Article
Peripheral Vascular Disease
Kazuo Kobayashi, Keiichi Chin, Nobuo Hatori, Takayuki Furuki, Hiroyuki Sakai, Masaaki Miyakawa, Kei Asayama, Narumi Eguchi, Tomohiro Katsuya, Kouichi Tamura, Kazuyoshi Sato, Akira Kanamori
Summary: The study aimed to assess the data of hypertensive patients in Kanagawa Prefecture, Japan, collected in 2021. Comparative analysis was conducted using data collected in 2011 and 2014. The achievement rates of target blood pressure were lower in 2021 compared to 2011 and 2014. Furthermore, after the release of the Japanese Society of Hypertension 2019 Guidelines, the achievement rates for patients with tightened target blood pressure were significantly lower.
HYPERTENSION RESEARCH
(2023)
Article
Medicine, General & Internal
Richu Philip, Thomas Beaney, Nick Appelbaum, Carmen Rodriguez Gonzalvez, Charlotte Koldeweij, Amelia Kataria Golestaneh, Neil Poulter, Jonathan M. Clarke
Summary: The study found that clinical practice guidelines for hypertension were generally consistent in defining, staging, and recommending target blood pressure, but showed extensive variation in treatment recommendations, especially for second-line therapy. Low-income countries tended to recommend cheaper drugs, offered less choice to clinicians in medications, and initiated dual therapy at later stages compared to high-income countries. Future research could explore underlying drivers of this variation to improve outcomes for hypertensive patients across different clinical contexts.
Review
Cardiac & Cardiovascular Systems
Abu Baker Sheikh, Paul A. Sobotka, Ishan Garg, Jessilyn P. Dunn, Abdul Mannan Khan Minhas, Md Mobashir Hasan Shandhi, Jeroen Molinger, Barry J. McDonnell, Marat Fudim
Summary: Recent advancements in wearable technology have made it possible to continuously and noninvasively monitor blood pressure, heart rate, and heart rhythm. These systems can track various aspects of blood pressure variability and changes in underlying heart rhythm, providing valuable diagnostic and therapeutic insights. Blood pressure variability is a strong risk factor for cardiovascular diseases, chronic kidney disease, cognitive decline, and mental illness.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Multidisciplinary Sciences
Teodora Yaneva-Sirakova, Latchezar Traykov
Summary: The combination of mild cognitive impairment (MCI) and cardiovascular risk factors, particularly arterial hypertension, may lead to a higher mortality rate. This hypothesis is important for effective early screening and prevention.
SCIENTIFIC REPORTS
(2022)
Review
Peripheral Vascular Disease
Indranil Dasgupta, Carmine Zoccali
Summary: Meticulous management of hypertension is crucial for reducing the risk of cardiovascular disease, mortality, and progression of CKD in patients with chronic kidney disease. However, the recently published KDIGO guideline's recommendation of a systolic blood pressure target of <120 mm Hg is controversial and not applicable to the majority of CKD patients.
Review
Cardiac & Cardiovascular Systems
Justin Chia, Kunwardeep S. Bhatia, Anastasia S. Mihailidou, Logan B. Kanagaratnam
Summary: Hypertension remains the leading modifiable risk factor for stroke, kidney disease, and cardiovascular disease, and is a significant contributor to preventable deaths worldwide. Utilizing ambulatory blood pressure monitoring (ABPM) can enhance the accurate diagnosis of hypertension and identify specific subtypes such as white coat hypertension and masked hypertension, as well as assess a patient's nocturnal blood pressure status. Familiarity with the use of ABPM is crucial for optimal management of patients with hypertension.
HEART LUNG AND CIRCULATION
(2022)
Review
Medicine, General & Internal
Giuliano Tocci, Barbara Citoni, Giulia Nardoianni, Ilaria Figliuzzi, Massimo Volpe
Summary: Hypertension is a common cardiovascular risk factor, and controlling it is crucial for reducing complications and mortality. International guidelines recommend systematic out-of-office blood pressure measurements to improve awareness and adherence to medication, ultimately leading to better control of hypertension.
