Article
Nursing
Lydia A. Bertschi
Summary: This article discusses the meaning and function of complete blood count components and emphasizes the important pathophysiological evidence they provide. It also highlights the use of composite patient scenarios to assist nurses in recognizing key findings that can inform their plan of care and improve patient outcomes.
AMERICAN JOURNAL OF NURSING
(2021)
Article
Medicine, General & Internal
Yusi Hua, Ruoran Wang, Jie Yang, Xiaofeng Ou
Summary: This study investigated the predictive value of platelet count at admission for mortality in sepsis patients. The results showed that platelet count at admission was negatively correlated with mortality, with lower platelet count indicating higher risk of death. Age and lactate level were also identified as independent risk factors for mortality in sepsis patients.
Review
Medicine, General & Internal
Domenico Alvaro, Nicola Caporaso, Edoardo Giovanni Giannini, Angelo Iacobellis, Mariacristina Morelli, Pierluigi Toniutto, Francesco Violi
Summary: Studies suggest that severe thrombocytopenia may predict bleeding risk following invasive procedures such as liver biopsy, dental extractions, percutaneous ablation of liver tumors, and endoscopic polypectomy. Current literature does not provide definitive conclusions on the appropriate target platelet counts to improve bleeding risk in cirrhotic patients undergoing invasive procedures, and there is huge variability in the use of prophylactic platelet transfusions.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Gastroenterology & Hepatology
Haotang Ren, Hai Li, Guohong Deng, Xianbo Wang, Xin Zheng, Yan Huang, Jinjun Chen, Zhongji Meng, Yanhang Gao, Zhiping Qian, Feng Liu, Xiaobo Lu, Jia Shang, Shaoyang Wang, Shan Yin, Wenting Tan, Yixin Hou, Shue Xiong, Liyuan Long, Beiling Li, Sen Luo, Weituo Zhang, Yu Shi
Summary: This study investigated the prevalence and severity of anemia in patients with cirrhosis and acute decompensation or liver injury, as well as the impact of anemia on short-term and long-term outcomes. The results showed that severe anemia was associated with poor prognosis in these patients.
ANNALS OF HEPATOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Antoine Rauch, Annabelle Dupont, Mickael Rosa, Maximilien Desvages, Christina Le Tanno, Johan Abdoul, Melusine Didelot, Alexandre Ung, Richard Ruez, Emmanuelle Jeanpierre, Melanie Daniel, Delphine Corseaux, Hugues Spillemaeker, Julien Labreuche, Benedicte Pradines, Natacha Rousse, Peter J. Lenting, Mouhamed D. Moussa, Andre Vincentelli, Jean-Claude Bordet, Bart Staels, Flavien Vincent, Cecile V. Denis, Eric Van Belle, Caterina Casari, Sophie Susen
Summary: Thrombocytopenia is consistently observed in ECMO patients, with a time-dependent decrease in platelet count, GP Ib alpha shedding, and increased soluble GP Ib alpha levels. Shedding of GP Ib alpha is dependent on rheological conditions, with higher rates at high-flow speeds.
CIRCULATION RESEARCH
(2023)
Article
Pediatrics
Hanna Wielinska-Wisniewska, Jan K. Nowak, Michal Dabrowski, Paula Szydlowska, Mariusz Szczepanik, Katarzyna Cichocka, Patrycja Krzyzanowska-Jankowska, Jaroslaw Walkowiak
Summary: The study found that capillary blood complete blood count is reliable in detecting leukocytosis in children with acute gastroenteritis, with high concordance with venous blood measurements.
