Article
Spectroscopy
Baowen Zhang, Lianfang Chen, Maosen Zhang, Caixia Deng, Xiupei Yang
Summary: In this study, silver-doped gold-based bimetallic nanoclusters were synthesized and demonstrated as an effective and reliable sensor system for the sensitive detection of cysteine.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Biotechnology & Applied Microbiology
Si Yang, Chenxi Li, Hongyan Zhan, Rong Liu, Wenliang Chen, Xiaoli Wang, Kexin Xu
Summary: In this study, a label-free fluorescent biosensor for the detection of tetracycline (TET) was developed using specific aptamer-templated silver nanoclusters (AgNCs). The binding of TET to the aptamer led to a conformational change, resulting in the transformation of AgNCs into larger silver nanoparticles (AgNPs) and a decrease in fluorescence. The proposed biosensor exhibited high sensitivity and selectivity for TET detection in milk, with a limit of detection of 11.46 ng/mL and a linear range of 20 ng/mL-10 g/mL. These findings demonstrate the potential of the biosensor for quantitative determination of TET in food samples and expand the application of DNA-AgNCs in related fields.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Chemistry, Analytical
Yuliang Cheng, Guowen Li, Xiufang Huang, Zhijuan Qian, Chifang Peng
Summary: A label-free fluorescent detection method for glyphosate based on DNA-Ag NCs and a Cu2+-ion-modulated strategy was developed, achieving ultrasensitive detection of glyphosate. The method showed a linear response in the range of 1.0-50 ng/mL with a LOD of 0.2 ng/mL, demonstrating high application potential for glyphosate detection.
Article
Chemistry, Analytical
S. Swathy, Goldamol S. Pallam, K. Girish Kumar
Summary: A tryptophan capped gold-silver bimetallic nanocluster based turn-off fluorescence sensor was developed for the rapid determination of histamine. The sensor parameters were optimized and fluorescence quenching of the nanoclusters was observed with the addition of histamine. The sensor exhibited good sensitivity with a linear range of 8.5 x 10-5 M to 4.0 x 10-6 M and a limit of detection of 9.0 x 10-7 M. Spike recovery analysis in synthetic physiological fluids confirmed the practical utility of the sensor.
Article
Chemistry, Applied
Mengting Guan, Yue Guo, Xiaoxia Yan, Xiaojing Si, Xitian Peng, Yunyi Lei, Xia Shen, Liqiang Luo, Haibo He
Summary: In this study, a fluorescence on-off system based on glutathione-gold nanoclusters (GSH-Au NCs) and silver ions (Ag+) was developed for sensitive monitoring of carbendazim (CBZ) residues in fruit samples. The system showed superior selectivity towards CBZ and had a low detection limit for CBZ determination in apple and orange juices.
Article
Chemistry, Analytical
Ning Lian, Yaheng Zhang, Dan Liu, Jianghong Tang, Haiyan Wu
Summary: Copper nanoclusters were synthesized using excess cysteine and successfully used to detect quinolones in a cost-effective, highly selective, and sensitive sensor. The sensor showed strong potential in detecting target fluorescent substances in tablets and human urine with a wide linear range and low detection limits.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Jingjing Gao, Hui Xu, Faju Hou, Shengxiao Zhang
Summary: A novel DNA-silver nanocluster probe was developed for detecting breast tumor-related mRNA markers, with a low detection limit and linear range, and the ability to accurately distinguish single-base mismatches.
ANALYTICAL SCIENCES
(2022)
Article
Materials Science, Multidisciplinary
Yu Chen, Ting Feng, Li Chen, Yiming Gao, Junwei Di
Summary: A signal-on fluorescence method using BSA-Ag30NCs as sensing probe was developed for determination of hydrogen peroxide (H2O2) and glucose, with linear calibration curves obtained for both substances within specific concentration ranges. The enhancement of fluorescence intensity was found to be linearly related to the concentration of each substance, with satisfactory results achieved in the detection of glucose in human serum samples using this method.
Article
Chemistry, Physical
Zhi-feng Cai, Chen-hua Deng, Jiao Wang, Yao Zuo, Jing-long Wu, Xiao-peng Wang, Tian-zhi Lv, Yuan-yuan Wang, Deng-yun Feng, Jie Zhao, Cai-feng Zhang, Ji-ming Zhang
Summary: Aloin is a natural medicine with various functions, and a simple method using fluorescence for its detection has been proposed in this study, showing high sensitivity and accuracy in detecting aloin.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Materials Science, Multidisciplinary
Liyun Yang, Yuanping Liao, Zhiqiang Zhou
Summary: In this study, a fluorescent probe for detecting glutathione (GSH) was developed by capping 11-mercaptoundecanoic acid (11-MUA) on gold nanoclusters (AuNCs) and combining them with copper ions (Cu2+). The fluorescence of AuNCs was quenched in the presence of Cu2+, and the addition of GSH resulted in the detachment of Cu2+ and fluorescence recovery. The detection range of GSH was 0.05-5 μM with a detection limit of 33.3 nM. The proposed sensor showed potential applicability for accurate GSH detection in commercial drugs and cell lysate.
Article
Chemistry, Analytical
Zhenzhen Jia, Kangsheng Tu, Qiuran Xu, Wenhui Gao, Cui Liu, Biyun Fang, Mingzhen Zhang
Summary: A universal sensing platform based on DNA-Ag NC was developed for sensitive detection of disease-associated nucleic acids, showing excellent reproducibility, selectivity, and potential applications in human serum samples. The platform was successfully applied for miR-362 and HIV-related DNA detection, achieving low detection limits of 6.5 nM and 1.7 nM, respectively.