INTERNAL AND EMERGENCY MEDICINE
(2022)
Article
Peripheral Vascular Disease
George S. Stergiou, Ioanna Bountzona, Christina Alamara, Andriani Vazeou, Anastasios Kollias, Angeliki Ntineri
Summary: This study demonstrates that in children and adolescents, 24-hour ABP and 7-day HBP have similar reproducibility, superior to OBP and daytime or asleep ABP. This has significant implications for diagnosing hypertension in children in clinical practice and designing clinical research trials in pediatric hypertension.
Article
Peripheral Vascular Disease
Nelson Wang, Katie Harris, Mark Woodward, Stephen Harrap, Giuseppe Mancia, Neil Poulter, John Chalmers, Anthony Rodgers
Summary: The utility of short-term blood pressure changes in determining long-term treatment response was assessed in two randomized trials, and it was found that changes in blood pressure immediately after starting treatment did not significantly affect subsequent treatment response.
Article
Cardiac & Cardiovascular Systems
Yaxing Meng, Costan G. Magnussen, Feitong Wu, Markus Juonala, Marie-Jeanne Buscot, Katja Pahkala, Nina Hutri-Kahonen, Mika Kahonen, Tomi Laitinen, Jorma S. A. Viikari, Olli T. Raitakari, James E. Sharman
Summary: Within-visit blood pressure variability can influence blood pressure classification, highlighting the importance of consistency in measuring blood pressure.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Pediatrics
Ifeoma Atoh, Joseph Ezeogu, Ekanem Ekure, Samuel Ilenre Omokhodion, Fidelis Olisamedua Njokanma
Summary: This study evaluated the impact of the 2017 AAP Clinical Guideline on the prevalence of high blood pressure among adolescents compared to the 2004 Fourth Report. The results showed that the 2017 guideline detected a higher proportion of high blood pressure cases among adolescents, with an increase in prevalence rates of 12.2%, 7.7%, and 4.5% for high blood pressure, elevated blood pressure, and hypertension, respectively.
FRONTIERS IN PEDIATRICS
(2023)
Article
Geriatrics & Gerontology
Alexandra Papaioannou, George Ioannidis, Caitlin McArthur, Loretta M. Hillier, Sid Feldman, Lora Giangregorio, Susan Jaglal, Ravi Jain, Mary-Lou Van der Horst, Jonathan Adachi
Summary: This research successfully lowered fracture rates in LTC in Ontario through multifaceted knowledge translation strategies, identifying challenges and solutions in fracture prevention.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Peripheral Vascular Disease
Chia-Te Liao, Han Siong Toh, Chun-Ting Yang, Chien-Yi Hsu, Mei-Chuan Lee, Wei-Ting Chang, Zhih-Cherng Chen, Hung-Yu Chang, Carol Strong
Summary: Taiwan's new blood-pressure treatment target shows cost-effectiveness in preventing cardiovascular events, consistent across different ages and cardiovascular risks.
HYPERTENSION RESEARCH
(2023)
Article
Peripheral Vascular Disease
Keisuke Narita, Satoshi Hoshide, Kazuomi Kario
Summary: This study analyzed the association between home and ambulatory blood pressure monitoring and cardiovascular risk in hypertensive outpatients, and found that both home blood pressure and ambulatory blood pressure were independently associated with cardiovascular risk. Home blood pressure had a modest superiority to predict cardiovascular prognosis compared to ambulatory blood pressure.
Editorial Material
Peripheral Vascular Disease
Kazuomi Kario, Masaki Mogi, Satoshi Hoshide
Summary: Despite the challenges of the coronavirus pandemic, hypertension research and initiatives in Asia have been active in the past two years. New guidelines and research data contribute to local practices, and efforts to reduce high salt intake are being made. Drug-resistant hypertension and nocturnal hypertension are important research areas in Asia. Digital therapeutics and other digital strategies show promise in reducing the burden of hypertension. Ongoing research activities and initiatives provide optimism for the management of hypertension in Asia.
