Article
Medicine, General & Internal
Po-Chang Chiang, Chia-Ying Lin, Ya-Chun Hsu, Li-Ting Huang, Ta-Jung Chung, Yi-Sheng Liu, Chao-Chun Chang
Summary: This study aimed to evaluate the safety and efficacy of early versus delayed drainage in patients with lung abscesses. The results showed that the length of hospital stay (LoS) was significantly shortened in the early drainage group, while there were no significant differences in 90-day mortality or perioperative complications between the two groups. Factors associated with higher mortality included a higher Charlson comorbidity index, secondary lung abscess, and liver cirrhosis. Positive sputum culture significantly increased the LoS.
FRONTIERS IN MEDICINE
(2023)
Article
Geriatrics & Gerontology
Andrea Kirfel, Jan Menzenbach, Vera Guttenthaler, Johanna Feggeler, Andreas Mayr, Mark Coburn, Maria Wittmann
Summary: The study aimed to compare the frequency of tested POD with the coded ICD diagnosis of POD and evaluate the impact of POD on ICU and hospital LOS. Results showed that approximately 50% of elderly patients undergoing cardiac surgery developed POD, which was significantly associated with prolonged LOS in ICU and hospital. Additionally, the underdiagnosis of POD in clinical routine was highlighted.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)
Article
Computer Science, Information Systems
Md. Mahbubur Rahman, Dipanjali Kundu, Sayma Alam Suha, Umme Raihan Siddiqi, Samrat Kumar Dey
Summary: This study proposes a federated machine learning-based model for predicting patients' length of stay (LOS) in hospitals. The model combines locally trained models from decentralized and heterogeneous hospital clients while maintaining data privacy. The findings show that the aggregated model with federated learning has more reliable predictive performance, and integrating more clients' parameters improves the model's performance.
JOURNAL OF KING SAUD UNIVERSITY-COMPUTER AND INFORMATION SCIENCES
(2022)
Article
Anesthesiology
Andrea Kirfel, Vera Guttenthaler, Andreas Mayr, Mark Coburn, Jan Menzenbach, Maria Wittmann
Summary: This study aimed to identify preoperative risk factors and the impact of postoperative delirium (POD) on length of stay in the ICU and hospital for older patients. The results showed that POD was an independent predictor for a prolonged length of stay in the ICU and hospital.
JOURNAL OF ANESTHESIA
(2022)
Review
Medicine, General & Internal
Apostolos Prionas, Charles Craddock, Vassilios Papalois
Summary: The study compared enhanced recovery after surgery (ERAS) with traditional perioperative care for renal transplant recipients. Results showed that ERAS decreased urological complications, shortened length of stay, and did not increase unplanned readmission rates.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Xinchen Ke, Wenrui Lin, Daishi Li, Shuang Zhao, Mingliang Chen, Yi Xiao, Xiang Chen, Minxue Shen, Juan Su
Summary: This study described the economic burden of melanoma patients in Hunan province, China, and investigated the factors influencing hospitalization spending and length of stay in patients undergoing melanoma surgery. The findings showed that melanoma imposes a heavy economic burden on patients, with middle-aged men with melanoma on the limbs experiencing the highest financial burden.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Jilu Lang, Yanan Shao, Jiehao Liao, Jia Chen, Xuewen Zhou, Rong Deng, Wei-Jian Wang, Xian Sun
Summary: The study investigated the relationship between nutritional status and length of hospital stay in Northern Chinese patients with lung adenocarcinoma (LUAD), finding that malnutrition was associated with a longer hospital stay. ICU patients had poorer nutritional status and longer stays. Risk for malnutrition based on PG-SGA, NRS 2002, and recent weight loss predicted longer hospital stays.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Oncology
Cecelia MacFarling Meure, Belinda Steer, Judi Porter
Summary: The relationship between nutritional intake and clinical outcomes in hospitalised adult oncology patients remains unclear. This study found no significant relationship between nutritional intake and clinical outcomes. However, patients at risk of malnutrition had longer length of stay.
