Article
Agriculture, Dairy & Animal Science
P. Khanal, K. L. Parker Gaddis, M. J. Vandehaar, K. A. Weigel, H. M. White, F. Penagaricano, J. E. Koltes, J. E. P. Santos, R. L. Baldwin, J. F. Burchard, J. W. Durr, R. J. Tempelman
Summary: Residual feed intake (RFI) and feed saved (FS) are important feed efficiency traits that have been increasingly considered in genetic improvement programs. Recent developments in multiple-trait random regression (MTRR) modeling have allowed for more accurate inferences on RFI and FS, particularly considering the effect of change in metabolic body weight (MBW). Although computational challenges are present, the MTRR model offers an efficient strategy for incorporating a wide variety of data recording scenarios in genetic evaluations for feed efficiency.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Kerry Houlahan, Flavio S. Schenkel, Dagnachew Hailemariam, Jan Lassen, Morten Kargo, John B. Cole, Erin E. Connor, Silvia Wegmann, Oliveira Junior, Filippo Miglior, Allison Fleming, Tatiane C. S. Chud, Christine F. Baes
Summary: This study demonstrates that direct selection on residual feed intake can improve feed efficiency in dairy cattle, leading to higher economic response and more favorable selection responses for production and feed efficiency. As selection pressure on residual feed intake increases over time, the selection responses for production, health, and fertility traits may become less favorable.
Article
Agriculture, Dairy & Animal Science
Jing Liu, Sydney N. Stewart, Kelsy Robinson, Qing Yang, Wentao Lyu, Melanie A. Whitmore, Guolong Zhang
Summary: The study revealed that intestinal microbiota has an impact on feed efficiency in chickens, with certain bacterial features showing significant correlation with RFI regardless of the overall diversity of microbiota.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2021)
Article
Genetics & Heredity
Lei Zhao, Yanling Ding, Chaoyun Yang, Pengfei Wang, Zhiyan Zhao, Ying Ma, Yuangang Shi, Xiaolong Kang
Summary: This study identified key genes and functional pathways associated with phenotypic variation in cattle RFI using RNA sequencing. It revealed the potential regulatory role of circRNAs in feed efficiency and the feeding behavior regulation of livestock.
Article
Agriculture, Dairy & Animal Science
Lucile Montagne, Helene Gilbert, Nelly Muller, Nathalie Le Floc'h
Summary: The physiological responses to weaning differed between pig lines selected for different levels of feed efficiency. Pigs from the more efficient line were more sensitive to the weaning stress initially, but ultimately adapted and showed similar performance as pigs from the less efficient line.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2022)
Article
Fisheries
Wenchao Yu, Junyu Liu, Feng Yu, Yawei Shen, Shihai Gong, Yisha Lu, Wenzhu Peng, Yi Wang, Yang Gan, Qizhen Xiao, Xuan Luo, Weiwei You, Caihuan Ke
Summary: This study measured the growth and feed efficiency traits of Pacific abalone and established an individual-based accurate measurement method. The results showed that residual feed intake (RFI) can be used as a suitable trait for indicating the feed efficiency of abalone, and it is genetically correlated with other traits.
Article
Agriculture, Dairy & Animal Science
Hadi Esfandyari, Just Jensen
Summary: The study aimed to develop a procedure for simultaneous analysis of basic records and derive linear traits related to feed efficiency without approximation. A bivariate longitudinal random regression model was used to analyze individual longitudinal records of weight and feed intake from a large group of beef bulls, estimating genetic and permanent environmental covariance functions.
JOURNAL OF ANIMAL SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Rasmus B. Stephansen, Jan Lassen, Jehan F. Ettema, Lars P. Sorensen, Morten Kargo
Summary: In the Nordic countries, breeding values for residual feed intake are crucial for economic progress in animal husbandry. Simulations using the SimHerd model show that economic value is directly related to feed efficiency and plays a key role in determining profit per annual cow.