FRONTIERS IN PEDIATRICS
(2021)
Article
Multidisciplinary Sciences
Kevin DeSpain, Charles R. Rosenfeld, Ryan Huebinger, Xiaofu Wang, Jayson W. Jay, Ravi S. Radhakrishnan, Steven E. Wolf, Juquan Song
Summary: Severe burns result in decreased sensitivity of carotid arteries to norepinephrine and angiotensin II, as well as reduced relaxation responses to acetylcholine within 6 hours post-burn. Burn injuries also lead to increased carotid artery wall thickness and collagen expression in the tunica media.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Harapan Parlindungan Ringoringo
Summary: This study aims to determine the prevalence of iron deficiency anemia (IDA), identify the influencing factors, and establish reference ranges for complete blood count (CBC) and reticulocyte parameters in infants aged 9-11 months in Indonesia. The prevalence of IDA in the study population was found to be 32%.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2022)
Article
Microbiology
Zhongwei Zhang, Xue Hu, Qunqun Jiang, Wenjia Hu, Anling Li, Liping Deng, Yong Xiong
Summary: This study investigated the clinical characteristics and outcomes of acute kidney injury (AKI) in patients with severe fever with thrombocytopenia syndrome (SFTS). The results showed that AKI is associated with poor outcomes in SFTS patients, especially those in stage 2 or 3 AKI, who have higher mortality rates. Early identification and timely treatment of AKI in SFTS patients are important.
FRONTIERS IN MICROBIOLOGY
(2023)
Review
Medicine, General & Internal
Luisa Agnello, Rosaria Vincenza Giglio, Giulia Bivona, Concetta Scazzone, Caterina Maria Gambino, Alessandro Iacona, Anna Maria Ciaccio, Bruna Lo Sasso, Marcello Ciaccio
Summary: Complete blood count is a valuable test that provides a wealth of information on individual health status, guiding clinicians to early-identify patients at high risk of sepsis and predict adverse outcomes. It is cheap, easy-to-perform, and available in all wards, showcasing several advantages over other investigated biomarkers for sepsis.
Article
Pediatrics
Huifeng Fan, Ying Cui, Xuehua Xu, Dongwei Zhang, Diyuan Yang, Li Huang, Tao Ding, Gen Lu
Summary: A classification model using complete blood count was developed to predict severity in pediatric patients with HAdV lower respiratory tract infections. The monocyte ratio was found to be the most obvious difference between mild and severe cases at onset and could be used as an early marker for accurate prediction of severity. A model using four risk factors (monocyte ratio, hematocrit, red blood cell count, and platelet count) was constructed to accurately assess the risk of severe cases in the early stages of HAdV lower respiratory tract infections.
FRONTIERS IN PEDIATRICS
(2022)
Article
Multidisciplinary Sciences
Mehak Narjis, Mamoona Noreen, Sher Zaman Safi, Naureen Ehsan Ilahi, Suliman Yousef Alomar, Afrah Fahad Alkhuriji
Summary: The study suggests that complete blood count can serve as an indicator for the development of type II diabetes complications, with a correlation between higher leukocyte counts and uncontrolled diabetes. This factor may be related to chronic inflammation and the progression of diabetes-related complications.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2021)
Article
Health Care Sciences & Services
Alhasan Alsalman, Mohammad A. Al-Mterin, Ala Abu-Dayeh, Ferial Alloush, Khaled Murshed, Eyad Elkord
Summary: This study found associations between certain CBC parameters and colorectal cancer prognosis, such as red cell distribution width, platelet count, and mean platelet volume. Additionally, differences in white blood cells, monocytes, and mean platelet volume were observed in patients with different disease stages. Tumor location also influenced levels of certain CBC parameters.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Cell Biology
Tobias Schupp, Kathrin Weidner, Jonas Rusnak, Schanas Jawhar, Jan Forner, Floriana Dulatahu, Lea Marie Brueck, Ursula Hoffmann, Maximilian Kittel, Thomas Bertsch, Ibrahim Akin, Michael Behnes
Summary: Thrombocytopenia and platelet decline are associated with an increased risk of 30-day all-cause mortality in patients admitted with sepsis or septic shock.