Article
Surgery
Daan M. Voeten, Leonie R. van der Werf, Johanna W. van Sandick, Richard van Hillegersberg, Mark I. van Berge Henegouwen
Summary: This study aimed to analyze Dutch hospital performance in terms of length of hospital stay after esophageal cancer surgery and its association with 30-day readmission rates. Results showed no significant association between length of hospital stay and readmission rates.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Clinical Neurology
Ying Ma, Cuiying Li, Weiting Peng, Qiquan Wan
Summary: This study aimed to analyze the incidence, timing, risk factors, and prognosis of delirium after liver transplantation. The results showed a high incidence of delirium after liver transplantation, with early onset. High MELD score, pre-LT hepatic encephalopathy and infections, acute rejection, and reoperation were identified as independent risk factors for post-LT delirium. The intraoperative use of remimazolam or dexmedetomidine reduced the occurrence of delirium, and delirium had a negative impact on the length of ICU stay.
FRONTIERS IN NEUROLOGY
(2023)
Article
Health Care Sciences & Services
Andrew H. Hughes, David Jr Jr Horrocks, Curtis Leung, Melissa B. Richardson, Ann M. Sheehy, Charles F. S. Locke
Summary: The study found that outlier cases of length of stay are utilizing a growing share of hospital resources and beds, with both the mean outlier LOS and inpatient LOS excluding outliers increasing over the study period. Excluding these outliers from data reporting, based on the assumption of their rarity, may need to be reconsidered in order to implement targeted interventions that can effectively reduce length of stay, improve patient care, and maintain hospital capacity.
BMC HEALTH SERVICES RESEARCH
(2021)
Article
Medicine, General & Internal
Rodrigo B. Serafim, Felipe Dal-Pizzol, Vicente Souza-Dantas, Marcio Soares, Fernando A. Bozza, Pedro Povoa, Ronir Raggio Luiz, Jose R. Lapa E. Silva, Jorge I. F. Salluh
Summary: Despite recent advances in the field, the association between subsyndromal delirium (SSD) in the ICU and poor outcomes is not entirely clear. Our findings support the association of SSD with increased ICU length of stay (LOS), but not with ICU mortality. Monitoring the trajectory of SSD early at ICU admission can help to identify patients with increased risk of conversion from SSD to delirium or coma.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Dipankar Gupta, Neha Bansal, Byron C. Jaeger, Ryan C. Cantor, Devin Koehl, Allison K. Kimbro, Chesney D. Castleberry, Stephen G. Pophal, Alfred Asante-Korang, Kenneth Schowengerdt, James K. Kirklin, David L. Sutcliffe
Summary: This study examined LOS trends after pediatric heart transplantation and identified factors associated with prolonged LOS, particularly in patients with congenital heart disease.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2022)
Article
Medicine, General & Internal
Kuan-Hung Lin, Huey-Juan Lin, Poh-Shiow Yeh
Summary: This study aimed to explore the issue and method for improving the length of stay for patients with severe acute ischemic stroke. The results showed that patients with prolonged length-of-stay were younger, mostly male, more likely to receive reperfusion therapy, and less likely to have an early do-not-resuscitate order if signed. Although there was a lower rate of in-hospital mortality, there was a higher proportion with severe functional disability among the survivors.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Swapnil Patel, Abbas Alshami, Steven Douedi, Natasha Campbell, Mohammad Hossain, Arman Mushtaq, Dana Tarina, Brett Sealove, David Kountz, Kim Carpenter, Ellen Angelo, Vito Buccellato, Kenneth Sable, Elliot Frank, Arif Asif
Summary: JSUMC implemented a series of interventions, such as root cause analysis and obstacle interventions, which successfully reduced hospital length of stay and saved medical costs.
Article
Anesthesiology
Camilo Toro, Sonia Jain, Shelly Sun, Nancy Temkin, Jason Barber, Geoffrey M. Manley, Jordan M. Komisarow, Tetsu Ohnuma, Brandon Foreman, Frederick L. Korley, Michael L. James, Daniel S. Laskowitz, Monica S. Vavilala, Adrian P. Hernandez, Joseph P. J. Mathew, Amy J. Markowitz, Vijay Krishnamoorthy
Summary: This retrospective cohort study assessed the impact of brain injury biomarkers on the risk of circulatory shock in patients with moderate-severe traumatic brain injury. The study found an association between the levels of neuronal injury biomarkers and the development of circulatory shock. The results suggest that neuronal injury biomarkers may provide early identification of patients at risk for early circulatory shock following TBI.
JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Cynthia L. Green, Brian C. Gulack, Shaf Keshavjee, Lianne G. Singer, Kenneth McCurry, Marie M. Budev, Tammy L. Reece, Anne O. Lidor, Scott M. Palmer, R. Duane Davis
Summary: A multicenter retrospective study found limited benefits of fundoplication for preventing bronchiolitis obliterans syndrome and improving survival compared to reflux disease without surgery after lung transplantation. However, the study had limitations in terms of sample size, follow-up duration, and potential selection bias, highlighting the need for a randomized, prospective study.
ANNALS OF THORACIC SURGERY
(2023)
Review
Cardiac & Cardiovascular Systems
Maham F. Karatela, Marat Fudim, Joseph P. Mathew, Jonathan P. Piccini
Summary: Atrial fibrillation is influenced by both sympathetic and parasympathetic influences through cardiac autonomic innervation. Innovative therapies targeting the neurocardiac axis, such as catheter ablation or pharmacologic suppression of ganglionated plexi, renal sympathetic denervation, low-level vagal stimulation, and stellate ganglion blockade, have variable efficacy. Improving our understanding of atrial fibrillation and the cardiac nervous system will lead to further advancements in therapeutic neuromodulation for the benefit of patients with AF.
Article
Gastroenterology & Hepatology
Nancy Y. Yang, Alice Parish, Shai Posner, Rahul A. Shimpi, Richard K. Wood, R. Thomas Finn, Deborah A. Fisher, Matthew G. Hartwig, Jacob A. Klapper, John Reynolds, Donna Niedzwiecki, David A. Leiman
Summary: GERD is common in lung transplant recipients and is associated with poorer outcomes. In this study, impedance metrics were found to be more sensitive than pH-metry alone for detecting GERD. Abnormal acid exposure time (AET) was associated with worse survival, while low distal mean nocturnal baseline impedance (MNBI) was associated with decreased forced expiratory volume in 1 second (FEV1) at 3-year posttransplant. These findings suggest that pH-metry alone may be sufficient for guiding GERD management after lung transplant.
DISEASES OF THE ESOPHAGUS
(2023)
Article
Critical Care Medicine
Jordan Hatfield, Tetsu Ohnuma, Alexandria L. Soto, Jordan M. Komisarow, Monica S. Vavilala, Daniel T. Laskowitz, Michael L. James, Joseph P. Mathew, Adrian F. Hernandez, Benjamin A. Goldstein, Miriam Treggiari, Karthik Raghunathan, Vijay Krishnamoorthy
Summary: This retrospective cohort study aimed to describe the utilization patterns and clinical outcomes of ECMO in patients with TBI. The study found that ECMO utilization in mechanically ventilated patients with TBI is rare and varies significantly across hospitals. Patients who received ECMO had longer hospital and ICU stays as well as longer durations of mechanical ventilation compared to those who did not receive ECMO. The hospital mortality rate was also higher in patients exposed to ECMO.