Article
Agriculture, Dairy & Animal Science
Yawei Zhang, Fuyong Li, Yanhong Chen, Le-Luo Guan
Summary: This study assessed the effects of breed and feed efficiency on rumen microbiota in beef steers. The results showed that breed has an effect on microbial groups, with previous studies focusing mainly on bacteria and archaea. This study is the first to reveal the effect of breed (host genetics) on rumen eukaryotes, highlighting the potential of manipulating and obtaining desirable rumen microbiota using breeding and genetic selection.
Article
Agriculture, Dairy & Animal Science
Juliana Mergh Leao, Sandra Gesteira Coelho, Camila Flavia de Assis Lage, Rafael Alves de Azevedo, Juliana Aparecida Mello Lima, Juliana Campos Carneiro, Alexandre Lima Ferreira, Fernanda Samarini Machado, Luiz Gustavo Ribeiro Pereira, Thierry Ribeiro Tomich, Hilton do Carmo Diniz Neto, Mariana Magalhaes Campos
Summary: Improvements in dairy cattle feed efficiency can reduce feeding costs and environmental impacts. However, correlations between blood, rumen, or morphometric markers and feed efficiency are low, indicating they may not be useful for early identification of more efficient animals.
Article
Agriculture, Dairy & Animal Science
Margreet Heida, Ghyslaine C. B. Schopen, Marinus F. W. te Pas, Birgit Gredler-Grandl, Roel F. Veerkamp
Summary: This study defined alternative traits related to feed intake using existing data and analyzed the phenotypic and genetic relationships among these traits. The results showed that the defined traits had genetic similarities, with selecting one trait potentially leading to an increase in other traits.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
K. T. Williams, K. A. Weigel, W. K. Coblentz, N. M. Esser, H. Schlesser, P. C. Hoffman, R. Ogden, H. Su, M. S. Akins
Summary: The objective of this study was to compare the growth, feed intake, and feed efficiency of postbred dairy heifers with different genomic RFI when offered diets with different energy densities. Results showed that heifers with low RFI had higher daily gains and feed efficiencies when fed a low energy diet.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Carlos Arce-Recinos, Nadia Florencia Ojeda-Robertos, Ricardo Alfonso Garcia-Herrera, Jesus Alberto Ramos-Juarez, Angel Trinidad Pineiro-Vazquez, Jorge Rodolfo Canul-Solis, Luis Enrique Castillo-Sanchez, Fernando Casanova-Lugo, Einar Vargas-Bello-Perez, Alfonso Juventino Chay-Canul
Summary: This study investigated residual feed intake, volatile fatty acid production, and enteric methane emissions in growing Pelibuey sheep. The results showed that low residual feed intake lambs had lower intake of dry matter, organic matter, crude protein, and neutral detergent fiber, resulting in lower methane emissions.
Article
Agriculture, Dairy & Animal Science
M. H. Lidauer, E. Negussie, E. A. Mantysaari, P. Mantysaari, S. Kajava, T. Kokkonen, A. Chegini, T. Mehtio
Summary: In this study, a new metric called regression on expected feed intake (ReFI) was introduced to evaluate the efficiency of feed utilization in dairy cows. Compared to other metrics such as residual feed intake (RFI) and genetic residual feed intake (gRFI), ReFI showed higher genetic variation and heritability in measuring feed efficiency. Selection based on ReFI breeding values resulted in higher milk production and a greater increase in efficiency compared to selection based on RFI or gRFI values.
Article
Genetics & Heredity
Ye Wang, Chenguang Diao, Huimin Kang, Wenjie Hao, Raphael Mrode, Junhai Chen, Jianfeng Liu, Lei Zhou
Summary: Residual feed intake (RFI) is an important indicator for evaluating feed efficiency in pigs. This study compared the prediction performances of a random regression model (RRM) and a traditional animal model for RFI genetic prediction, and found that the RRM with both pedigree and genetic information achieved greater accuracy than the animal model.