HYPERTENSION RESEARCH
(2022)
Review
Cardiac & Cardiovascular Systems
Finlay A. McAlister, Harsh Parikh, Douglas S. Lee, Harindra C. Wijeysundera
Summary: There has been a significant increase in morbidity and mortality during the COVID-19 pandemic, including non-COVID-19 deaths related to cardiovascular diseases. The pandemic has had profound indirect effects, leading to a higher burden of cardiovascular disease and risk factors in both COVID-19 survivors and those who were never infected. This report examines the direct impact of SARS-CoV-2 infection on cardiovascular and cardiometabolic disease burden in survivors, as well as the indirect effects of the pandemic on the cardiovascular health of non-infected individuals. It also discusses the consequences of delayed or foregone healthcare during the pandemic and the broader implications for cardiovascular health and healthcare systems.
CANADIAN JOURNAL OF CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Eloisa Colin-Ramirez, Nariman Sepehrvand, Sarah Rathwell, Heather Ross, Jorge Escobedo, Peter Macdonald, Richard Troughton, Clara Saldarriaga, Fernando Lanas, Robert Doughty, Finlay A. McAlister, Justin A. Ezekowitz
Summary: This study analyzed data from randomized controlled trials to evaluate the effects of sodium restriction on clinical outcomes in heart failure patients. The results showed that sodium restriction did not reduce the risk of death or hospitalization, but it may improve symptoms and quality of life.
CIRCULATION-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Finlay A. A. McAlister, Zoe Hsu, Yuan Dong, Ross T. T. Tsuyuki, Carl van Walraven, Jeffrey A. A. Bakal
Summary: This study compares the outcomes of virtual outpatient visits and in-person visits during the COVID-19 pandemic. The study found that there was a significant increase in the number of virtual visits, but the frequency of visits and prescribing patterns remained stable. Virtual visits were associated with lower risks of emergency visits or hospitalizations for patients with heart failure, hypertension, and diabetes compared to in-person visits.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Health Care Sciences & Services
Weijie Sun, Sunil Vasu Kalmady, Nariman Sepehrvand, Amir Salimi, Yousef Nademi, Kevin Bainey, Justin A. Ezekowitz, Russell Greiner, Abram Hindle, Finlay A. McAlister, Roopinder K. Sandhu, Padma Kaul
Summary: This study explored the feasibility and value of using electrocardiogram (ECG) data to predict mortality risk among emergency and hospitalized patients. By developing and validating machine learning models based on ECG traces, the study showed that deep learning models outperformed models based on ECG measurements in predicting short-term and long-term mortality. The findings highlight the potential of ECG-based models for prognostication at point of care.
NPJ DIGITAL MEDICINE
(2023)
Letter
Cardiac & Cardiovascular Systems
Finlay A. McAlister, Yuan Dong
CANADIAN JOURNAL OF CARDIOLOGY
(2023)
Letter
Medicine, General & Internal
Finlay A. McAlister
CANADIAN MEDICAL ASSOCIATION JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Nariman Sepehrvand, Majid Nabipoor, Erik Youngson, Finlay A. Mcalister, Justin A. Ezekowitz
Summary: This study aimed to explore the time to initiation of triple therapy and identify barriers to its use in patients with de novo heart failure with reduced ejection fraction (HFrEF). The results showed that the time to initiation of triple therapy was slow and its utilization rate was low in patients with HFrEF. Patients who received triple therapy had better clinical outcomes compared to those who did not receive it.
JOURNAL OF CARDIAC FAILURE
(2023)
Article
Multidisciplinary Sciences
Finlay McAlister, Jeffrey Hau, Clare Atzema, Andrew McRae, Laurie Morrison, Lars Grant, Ivy Cheng, Rhonda Rosychuk, Corinne M. Hohl
Summary: This study investigated hospitalized SARS-CoV-2 infected patients in 47 Canadian emergency departments and found that 26% of unrelated hospitalizations were incidental findings of SARS-CoV-2 infection. However, even incidental SARS-CoV-2 infections still caused substantial morbidity/mortality and placed a burden on healthcare resources.