JOURNAL OF INTENSIVE CARE MEDICINE
(2023)
Correction
Anesthesiology
Jeffrey N. Browndyke, Mary C. Wright, Rosa Yang, Ayesha Syed, John Park, Ashley Hall, Katherine Martucci, Michael J. Devinney, Leslie Shaw, Teresa Waligorska, Eugene W. Moretti, Heather E. Whitson, Harvey J. Cohen, Joseph P. Mathew, Miles Berger
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Letter
Anesthesiology
Christopher D. Lascola, Sarah F. Cotter, Rebecca Y. Klinger, Tiffany Bisanar, Mary Cooter Wright, Miles Berger, Gavin Martin, Mihai V. Podgoreanu, Mark F. Newman, Niccolo Terrando, Joseph P. Mathew
JOURNAL OF CLINICAL ANESTHESIA
(2023)
Article
Cardiac & Cardiovascular Systems
Jamie L. Todd, Jeremy M. Weber, Francine L. Kelly, Megan L. Neely, Andrew Nagler, Dylan Carmack, Courtney W. Frankel, David M. Brass, John A. Belperio, Marie M. Budev, Matthew G. Hartwig, Tereza Martinu, John M. Reynolds, Pali D. Shah, Lianne G. Singer, Laurie D. Snyder, S. Sam Weigt, Scott M. Palmer
Summary: This study found an association between reduced levels of club cell secretory protein (CCSP) in bronchoalveolar lavage fluid (BALF) and the development of chronic lung allograft dysfunction (CLAD) in lung transplant recipients. Decreased CCSP in early post-transplant BALF may indicate an increased risk of later CLAD.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2023)
Article
Virology
Lorenzo Zaffiri, Joshua E. Messinger, Erika J. Bush, Janet S. Staats, Prekshaben Patel, Scott M. Palmer, Kent J. Weinhold, Laurie D. Snyder, Micah A. Luftig
Summary: Reactivation of Epstein-Barr virus (EBV) is often seen in lung transplant recipients (LTRs), but the cellular immune responses to EBV in adult LTRs have not been fully described. In this study, we found significant changes in CD4/CD8 ratio, EBV-specific CD8(+)CD69(+) T cell responses, and NK cell phenotypic changes in adult LTRs with EBV-associated diseases. These findings provide valuable insights into the immune responses to EBV in adult LTRs and may contribute to improved management of EBV-related complications.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Medicine, Research & Experimental
Aaditya Khatri, Jamie L. . Todd, Fran L. . Kelly, Andrew Nagler, Zhicheng Ji, Vaibhav Jain, Simon G. Gregory, Kent J. Weinhold, Scott M. Palmer
Summary: Chronic lung allograft dysfunction (CLAD), characterized by decline in pulmonary function and bronchiolitis obliterans, lacks approved therapies. Single-cell RNA-Seq and spatial transcriptomic analysis identified the important role of JAK-STAT signaling in airway epithelial cells in CLAD. Activation of JAK-STAT signaling leads to upregulation of MHC-I in airway basal cells, resulting in cytotoxic T cell-mediated basal cell death. This study provides mechanistic insight and potential therapeutic strategy for CLAD.
Article
Cardiac & Cardiovascular Systems
Kamrouz Ghadimi, Jhaymie L. Cappiello, Mary Cooter Wright, Jerrold H. Levy, Benjamin S. Bryner, Adam D. Devore, Jacob N. Schroder, Chetan B. Patel, Sudarshan Rajagopal, Svati H. Shah, Carmelo A. Milano
Summary: In patients undergoing major cardiac surgery for advanced heart failure, inhaled pulmonary-selective vasodilator treatment using iEPO was associated with similar risks for RVF development and development of other postoperative secondary outcomes compared with treatment using iNO.
Article
Immunology
Jessica Goldsby, Kristi Beermann, Courtney Frankel, Alice Parish, Nicolas Stauffer, Amanda Schandert, Alaattin Erkanli, John M. Reynolds
Summary: This study compared lung transplant recipients who received preemptive immune globulin therapy to those who did not, and found that immune globulin therapy was associated with a lower development of donor-specific antibodies. However, there was no significant difference between the two groups in terms of post-transplant outcomes such as primary graft dysfunction, acute cellular rejection, antibody-mediated rejection, and chronic lung allograft dysfunction at 12 months. Larger randomized studies are needed to further investigate the association between immune globulin therapy and clinical outcomes.
TRANSPLANT IMMUNOLOGY
(2023)
Article
Critical Care Medicine
Omar Al-Qudsi, John M. Reynolds, John C. Haney, Ian J. Welsby
Summary: Hypoxia is a common issue in the ICU, occurring due to various pathological characteristics. The oxygen-hemoglobin dissociation curve explains the affinity between hemoglobin and PO2, as well as factors affecting oxygen uptake and release. Limited research exists on manipulating the hemoglobin-oxygen relationship. Voxelotor, a hemoglobin oxygen-affinity modulator approved by the FDA, was used to assist with chronic hypoxia and weaning off mechanical support in two non-sickle cell disease patients.
