Phosphate Binders Prevent Phosphate-Induced Cellular Senescence of Vascular Smooth Muscle Cells and Vascular Calcification in a Modified, Adenine-Based Uremic Rat Model

Direct, Acute Effects of Klotho and FGF23 on Vascular Smooth Muscle and Endothelium

(2014) Isabelle Six et al.   PLoS One

A Comparison of the Long-Term Effects of Lanthanum Carbonate and Calcium Carbonate on the Course of Chronic Renal Failure in Rats with Adriamycin-Induced Nephropathy

(2014) Tsuyoshi Takashima et al.   PLoS One

Macrophage-Derived Matrix Vesicles

(2013) Sophie E. P. New et al.   CIRCULATION RESEARCH

A Comparison of Calcium to Zoledronic Acid for Improvement of Cortical Bone in an Animal Model of CKD

(2013) Sharon M Moe et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Effect of a magnesium-based phosphate binder on medial calcification in a rat model of uremia

(2013) Tineke M. De Schutter et al.   KIDNEY INTERNATIONAL

Fibroblast growth factor 23 accelerates phosphate-induced vascular calcification in the absence of Klotho deficiency

(2013) Rika Jimbo et al.   KIDNEY INTERNATIONAL

High phosphate feeding induced arterial medial calcification in uremic rats: Roles of Lanthanum carbonate on protecting vasculature

(2013) Che Yu et al.   LIFE SCIENCES

Mortality in Kidney Disease Patients Treated with Phosphate Binders: A Randomized Study

(2012) B. Di Iorio et al.   Clinical Journal of the American Society of Nephrology

Effects of Sevelamer on HbA1c, Inflammation, and Advanced Glycation End Products in Diabetic Kidney Disease

(2012) H. Vlassara et al.   Clinical Journal of the American Society of Nephrology

Calcium Deficiency Reduces Circulating Levels of FGF23

(2012) M. E. Rodriguez-Ortiz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activation of nuclear factor-kappa B accelerates vascular calcification by inhibiting ankylosis protein homolog expression

(2012) Gexin Zhao et al.   KIDNEY INTERNATIONAL

Vitamin D receptor activators inhibit vascular smooth muscle cell mineralization induced by phosphate and TNF- 

(2012) Y. Aoshima et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Out of control: accelerated aging in uremia

(2012) J. P. Kooman et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Sirtuin 1 Retards Hyperphosphatemia-Induced Calcification of Vascular Smooth Muscle Cells

(2011) Aya Takemura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitochondrial Oxidative Stress in Aortic Stiffening With Age

(2011) Rui-Hai Zhou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fetuin-A Regulation of Calcified Matrix Metabolism

(2011) Willi Jahnen-Dechent et al.   CIRCULATION RESEARCH

Arterial Calcification in Chronic Kidney Disease: Key Roles for Calcium and Phosphate

(2011) Catherine M. Shanahan et al.   CIRCULATION RESEARCH

Multicenter prospective randomized, double-blind comparative study between lanthanum carbonate and calcium carbonate as phosphate binders in Japanese hemodialysis patients with hyperphosphatemia

(2011) T. Shigematsu et al.   CLINICAL NEPHROLOGY

The antioxidant tempol ameliorates arterial medial calcification in uremic rats: Important role of oxidative stress in the pathogenesis of vascular calcification in chronic kidney disease

(2011) Shunsuke Yamada et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1  Secretion through the NLRP3 Inflammasome In Vitro

(2011) B. Pazar et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial reactive oxygen species promote p65 nuclear translocation mediating high-phosphate-induced vascular calcification in vitro and in vivo

(2011) Ming-Ming Zhao et al.   KIDNEY INTERNATIONAL

The Phosphate Binder Equivalent Dose

(2011) John T. Daugirdas et al.   SEMINARS IN DIALYSIS

Vascular Calcification in Animal Models of CKD: A Review

(2010) Navid Shobeiri et al.   AMERICAN JOURNAL OF NEPHROLOGY

Indoxyl sulfate, a uremic toxin, promotes cell senescence in aorta of hypertensive rats

(2010) Ayinuer Adijiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sevelamer Carbonate Reduces Inflammation and Endotoxemia in an Animal Model of Uremia

(2010) Aline B. Hauser et al.   BLOOD PURIFICATION

Pathophysiology of vascular calcification: Pivotal role of cellular senescence in vascular smooth muscle cells

(2010) D.G.A. Burton et al.   EXPERIMENTAL GERONTOLOGY

Cell Senescence in the Aging Kidney

(2010) H. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition

(2009) Ritsuko Nakano-Kurimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Microarray analysis of senescent vascular smooth muscle cells: A link to atherosclerosis and vascular calcification

(2009) Dominick G.A. Burton et al.   EXPERIMENTAL GERONTOLOGY

Chronic Mineral Dysregulation Promotes Vascular Smooth Muscle Cell Adaptation and Extracellular Matrix Calcification

(2009) R. C. Shroff et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Endotoxin-binding affinity of sevelamer: a potential novel anti-inflammatory mechanism

(2009) Phyllis P. Sun et al.   KIDNEY INTERNATIONAL

Adequate phosphate binding with lanthanum carbonate attenuates arterial calcification in chronic renal failure rats

(2009) E. Neven et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

A 1-Year Randomized Trial of Calcium Acetate Versus Sevelamer on Progression of Coronary Artery Calcification in Hemodialysis Patients With Comparable Lipid Control: The Calcium Acetate Renagel Evaluation-2 (CARE-2) Study

(2008) Wajeh Qunibi et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Age-related medial elastocalcinosis in arteries: mechanisms, animal models, and physiological consequences

(2008) Jeffrey Atkinson   JOURNAL OF APPLIED PHYSIOLOGY

Cinacalcet suppresses calcification of the aorta and heart in uremic rats

(2008) Takehisa Kawata et al.   KIDNEY INTERNATIONAL

A rat model of chronic kidney disease-mineral bone disorder

(2008) Sharon M. Moe et al.   KIDNEY INTERNATIONAL