Article
Dermatology
D. Krasowska, T. Gambichler, C. Cortes, A. Horev, N. Compagno, S. S. Dahale, P. Papanastasiou, D. Keefe
Summary: This study investigated the long-term (104 weeks) efficacy and safety of secukinumab in pediatric patients with severe chronic plaque psoriasis. The results showed that secukinumab demonstrated sustained efficacy and a favorable safety profile up to 2 years of treatment.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Article
Health Care Sciences & Services
Yuanjie Pang, Yuting Han, Canqing Yu, Christiana Kartsonaki, Yu Guo, Yiping Chen, Ling Yang, Huaidong Du, Wei Hou, Danile Schmidt, Rebecca Stevens, Junshi Chen, Zhengming Chen, Jun Lv, Liming Li
Summary: This study assessed the associations between lifestyle factors and the progression of chronic liver disease. It found that high-risk lifestyle factors played a key role in all stages of disease transition, from healthy to chronic liver disease, subsequently to cardiometabolic disease, and then to death, with varying magnitudes of associations.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2022)
Article
Infectious Diseases
Vanesa Seery, Silvina Raiden, Juan Martin Gomez Penedo, Mauricio Borda, Largion Herrera, Macarena Uranga, Maria Marco del Pont, Carina Chirino, Constanza Erramuspe, Laura Silvana Alvarez, Melisa Lenoir, Laura Daniela Morales, Carolina Davenport, Soledad Huespe Auchter, Liliana Monsalvo, Laura Sastoque, Magali Gavazzi, Constanza Russo, Ines Sananez, Maria de los Angeles Pando, Natalia Laufer, Roberto Muinos, Fernando Ferrero, Jorge Geffner, Lourdes Arruvito
Summary: This study investigated the long-term symptoms of COVID-19 in Argentinian children and found that one-third of children experienced persistent symptoms. Older age, symptomatic infection, and comorbidities were identified as risk factors for long COVID-19.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Pediatrics
Dorine M. Borensztajn, Nienke N. Hagedoorn, Enitan D. Carrol, Ulrich von Both, Marieke Emonts, Michiel van der Flier, Ronald de Groot, Jethro Herberg, Benno Kohlmaier, Michael Levin, Emma Lim, Ian K. Maconochie, Federico Martinon-Torres, Ruud G. Nijman, Marko Pokorn, Irene Rivero-Calle, Maria Tsolia, Fabian J. S. van der Velden, Clementien Vermont, Dace Zavadska, Werner Zenz, Joany M. Zachariasse, Henriette A. Moll
Summary: Children with comorbidities are at a higher risk of bacterial infections, often requiring PICU admission and life-saving interventions. They show more severe illness and are diagnosed with serious conditions more frequently.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Public, Environmental & Occupational Health
Dominika Bhatia, Rinku Sutradhar, Jill Tinmouth, Simron Singh, Cindy Lau, Lorraine L. Lipscombe
Summary: Chronic comorbidities pose barriers to periodic guideline-recommended colorectal cancer screening, resulting in significantly lower testing rates for individuals with various comorbidities. The presence of both medical and mental comorbidities is associated with even lower testing rates than having either type of comorbidity alone.
PREVENTIVE MEDICINE
(2021)
Article
Computer Science, Artificial Intelligence
Shahadat Uddin, Shangzhou Wang, Haohui Lu, Arif Khan, Farshid Hajati, Matloob Khushi
Summary: The prevalence of chronic disease comorbidity and multimorbidity is a significant health issue worldwide. This study used machine learning and network analytics to predict major chronic disease comorbidity and multimorbidity. Extreme Gradient Boosting and Convolutional Neural Networks showed the highest accuracy in prediction. The number of episodes from the patient trajectory and transitivity in patient networks were found to be the most important features.
EXPERT SYSTEMS WITH APPLICATIONS
(2022)
Review
Medicine, General & Internal
Natalia Dryjanska, Katarzyna Kilis-Pstrusinska
Summary: Depression is a significant health problem, especially among children and adolescents, and it is more prevalent in patients with chronic diseases such as chronic kidney disease (CKD). This review discusses the high risk of developing depression in adolescents and females, and the impact of depression on the quality of life of children and adolescents with CKD. The stage of the disease, age of CKD diagnosis, and type of treatment significantly affect the health-related quality of life (HRQoL) and caregiver burden. Screening for depression is recommended for CKD patients, and transdiagnostic tools should be used for symptom alleviation. Preventative strategies should be considered for children at risk of developing depression.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Education, Special
Ting-Yi Lee, Shih-Jen Tsai, Tzeng-Ji Chen, Mu-Hong Chen
Summary: Studies have shown a significant association between autism spectrum disorder (ASD) and migraine, with individuals with ASD having a higher risk of developing migraine in the future compared to those without ASD, independent of medical and psychiatric comorbidities. Further research is needed to explore the underlying mechanisms of this association.