FRONTIERS IN GENETICS
(2022)
Article
Otorhinolaryngology
Jovanna Thielker, Mussab Kouka, Orlando Guntinas-Lichius
Summary: The handling of the facial nerve during surgery for parotid cancer is crucial for the patient's long-term quality of life. Standardized dissection and reconstruction techniques are beneficial in preserving the facial nerve, restoring facial function, and improving surgical outcomes.
Review
Otorhinolaryngology
Carlos M. Chiesa-Estomba, Jose A. Gonzalez-Garcia, Eric M. Genden, Cesare Piazza, Orlando Guntinas-Lichius, Vincent Vander-Poorten, Luiz P. Kowalski, Fernando Lopez, Miquel Quer, Juan P. Rodrigo, Alvaro Sanabria, Veronica Fernandez-Alvarez, Carlos Suarez, Oded Cohen, Remco de Bree, Ashok R. Shaha, Antti A. Makitie, Alfio Ferlito
Summary: This study systematically reviewed and qualitatively analyzed methods for vascular perfusion assessment in Head and Neck microsurgical reconstruction. The results indicated that Cook-Swartz IDP is a safe and effective device. Further detailed prospective registration is needed to accurately evaluate results and complications.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Otorhinolaryngology
Mussab Kouka, Josefin Landgraf, Jens Buentzel, Holger Kaftan, Daniel Boeger, Andreas Mueller, Stefan Schultze-Mosgau, Thomas Ernst, Orlando Guntinas-Lichius
Summary: This population-based study investigates the impact of HPV association on overall survival of oral cavity and oropharyngeal squamous cell carcinoma, as well as the incidence of HPV-positive and HPV-negative tumors. The study found that HPV-positive patients had significantly better 5-year survival rates compared to HPV-negative patients. HPV-positive non-smokers were a minority in the study population.
LARYNGO-RHINO-OTOLOGIE
(2023)
Article
Otorhinolaryngology
Josephine Horn, Ralf Tostmann, Christian Dobel, Jan Loehler, Orlando Guntinas-Lichius
Summary: This study investigated the patient orientation and participation in research projects among ENT patients. The results showed that shared decision-making was favored and sufficient communication with doctors was considered important. Most patients felt well informed about treatment steps but had low willingness to participate in research projects. The researchers suggested that more consideration should be given to patients with lower education levels to provide opportunities for their participation in research.
LARYNGO-RHINO-OTOLOGIE
(2023)
Article
Otorhinolaryngology
Hilmar Gudziol, Thomas Bitter, Timo Kirschstein, Kerstin Laute, Ulrike Schade, Orlando Guntinas-Lichius
Summary: This study investigated the olfactory and gustatory disorders in long-COVID patients and found that 90% of patients had pathological chemosensory diagnoses, with pathological olfactory diagnoses being more common than gustatory diagnoses. In a subset of patients, no pathological diagnosis could be confirmed. The study emphasizes the importance of using validated tests to quantify chemical senses.
LARYNGO-RHINO-OTOLOGIE
(2023)
Article
Medicine, General & Internal
Jakob Hochreiter, Eric Hoche, Luisa Janik, Gerd Fabian Volk, Lutz Leistritz, Christoph Anders, Orlando Guntinas-Lichius
Summary: Surface electromyography (EMG) enables the detection of muscle activity in the ear muscles during facial movements in patients with postparalytic facial synkinesis (PFS). This study developed a machine-learning algorithm to detect eyelid closure and smiling in PFS patients using auricular muscle EMG recordings. The algorithm accurately distinguished eye closure and smiling from other facial expressions, demonstrating the potential for using EMG to improve eye closure and smiling in PFS patients through electrostimulation.
Editorial Material
Medicine, General & Internal
Orlando Guntinas-Lichius
Article
Otorhinolaryngology
Jannik Johannsen, Sami Shabli, Jens Peter Klussmann, Orlando Guntinas-Lichius, Jan-Christoffer Lueers
Summary: The ORL-App is a smartphone app that provides further education and training for ORL doctors and those interested in ORL, complementing existing offerings in medical education and training. The app's main feature is a large ORL quiz module in which users can compete against each other. The performance of app users in the quiz module was analyzed, taking into account the questions' categories and the users' level of education.