ANALYTICA CHIMICA ACTA
(2021)
Article
Biochemistry & Molecular Biology
Haoyuan Li, Hongxiang Zhu, Zongyan Quan, Zhiping Chen, Lei Wang, Hui He
Summary: A novel bionic bifunctional cellulose nanocrystal (CNC)-based gold nanocluster probe was successfully constructed by growing gold nanoclusters on CNCs modified with a specific DNA sequence. The probe exhibited excellent fluorescence properties and stability, and could detect different pathological markers in cells.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Zheng-Fen Pu, Jun Peng, Qiu-Lin Wen, Yu Li, Jian Ling, Peng Liu, Qiu-E Cao
Summary: A new photocatalytic synthesis strategy was developed for the rapid preparation of BSA-Au nanoclusters with tunable fluorescence, which could be used for highly selective detection of silver ions. The silver ion not only acted as a photocatalyst to accelerate the formation of fluorescent Au nanoclusters, but also as a regulator to tune the fluorescence emission color of the BSA-Au nanoclusters. This method showed high selectivity for silver ion detection and had potential applications in environmental water sample analysis.
Article
Chemistry, Multidisciplinary
Jin Sakai, Sourav Biswas, Tsukasa Irie, Haruna Mabuchi, Taishu Sekine, Yoshiki Niihori, Saikat Das, Yuichi Negishi
Summary: Silver cluster-assembled materials (SCAMs) with molecular-level designability and unique photophysical properties have limited application scope due to their dissimilar structural architecture in different solvent media. In this study, two unprecedented luminescent SCAMs (TUS 1 and TUS 2) were synthesized, composed of an Ag-12 cluster core connected by quadridentate pyridine linkers. These materials exhibit exceptional fluorescence properties with high absolute quantum yield (QY) and excellent chemical stability in a wide range of solvent polarity. A highly sensitive assay for detecting Fe3+ in aqueous medium was developed, with promising detection limits comparable to the standard. The potential application of these materials in environmental monitoring and assessment was demonstrated through the detection of Fe3+ in real water samples.
Article
Optics
Zhifeng Cai, Ruitao Zhu, Shen Zhang, Liangliang Wu, Junhong Li, Suiyuan Huang, Xinru Ma
Summary: A novel fluorescence detection method based on Cu NCs was developed for determination of morin and temperature. The TA protected Cu NCs exhibited good water solubility and high photostability. This method showed excellent sensitivity and selectivity for morin detection and practicality in bovine serum samples.
JOURNAL OF LUMINESCENCE
(2021)
Article
Chemistry, Analytical
Gang Qu, Yuxin Zhao, Qiaoli Zhang, Jina Wu, Xiaosen Li, Yang Yang, Shilei Liu
Summary: In this study, magnetic mesoporous materials combined with real-time in situ mass spectrometry were used for the high-throughput detection of hydrolyzed products of organophosphorus nerve agents. The method showed good linearity, low limits of detection and quantification, and high extraction recoveries. The magnetic preparation method used was quick, cost-effective, rugged, and safe. The results demonstrated the potential of this method for rapid and efficient determination of the target analytes in environmental samples.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Anna Hildebrand, Mariam Merchant, Danny O'Hare
Summary: Substandard and falsified artemisinin derivatives in antimalarials have caused significant deaths and economic losses. This study evaluates the feasibility of voltammetric methods for identifying and quantifying artemether. The findings suggest that electrochemical analysis shows promise as a method for artemether identification and quantification.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Marx Osorio Araujo Pereira, Alvaro Ferreira Junior, Edson Silvio Batista Rodrigues, Helena Mulser, Giovanna Nascimento de Mello e Silva, Wallans Torres Pio dos Santos, Eric de Souza Gil
Summary: Brazilian spotted fever (BSF) is a serious and rapidly evolving disease. A new impedimetric immunosensor was developed for rapid diagnosis by measuring specific antibodies in plasma. The sensor demonstrated selectivity and accuracy, and has potential for important applications in diagnostic testing.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Kathrin Schilling, Ronald A. Glabonjat, Olgica Balac, Marta Galvez-Fernandez, Arce Domingo-Relloso, Vesna Slavkovich, Jeff Goldsmith, Miranda R. Jones, Tiffany R. Sanchez, Ana Navas-Acien
Summary: Analysis of trace elements in urine is an important tool for assessing exposures, diagnosing nutritional status, and guiding public health and healthcare intervention. This study provides a sensitive method for analyzing 18 elements in urine samples, using only 100 μL. The results show good accuracy and sensitivity of the method.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Mengya Li, Shijie Liu, Shiliang Guo, Dong Liang, Miaoyun Li, Yaodi Zhu, Lijun Zhao, Jong-Hoon Lee, Gaiming Zhao, Yangyang Ma, Yanxia Liu
Summary: In this study, a magnetic flow device was developed to purify spores in a culture medium system. The device used magnetic nanoparticles to absorb vegetative cells, separating them from the spores. The achieved purity of the collected spores was over 95%. The study also demonstrated a rapid quantitative detection method using Raman spectroscopy.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Wanqiong Liu, Zixuan Wu, Jianwei Peng, Zebin Xu, Yong Liang
Summary: Metal-organic frameworks (MOFs) are effective carriers for molecular imprinting, but their poor dispersibility in aqueous solution is a significant drawback. In this study, we have applied amphiphilic block copolymers and molecularly imprinted technology on MOFs to improve the hydrophilicity of molecularly imprinted fluorescent materials.
ANALYTICAL METHODS
(2024)