RESEARCH IN AUTISM SPECTRUM DISORDERS
(2021)
Article
Psychology, Developmental
Mehmet Akif Akinci, Bahadir Turan, Ibrahim Selcuk Esin, Onur Burak Dursun
Summary: This study estimated the prevalence of hoarding disorder (HD) in children and adolescents using a two-stage epidemiological research approach, finding a prevalence rate of 0.98%. The study also identified factors associated with the disorder, such as female sex and the presence of any psychopathology, and found that more than half of children with HD also had a comorbid psychiatric disorder.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2022)
Article
Immunology
Anne L. Wyllie, Joshua L. Warren, Gili Regev-Yochay, Noga Givon-Lavi, Ron Dagan, Daniel M. Weinberger
Summary: The frequency of serotypes causing IPD differs between adults and children, as well as between older and younger adults and adults with and without comorbidities. Older children, rather than infants, were found to have a better correlation with the serotype-specific IPD patterns in adults, indicating they may play a more influential role in disease patterns. These findings could help optimize vaccination strategies to reduce disease burden across different age groups.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Psychology, Developmental
Bridget W. Mahony, Danni Tu, Srishti Rau, Siyuan Liu, Francois M. Lalonde, Aaron F. Alexander-Bloch, Theodore D. Satterthwaite, Russell T. Shinohara, Dani S. Bassett, Michael P. Milham, Armin Raznahan
Summary: This study aims to analyze the correlations between cognitive ability and psychopathology. The research fills the gap by focusing on a diverse care-seeking population and quantifying the relationships between full-scale IQ and multiple dimensions of psychopathology. The findings reveal the differential coupling between psychopathology dimensions as a function of IQ.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Multidisciplinary
Michaela Junghaenel, Ann-Kathrin Thoene, Christina Dose, Dieter Breuer, Anja Goertz-Dorten, Manfred Doepfner
Summary: The objective of this study is to understand the structure of anxiety and depressive symptoms by using latent factor analysis and network analysis together. The study included 743 children and adolescents seeking outpatient psychotherapy. The results showed a complex relationship between anxiety and depressive symptoms, with stronger associations within each domain than between the two domains. Pain, suicidal thoughts, irritability, and fear of adults were identified as bridge symptoms.
CURRENT PSYCHOLOGY
(2023)
Article
Pediatrics
Emma E. Berkelbach van der Sprenkel, Sanne L. Nijhof, Geertje W. Dalmeijer, N. Charlotte Onland-Moret, Simone A. de Roos, Heidi M. B. Lesscher, Elise M. van de Putte, Cornelis K. van der Ent, Catrin Finkenauer, Gonneke W. J. M. Stevens
Summary: This study examined the psychosocial functioning of adolescents with chronic diseases and their family members, using data from the Dutch 2013 HBSC survey. Findings suggest that chronically diseased adolescents experience impaired psychosocial functioning across various life domains, and healthy adolescents with chronically diseased family members also show significant differences in psychosocial outcomes. Additionally, healthy adolescents with chronically diseased family members reported more positive outcomes compared to those adolescents who had a chronic disease themselves.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Surgery
Kevin J. Blair, Fanny N. Dissak-Delon, Rasheedat Oke, Melissa Carvalho, Alan Hubbard, Mbiarikai Mbianyor, Georges Alain Etoundi-Mballa, Thompson Kinge, Louis Richard Njock, Daniel N. Nkusu, Jean-Gustave Tsiagadigui, Rochelle A. Dicker, Alain Chichom-Mefire, Catherine Juillard, S. Ariane Christie
Summary: This study estimated a high prevalence of known chronic disease comorbidities among injured patients in Cameroon, and found that patients with known chronic diseases had higher mortality and admission rates. Integrating chronic disease screening with injury care may help improve outcomes for patients in Cameroon, despite underdiagnosis.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Pediatrics
Ozge Azman, Elvira Mauz, Matthias Reitzle, Raimund Geene, Heike Hoelling, Petra Rattay
Summary: This study aimed to investigate the association between parenting style and the mental health of children and adolescents aged 11-17 years. It found significantly higher mean scores for demanding-controlling and emotional distancing parenting styles. These associations persisted after adjustment and did not vary by socioeconomic or migration status, suggesting that parenting behavior is an important predictor of children's and adolescents' mental health.