Meeting Abstract
Clinical Neurology
Heberto Suarez-Roca, Negmeldeen Mamoun, Lana L. Watkins, Andrey V. Bortsov, Joseph P. Mathew
Meeting Abstract
Clinical Neurology
Matthew Z. Yuan, Junli Zhao, Aidan McGinnis, Joseph P. Mathew, Fan Wang, Ru-Rong Ji
Article
Critical Care Medicine
Christina Boncyk, Kimberly Rengel, Joanna Stollings, Matt Marshall, Xiaoke Feng, Matthew Shotwell, Pratik P. Pandharipande, Christopher G. Hughes
Summary: This study describes the incidence and factors associated with recurrent delirium in the intensive care unit (ICU). The researchers found that over 10% of delirious ICU patients experienced recurrent symptoms, and factors such as age, duration of mechanical ventilation, and medication exposure were associated with recurrence.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Thomas C. Rollinson, Luke A. McDonald, Joleen Rose, Glenn Eastwood, Rahul Costa-Pinto, Lucy Modra, Akinori Maeda, Zoe Bacolas, James Anstey, Samantha Bates, Scott Bradley, Jodi Dumbrell, Craig French, Angaj Ghosh, Kimberley Haines, Tim Haydon, Carol L. Hodgson, Jennifer Holmes, Nina Leggett, Forbes McGain, Cara Moore, Kathleen Nelson, Jeffrey Presneill, Hannah Rotherham, Simone Said, Meredith Young, Peinan Zhao, Andrew Udy, Ary Serpa Neto, Anis Chaba, Rinaldo Bellomo
Summary: Neuromuscular blockers (NMBs) used during prone positioning in COVID-19 ARDS patients can improve oxygenation and have a sustained effect upon returning to supine position.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Kyung Hun Nam, Jason Phua, Bin Du, Shinichiro Ohshimo, Hwa Jung Kim, Chae-Man Lim, Sheila Nainan Myatra, Nik Azman Bin Nik Adib, Yaseen M. Arabi, Ming-Cheng Chan, Mohammad Omar Faruq, Ike Sri Redjeki, Do Ngoc Son, Khalid Mahmood Khan Nafees, Dilshan Priyankara, Boonsong Patjanasoontorn, Jose Emmanuel Palo, Aidos Konkayev, Gentle Sunder Shrestha, Younsuck Koh
Summary: This study investigated the current practices of mechanical ventilation in Asian intensive care units. The results showed that low tidal volume ventilation and sufficient PEEP were underused in patients with ARDS, while intermediate tidal volumes were commonly used in patients without ARDS. Country income, age, and severity of illness were associated with mortality.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Rudolf Likar, Ilia Aroyo, Katrin Bangert, Bjorn Degen, Rainer Dziewas, Oliver Galvan, Michaela Trapl Grundschober, Markus Kostenberger, Paul Muhle, Joerg C. Schefold, Patrick Zuercher
Summary: This article presents expert opinions on the diagnosis and management of dysphagia in ICU patients. The panel suggests adopting clinical algorithms to promote standardized and high-quality care, and proposes two clinical management algorithms to improve early detection and effective treatment of dysphagia in ICU patients.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Pawel Pasieka, Anna Surowka, Jakub Fronczek, Evan Skwara, Miroslaw Czuczwar, Michal Borys, Pawel Krawczyk, Miroslaw Zietkiewicz, Lukasz R. Nowak, Maciej Zukowski, Katarzyna Kotfis, Katarzyna Cwyl, Jacek Skowronek, Joanna Solek-Pastuszka, Jowita Biernawska, Pawel Grudzien, Pawel Nasilowski, Natalia Popek, Waldemar Cyrankiewicz, Katarzyna Sierakowska, Wojciech Mudyna, Szymon Bialka, Dorota Studzinska, Szymon Bernas, Mariusz Piechota, Waldemar Machala, Lukasz Sadowski, Jan Stefaniak, Radoslaw Owczuk, Malgorzata Szymkowiak, Ryszard Gawda, Natalia Kozera, Barbara Adamik, Waldemar Gozdzik, Agnieszka Wieczorek, Jaroslaw Janc, Anna Kluzik, Janusz Trzebicki, Pawel Zatorski, Wojciech Gola, Hubert Hymczak, Lukasz J. Krzych, Szymon Czajka, Urszula Kosciuczuk, Bartosz Kudlinski, Hans Flaatten, Wojciech Szczeklik
Summary: The study aims to evaluate whether there is an increased propensity to limit life-sustaining treatment (LST) among elderly patients in Poland from 2018-2019 compared to 2016-2017. The results show that clinicians in Poland have become more proactive in limiting LST in critically ill patients aged 80 and above during the studied period, although the prevalence of LST limitations in Poland remains low.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Jihad Mallat, Malcolm Lemyze, Marc-Olivier Fischer
