatile compound composition differed in spring, summer, and autumn green tea. PCA, PLS-DA, and HCA analysis classified the samples and identified key characteristic compounds. The findings contribute to our understanding of seasonal variations in green tea and provide a basis for quality control in production.
Article
Endocrinology & Metabolism
Qingying Si, Jinxiu Guo, Xiumei Yang, Yujin Guo, Linlin Wu, Dadi Xie, Pei Jiang
Summary: This study investigated the metabolic alterations in streptozotocin-induced diabetic rats using gas chromatography-mass spectrometry analysis. The results showed differential expression of metabolites in the serum, heart, liver, kidney, cortex, renal lipid, hippocampus, and brown fat tissues of diabetic rats compared to control rats. Metabolic pathway analysis revealed that these alterations mainly involved amino acid metabolism, organic acid metabolism, sugar metabolism, and lipid metabolism.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Food Science & Technology
Hong Zeng, Yadong Wang, Haoying Han, Yanping Cao, Bei Wang
Summary: Monascus-fermented cheese (MC) is a new type of mold-ripened cheese that combines traditional Chinese fermentation fungus with Western cheese fermentation techniques. The study found that the esterase activity in MC was higher during the ripening period, and the key odor features of ripened MC were alcohol and fruity flavors.
Article
Acoustics
Linjie Xi, Yanan Sun, Shengqi Jiang, Chunlu Wen, Wu Ding
Summary: Ultrasound-assisted curing has a significant impact on the flavor formation of Chinese bacon. Through the analysis of phospholipid and lipase, the study determined the fundamental precursors of ultrasonic on the flavor of Chinese bacon. The differences in flavor between the ultrasonic treatment group and the control group were mainly due to changes in the W1W sensor. A total of 28 volatile compounds were detected by GC-MS, and the aldehyde content increased with ultrasonic power. PC and PE were identified as the main flavor precursors in the curing process. This study provides a theoretical basis for improving the curing technology of Chinese bacon.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Biochemical Research Methods
Sarah Schlag, Yining Huang, Walter Vetter
Summary: A novel GC/MS-SIM method was developed for comprehensive analysis of sterols, using a new referencing system and retention time locking. This method involved measuring multiple SIM ions, including molecular ions of sterols and abundant ions of FAPs. The screening of common vegetable oils enabled the detection and identification of numerous sterols and triterpenes.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Chula Sa, Jinlei Liu, Yu Dong, Li Jiang, Ge Gentana, Amin Wurita
Summary: The study successfully developed and validated a GC-MS/MS method for quantitative analysis of eucalyptol in rat serum, and applied it to a pharmacokinetic study, showing that the absorption characteristics of orally administered eucalyptol are similar to intravenously administered eucalyptol.
BIOMEDICAL CHROMATOGRAPHY
(2021)
Article
Food Science & Technology
Zhenzhao Li, Minh Ha, Damian Frank, Peter McGilchrist, Robyn Dorothy Warner
Summary: The study found that the concentration of volatiles with high odor impact is higher in dry aged beef, and certain odor impact compounds decrease significantly with ageing time. Consumer preference for 35-day dry aged beef is associated with higher concentrations of pleasant odor-active volatiles.