SCIENTIFIC REPORTS
(2023)
Review
Medical Informatics
Christopher Meaney, Therese A. Stukel, Peter C. Austin, Rahim Moineddin, Michelle Greiver, Michael Escobar
Summary: This study reviews several methods for assessing the quality of unsupervised topic models and discusses their advantages and disadvantages. By using different metrics and human judgement, it is found that different quality indices have different impacts on model selection.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Finlay A. Mcalister
EUROPEAN HEART JOURNAL
(2023)
Article
Multidisciplinary Sciences
Corinne M. Hohl, Amber Cragg, Elizabeth Purssel, Finlay A. McAlister, Daniel K. Ting, Frank Scheuermeyer, Maja Stachura, Lars Grant, John Taylor, Josephine Kanu, Jeffrey P. Hau, Ivy Cheng, Clare L. Atzema, Rajan Bola, Laurie J. Morrison, Megan Landes, Jeffrey J. Perry, Rhonda J. Rosychuk
Summary: Half of SARS-CoV-2 hospitalizations during the Omicron wave were for COVID-19. The CDC algorithm was more specific and sensitive than the Massachusetts classification, but underestimated the burden of COVID-19 admissions.
Article
Health Care Sciences & Services
P. Alison Paprica, Monique Crichlow, Donna Curtis Maillet, Sarah Kesselring, Conrad Pow, Thomas P. Scarnecchia, Michael J. Schull, Rosario G. Cartagena, Annabelle Cumyn, Salman Dostmohammad, Keith O. Elliston, Michelle Greiver, Amy Hawn Nelson, Sean L. Hill, Wanrudee Isaranuwatchai, Evgueni Loukipoudis, James Ted McDonald, John R. McLaughlin, Alan Rabinowitz, Fahad Razak, Stefaan G. Verhulst, Amol A. Verma, J. Charles Victor, Andrew Young, Joanna Yu, Kimberlyn McGrail
Summary: This article introduces a project conducted by an international team to test and refine the minimum specification essential requirements (min specs). Through analysis and discussion, an updated set of 15 min specs covering various categories has been integrated into a Canadian national standard. These specifications help organizations and initiatives communicate and compare their responsible and trustworthy data governance and management practices.
INTERNATIONAL JOURNAL OF POPULATION DATA SCIENCE (IJPDS)
(2023)
Article
Primary Health Care
Tu N. Nguyen, Sumeet Kalia, Peter Hanlon, Bhautesh D. Jani, Barbara I. Nicholl, Chelsea D. Christie, Babak Aliarzadeh, Rahim Moineddin, Christopher Harrison, Clara Chow, Martin Fortin, Frances S. Mair, Michelle Greiver
Summary: This study investigated the association between multimorbidity and blood pressure control in people with hypertension attending primary care in Canada. The study found that multimorbidity was associated with better blood pressure control, with conditions such as diabetes, heart failure, ischemic heart disease, schizophrenia, depression/anxiety, dementia, and osteoarthritis being associated with a lower likelihood of uncontrolled blood pressure.
JOURNAL OF PRIMARY CARE AND COMMUNITY HEALTH
(2023)
Article
Health Care Sciences & Services
Jennifer Shuldiner, Tara Kiran, Payal Agarwal, Maryam Daneshvarfard, Kirsten Eldridge, Susie Kim, Michelle Greiver, Iffat Jokhio, Noah Ivers
Summary: This study utilized A&F theory and user-centered design to develop a web-based primary care A&F dashboard. By incorporating user interview data and the team's experience, we designed a dashboard that meets the needs and goals of physicians, including addressing data skepticism, spurring action, and supporting physician engagement in quality improvement work.
JMIR HUMAN FACTORS
(2023)
Article
Primary Health Care
Hamidreza Goodarzynejad, Christopher Meaney, Paula Brauer, Michelle Greiver, Rahim Moineddin, Alan A. Monavvari
Summary: The study reveals a modest increase in average BMI among Canadian adults between 2011 and 2016. Male patients have higher BMI on average compared to female patients, and young adults show the fastest increase in BMI compared to older adults. These findings suggest that current obesity management in primary care fails to moderate weight gain in different age and sex groups, emphasizing the need for preventive measures targeting younger individuals.
CANADIAN FAMILY PHYSICIAN
(2022)