Article
Critical Care Medicine
Anna Olszewski, Amber Yanes, Jessica Stafford, David G. Greenhalgh, Tina L. Palmieri, Soman Sen, Nam Tran
JOURNAL OF BURN CARE & RESEARCH
(2016)
Article
Critical Care Medicine
Zachary Godwin, Kelly Lima, David Greenhalgh, Tina Palmieri, Soman Sen, Nam K. Tran
JOURNAL OF BURN CARE & RESEARCH
(2016)
Article
Pharmacology & Pharmacy
Sarah M. Becker, Kathleen M. Job, Kelly Lima, Ty J. Forbes, Jadon Wagstaff, Nam K. Tran, Catherine M. Sherwin, Douglas S. Nelson, Michael D. Johnson, Joseph E. Rower
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
(2019)
Article
Critical Care Medicine
Kristin N. Grimsrud, Xenia Ivanova, Catherine M. Sherwin, Tina L. Palmieri, Nam K. Tran
JOURNAL OF BURN CARE & RESEARCH
(2019)
Article
Medicine, Research & Experimental
Daniel K. Nishijima, John VanBuren, Hilary A. Hewes, Sage R. Myers, Rachel M. Stanley, P. David Adelson, Sarah E. Barnhard, Matthew Bobinski, Simona Ghetti, James F. Holmes, Ian Roberts, Walton O. Schalick, Nam K. Tran, Leah S. Tzimenatos, J. Michael Dean, Nathan Kuppermann
Article
Critical Care Medicine
Nam K. Tran, Soman Sen, Tina L. Palmieri, Kelly Lima, Stephanie Falwell, Jeffery Wajda, Hooman H. Rashidi
Article
Medical Laboratory Technology
Martha E. Lyon, Oliver A. S. Lyon, Nam K. Tran, Jeffrey A. DuBois, Andrew W. Lyon
CLINICAL BIOCHEMISTRY
(2019)
Review
Medical Laboratory Technology
Raffick Bowen, Raul Benavides, Jessica M. Colon-Franco, Brooke M. Katzman, Alagarraju Muthukumar, Hossein Sadrzadeh, Joely Straseski, Ursula Klause, Nam Tran
CLINICAL BIOCHEMISTRY
(2019)
Article
Multidisciplinary Sciences
Hooman H. Rashidi, Soman Sen, Tina L. Palmieri, Thomas Blackmon, Jeffery Wajda, Nam K. Tran
SCIENTIFIC REPORTS
(2020)
Article
Emergency Medicine
James S. Ford, Tasleem Chechi, Michella Otmar, Melissa Baker, Sarah Waldman, Brittany Morgan, David Tan, Nam K. Tran, Larissa May
Summary: The study demonstrates that utilizing an electronic health record alert to prompt syphilis testing in patients undergoing gonorrhoea/chlamydia testing can increase the number of syphilis tests and diagnoses while potentially reducing clinician bias in testing.
EMERGENCY MEDICINE JOURNAL
(2022)
Article
Emergency Medicine
Daniel K. Nishijima, John M. VanBuren, Seth W. Linakis, Hilary A. Hewes, Sage R. Myers, Nam K. Tran, Simona Ghetti, Matthew Bobinski, P. David Adelson, Ian Roberts, James F. Holmes, Walton O. Schalick, J. Michael Dean, T. Charles Casper, Nathan Kuppermann
Summary: This study assessed the feasibility of using the antifibrinolytic drug tranexamic acid (TXA) to treat hemorrhagic brain and/or torso injuries in severely injured children. The trial confirmed the possibility of conducting a large-scale trial using federal exception from informed consent (EFIC) procedures to evaluate the efficacy of TXA in children.
ACADEMIC EMERGENCY MEDICINE
(2022)
Article
Multidisciplinary Sciences
Hooman H. Rashidi, John Pepper, Taylor Howard, Karina Klein, Larissa May, Samer Albahra, Brett Phinney, Michelle R. Salemi, Nam K. Tran
Summary: The study aims to compare the performance of two commercial automated machine learning platforms in COVID-19 mass spectrometry analysis. The results demonstrate the robustness of machine learning models against SARS-CoV-2 variants on different platforms and highlight similarities and differences in producing predictive algorithms.
Review
Pathology
Hooman H. Rashidi, Nam K. Tran, Elham Vali Betts, Lydia P. Howell, Ralph Green
ACADEMIC PATHOLOGY
(2019)
Article
Critical Care Medicine
Jeffrey Anton DuBois, Robbert Jan Slingerland, Marion Foldcert, Alain Roman, Nam Khoa Tran, William Clarke, David Alan Sartori, Tina Louise Palmieri, Andrei Malic, Martha Elizabeth Lyon, Andrew William Lyon
CRITICAL CARE MEDICINE
(2017)