Influence of the Nuclear Membrane, Active Transport, and Cell Shape on the Hes1 and p53–Mdm2 Pathways: Insights from Spatio-temporal Modelling

A review of topotecan in combination chemotherapy for advanced cervical cancer

(2016) Charles Dunton   Therapeutics and Clinical Risk Management

The p53 response element and transcriptional repression

(2011) Bei Wang et al.   CELL CYCLE

Microtubule disruption targets HIF-1α mRNA to cytoplasmic P-bodies for translational repression

(2011) Marisa Carbonaro et al.   JOURNAL OF CELL BIOLOGY

Spatio-temporal modelling of the intracellular signalling pathway: The roles of diffusion, active transport, and cell geometry

(2011) Alan J. Terry et al.   JOURNAL OF THEORETICAL BIOLOGY

Dynamics of nonmembranous cell components: Role of active transport along microtubules

(2010) A. Yu. Lomakin et al.   BIOCHEMISTRY-MOSCOW

Molecular basis for specificity of nuclear import and prediction of nuclear localization

(2010) Mary Marfori et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Basal Dynamics of p53 Reveal Transcriptionally Attenuated Pulses in Cycling Cells

(2010) Alexander Loewer et al.   CELL

A spatial model of cellular molecular trafficking including active transport along microtubules

(2010) A. Cangiani et al.   JOURNAL OF THEORETICAL BIOLOGY

From structure to dynamics: Frequency tuning in the p53-Mdm2 network. II

(2010) Djomangan A. Ouattara et al.   JOURNAL OF THEORETICAL BIOLOGY

Spatio-temporal modelling of the Hes1 and p53-Mdm2 intracellular signalling pathways

(2010) Marc Sturrock et al.   JOURNAL OF THEORETICAL BIOLOGY

A model of yeast cell-cycle regulation based on multisite phosphorylation

(2010) Debashis Barik et al.   Molecular Systems Biology

Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin

(2009) Aurélien Bancaud et al.   EMBO JOURNAL

Crosstalk between p53 and nuclear factor-κB systems: pro- and anti-apoptotic functions of NF-κB

(2009) K. Puszynski et al.   IET Systems Biology

Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor

(2009) Harish Shankaran et al.   Molecular Systems Biology

Therapeutic Targeting of Nuclear Protein Import in Pathological Cell Conditions

(2009) M. N. Chahine et al.   PHARMACOLOGICAL REVIEWS

Exploring the roles of noise in the eukaryotic cell cycle

(2009) S. Kar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatio-Temporal Modelling of the p53–mdm2 Oscillatory System

(2009) K. E. Gordon et al.   Mathematical Modelling of Natural Phenomena

Computational Models of the Notch Network Elucidate Mechanisms of Context-dependent Signaling

(2009) Smita Agrawal et al.   PLoS Computational Biology

Stochastic Simulation of Enzyme-Catalyzed Reactions with Disparate Timescales

(2008) Debashis Barik et al.   BIOPHYSICAL JOURNAL

A review of imaging techniques for systems biology

(2008) Armen R Kherlopian et al.   BMC Systems Biology

Cell Shape and Negative Links in Regulatory Motifs Together Control Spatial Information Flow in Signaling Networks

(2008) Susana R. Neves et al.   CELL

Critical Role of Notch Signaling in Osteosarcoma Invasion and Metastasis

(2008) P. Zhang et al.   CLINICAL CANCER RESEARCH

Proteasome Inhibitors in Cancer Therapy: Lessons from the First Decade

(2008) R. Z. Orlowski et al.   CLINICAL CANCER RESEARCH

The stochastic nature of biochemical networks

(2008) Vahid Shahrezaei et al.   CURRENT OPINION IN BIOTECHNOLOGY

Lack of Nuclear Expression of Hairy and Enhancer of Split-1 (HES1) in Pancreatic Endocrine Tumors

(2008) T. Johansson et al.   HORMONE AND METABOLIC RESEARCH

Dissecting the dynamics of the Hes1 genetic oscillator

(2008) Hiroshi Momiji et al.   JOURNAL OF THEORETICAL BIOLOGY

Oscillations and bistability in the stochastic model of p53 regulation

(2008) Krzysztof Puszyński et al.   JOURNAL OF THEORETICAL BIOLOGY

Recurrent Initiation: A Mechanism for Triggering p53 Pulses in Response to DNA Damage

(2008) Eric Batchelor et al.   MOLECULAR CELL

Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors

(2008) M. J. I. Muller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of the Reversibility of Cellular Quiescence by the Transcriptional Repressor HES1

(2008) L. Sang et al.   SCIENCE