Article
Pharmacology & Pharmacy
H-K Vo, V-T Le, V-L Nguyen, X-C Dao, D-H Duong, T-L Trinh, V-T Nguyen, H-L Vo, C-H Nguyen, V-L Tran, A-T Nguyen, V-T Hoang, T-A Truong, T-B Nguyen, B-C Chu, T-M Le, T-T-H Dao, T-H Duong, H-Q Ha, T-P-L Trinh, T-T Truong, V-D Phan, T-N-L Pham, T-H Phuong, Q-C Le
Summary: The objective of this study was to evaluate the value of transcranial Doppler (TCD) ultrasonography in diagnosing cerebral vasospasm in SAH patients in Vietnam. The results showed that TCD had a high accuracy in diagnosing vasospasm, with a high predictive diagnostic value. Hemiplegia was the clinical symptom with the highest diagnostic value.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Biotechnology & Applied Microbiology
Yuanyuan Shen, J. Joep van der Harst, Yanji Wei, Reinoud P. H. Bokkers, J. Marc C. van Dijk, Maarten Uyttenboogaart
Summary: This study aims to validate a numerical model developed for assessing personalized circle of Willis (CoW) hemodynamics under pathological conditions. The results showed that the model had good agreement with transcranial Doppler in assessing the flow velocity in the CoW of patients with acute aneurysmal subarachnoid hemorrhage.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Critical Care Medicine
Clement Isola, Jean-Noel Evain, Gilles Francony, Caroline Baud, Anne Millet, Amelie Desrumaux, Isabelle Wroblewski, Jean-Francois Payen, Guillaume Mortamet
Summary: This study investigates the occurrence of cerebral vasospasm in pediatric patients, especially following nontraumatic SAH. The use of TCD and milrinone may be beneficial in the diagnosis and treatment of cerebral vasospasm.
NEUROCRITICAL CARE
(2022)
Article
Acoustics
Randi Connor-Schuler, Steven Phillips, Emory Kuo, Prem Kandiah, Ofer Sadan
Summary: This study aimed to investigate the feasibility and reliability of bedside transcranial point-of-care ultrasound (POCUS) in measuring velocities and diagnosing vasospasm compared with formal non-imaging transcranial Doppler (TCD). The results showed that bedside ultrasound examination can be used to measure velocities and diagnose vasospasm, and the examination time and correlation varied depending on the operator's experience.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Review
Clinical Neurology
Nebojsa Lasica, Vidak Raicevic, Nikola M. Stojanovic, Djula Djilvesi, Igor Horvat, Bojan Jelaca, Filip Pajicic, Petar Vulekovic
Summary: Metabolomics has become a useful tool in studying metabolite interactions and can be applied in clinical settings for diagnostics. This article provides an overview of analytical techniques in metabolomics and focuses on its application in studying brain metabolism and cerebrovascular diseases, particularly aneurysmal subarachnoid hemorrhage. Both animal models and human studies are considered, and potential biomarkers are highlighted.
FRONTIERS IN NEUROLOGY
(2023)
Article
Clinical Neurology
Jennifer Goettsche, Nils Schweingruber, Julian Christopher Groth, Christian Gerloff, Manfred Westphal, Patrick Czorlich
Summary: The study investigated the safety and clinical effects of switching from intravenous to oral nimodipine therapy in patients with aneurysmal subarachnoid hemorrhage. Results showed that the switch was not associated with adverse events or significant increases in blood flow velocities.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Ying Chen, Lijuan Wang, Jie Zhang, Sibo Wang, Yajie Qi, Jie Cao, Yingqi Xing
Summary: This study aimed to explore the use of QEEG and TCD for evaluating patients with ASBH. The results showed that QEEG can effectively predict 90-day mortality, while TCD cannot.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Critical Care Medicine
Carolina Rouanet, Feres Chaddad, Flavio Freitas, Maramelia Miranda, Natalia Vasconcellos, Raul Valiente, Susanne Muehlschlegel, Gisele Sampaio Silva
Summary: This study aimed to understand the impact of hypertension induction and inotropic therapy on cerebral hemodynamics in DCI patients. TCD analysis was conducted on patients receiving NE and milrinone treatment, revealing that milrinone effectively reduces cerebral blood flow velocity, with both treatment strategies leading to clinical improvement.