Summary: In mechanically ventilated patients with acute circulatory failure, changes in PVI induced by PLR accurately predict fluid responsiveness.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Jingyuan Xu, Yanjie Zhang, Jie Jiang, Yi Yang, Fengmei Guo
Summary: This meta-analysis examined the effect of milrinone on prognosis in adult critically ill patients and found a significant decrease in the incidence of ventricular arrhythmia in patients with cardiac surgery. However, there was no significant reduction in all-cause mortality or the incidence of myocardial infarction. More research is needed to determine the reliable and conclusive evidence for the effects of milrinone.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Zhi-Tao Li, Da-Bing Huang, Jian-Feng Zhao, Hui Li, Shui-Qiao Fu, Wei Wang
Summary: Venous congestion is associated with AKI after cardiac surgery, but not necessarily with CRRT. Among the markers tested, IRVF exhibits the strongest correlation with AKI.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Sarah E. Nelson, Spyridoula Tsetsou, John Liang
Summary: This article discusses a range of issues associated with tracking CLABSI and CAUTI metrics, including lack of evidence, moral distress, and definition problems. It recommends forming a task force consisting of key stakeholders to improve the use of these metrics.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Ross Prager, Eric Walser, Kaan Y. Balta, Anton Nikouline, William R. Leeper, Kelly Vogt, Neil Parry, Robert Arntfield
Summary: Resuscitative TEE has been shown to be a valuable diagnostic tool in trauma care, with the potential to impact treatment strategies and diagnostic approaches for patients in the trauma bay.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Jaeyun Sung, Sanu S. Rajendraprasad, Kemuel L. Philbrick, Brent A. Bauer, Ognjen Gajic, Aditya Shah, Krzysztof Laudanski, Johan S. Bakken, Joseph Skalski, Lioudmila V. Karnatovskaia
Summary: With a large number of cells and genes, the human gut microbiome is crucial for health and disease. Modern living disrupts the balance between the host and its microbiome, leading to adverse impacts on critical illness and patient outcomes. Restoring the gut microbiome shows promise for preventing and treating critical illnesses.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Claire Chaignat, Laurent Lagrost, Karena Moretto, Jean-Paul Pais de Barros, Hadrien Winiszewski, Jacques Grober, Philippe Saas, Gael Piton
Summary: The aim of this study was to investigate the correlation between plasma citrulline levels and plasma lipopolysaccharide (LPS) concentration, as well as the impact of sepsis on gut function in critically ill patients. The results showed no correlation between plasma citrulline concentration and plasma LPS concentration or activity. However, septic patients had significantly lower plasma citrulline levels. Additionally, abdominal sepsis was associated with higher plasma LPS activity compared to extra-abdominal sepsis.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Pyoung Jik Lee, Thomas Hampton
Summary: This study found that smartphone applications with low-cost external microphones can reliably measure average noise levels in both laboratory and field settings, but show significant differences compared to professional equipment when measuring maximum noise levels.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Greg Roberts, James S. Krinsley, Jean-Charles Preiser, Stephen Quinn, Peter R. Rule, Michael Brownlee, Guillermo E. Umpierrez, Irl B. Hirsch
Summary: Relative hypoglycemia was commonly seen in patients with HbA1c ≥ 8% and was independently associated with mortality. Absolute hypoglycemia was associated with mortality regardless of HbA1c.
JOURNAL OF CRITICAL CARE
(2024)
Article
Critical Care Medicine
Katsura Hayakawa, Shigehiko Uchino, Hideki Endo, Kazuki Hasegawa, Kazuya Kiyota
Summary: This study assessed the performance of the APACHE III and JROD models under different conditions of missing variables and found that a higher number of missing physiological variables led to underestimated predicted mortality rates and higher standardized mortality ratios.
JOURNAL OF CRITICAL CARE
(2024)