LARYNGO-RHINO-OTOLOGIE
(2023)
Article
Otorhinolaryngology
Carsten M. Klingner, Orlando Guntinas-Lichius
Summary: Human facial expressions are unique in expressing and communicating emotions, and they share similarities with other cultures and mammals, suggesting a common genetic origin. However, cultural influences and differences also play a role. The complex cerebral network involved in recognizing and expressing emotions through facial expressions can be disrupted by neurological and psychiatric disorders.
LARYNGO-RHINO-OTOLOGIE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Paolo Bossi, Cristina Gurizzan, Orlando Guntinas-Lichius, Razvan Hainarosie, Davide Lancini
Summary: This expert opinion narrative review summarized the current indicated applications of benzydamine and proposed new areas for exploration.
FRONTIERS IN ORAL HEALTH
(2023)
Article
Otorhinolaryngology
Hilmar Gudziol, Thomas Bitter, Ulrike Schade, Kerstin Laute, Orlando Guntinas-Lichius
Summary: This prospective study from a university ENT post-COVID consultation (PCS) found that olfactory and gustatory disorders are among the most common post-COVID-19 complaints, affecting 87% and 42% of patients respectively. These disorders persisted for an average of 11 months and were a burden for both patients and the healthcare system, especially for those with combined olfactory and gustatory damage.
LARYNGO-RHINO-OTOLOGIE
(2023)
Article
Multidisciplinary Sciences
Hyeonsoo Bae, Marko Rodewald, Tobias Meyer-Zedler, Thomas W. Bocklitz, Gregor Matz, Bernhard Messerschmidt, Adrian T. Press, Michael Bauer, Orlando Guntinas-Lichius, Andreas Stallmach, Michael Schmitt, Juergen Popp
Summary: This article reports on the development and application of a compact multi-core fiber optical probe for multimodal non-linear imaging. The probe shows promising compatibility with clinical requirements and produces high-quality images with good morpho-chemical conformity on tissue level. The study also presents a simple and effective reconstruction procedure for satisfactory results. A clear pathway for further development and clinical evaluation is outlined.
SCIENTIFIC REPORTS
(2023)
Article
Pathology
Stephan Ihrler, Abbas Agaimy, Orlando Guntinas-Lichius, Christian Haas, Lukas Greber
Summary: Clinicians and pathologists often find it more difficult to accurately diagnose minor salivary gland tumors compared to major gland tumors. We identified several reasons for this diagnostic difficulty, including frequent incisional biopsies, low-grade cytology in malignant tumors, and poor clinical-pathological communication. The unique anatomical location of minor glands, such as the hard palate, also contributes to diagnostic challenges. Understanding these pitfalls can help improve diagnostic accuracy and reduce misdiagnosis rates.
Article
Neuroimaging
Vasiliki Salvari, Daniela Korth, Evangelos Paraskevopoulos, Andreas Wollbrink, Daniela Ivansic, Orlando Guntinas-Lichius, Carsten Klingner, Christo Pantev, Christian Dobel
Summary: The pathophysiology of tinnitus is associated with changes in both auditory and non-auditory areas of the brain. Using magnetoencephalography, this study found that tinnitus patients had specific activation in fronto-parietal regions when processing a tinnitus tone, indicating a frequency-specific pattern. This suggests that tinnitus is related to specific frequencies of auditory stimuli.
NEUROIMAGE-CLINICAL
(2023)
Article
Oncology
Jonas Ballmaier, Thomas Bitter, Thomas Kuhnt, Orlando Guntinas-Lichius
Summary: Except for glottic laryngeal carcinomas, head and neck tumors are typically diagnosed at advanced stages III/IV rather than early stages I/II. They are mostly squamous cell carcinomas of the oral cavity, pharynx, and larynx, or cervical cancer of unknown primary (CUP) syndrome. Surgery and radiotherapy are equally effective treatments for early stages, with transoral procedures having lower morbidity compared to open procedures. Treatment recommendations vary depending on the location and stage of the tumor.