NEUROCRITICAL CARE
(2022)
Article
Clinical Neurology
Yongwoo Kim, Amit Mehta, Reshmi Nair, Daniel R. Felbaum, Jeffrey C. Mai, Rocco A. Armonda, Jason J. Chang
Summary: This study introduces a new marker, the hyperemia index (HI), calculated as the bilateral extracranial internal carotid artery mean flow velocity (MFV) divided by initial flow velocity. Results show that lower HI is associated with a higher likelihood of vasospasm and delayed cerebral ischemia (DCI). HI <1.2 may serve as a useful transcranial Doppler (TCD) parameter to indicate vasospasm and DCI when elevated MFV is observed or when transtemporal windows are inadequate.
JOURNAL OF NEUROIMAGING
(2023)
Review
Clinical Neurology
Carla Bittencourt Rynkowski, Juliana Caldas
Summary: This article summarizes ten crucial applications of cerebral ultrasonography in the evaluation and management of neurocritical patients. It highlights the evolution of cerebral ultrasonography as an imaging modality for brain parenchyma and emphasizes its importance among medical care staff.
FRONTIERS IN NEUROLOGY
(2022)
Article
Critical Care Medicine
Aurore Rodrigues, Virginie Tarazona, Alexandre Ladoux, Pierre Etienne Leblanc, Anatole Harrois, Bernard Vigue, Jacques Duranteau
Summary: CE-TCCD provides better visualization of intracranial arteries in patients with aSAH, especially in the middle cerebral arteries, anterior cerebral arteries, and posterior cerebral arteries compared to TCCD. The accuracy of CE-TCCD in screening severe MCA vasospasm is similar to TCCD. CE-TCCD is an alternative tool for monitoring patients with aSAH, particularly those without a temporal bone window for ultrasound.
NEUROCRITICAL CARE
(2022)
Article
Critical Care Medicine
Samuel B. Snider, Ibrahim Migdady, Sarah L. LaRose, Morgan E. Mckeown, Robert W. Regenhardt, Pui Man Rosalind Lai, Henrikas Vaitkevicius, Rose Du
Summary: This study investigated the association between TCD-measured vasospasm severity and cerebral infarction after aSAH, identifying optimal time/severity thresholds for predicting cerebral infarction. The results showed that TCD-measured vasospasm severity is associated with an increased risk of cerebral infarction, with specific time/severity cutoffs providing high negative predictive values.
NEUROCRITICAL CARE
(2022)
Article
Multidisciplinary Sciences
Fabiano Moulin de Moraes, Erica Navarro Borba Adissy, Eva Rocha, Felipe Chaves Duarte Barros, Flavio Geraldo Rezende Freitas, Maramelia Miranda, Raul Alberto Valiente, Joao Brainer Clares de Andrade, Feres Eduardo Aparecido Chaddad-Neto, Gisele Sampaio Silva
Summary: This study aims to evaluate four noninvasive methods for diagnosing intracranial hypertension. The results show a significant statistical correlation between noninvasive methods and invasive intracranial pressure, indicating an acceptable diagnostic ability. The combination of transcranial Doppler and wave morphology monitor may further enhance the diagnostic ability of noninvasive methods.
SCIENTIFIC REPORTS
(2023)
Article
Clinical Neurology
Qiuping Li, Yang Hua, Jiabin Liu, Fubo Zhou, Liyong Du, Jingzhi Li, Qing Li, Liqun Jiao
Summary: This study found that intraoperative TCD monitoring can help predict CHS after CEA at an early stage. The MCAV% values of CHS patients were significantly higher than non-CHS patients, and these values showed good accuracy in identifying CHS. Intraoperative TCD hemodynamic parameters play an important role in predicting CHS.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Qiuping Li, Yang Hua, Jiabin Liu, Fubo Zhou, Liyong Du, Jingzhi Li, Qing Li, Liqun Jiao
Summary: This study found that intraoperative transcranial Doppler (TCD) monitoring can help predict cerebral hyperperfusion syndrome (CHS) after carotid endarterectomy (CEA) at an early stage.
WORLD NEUROSURGERY
(2022)