Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 153, Issue 6, Pages 867-869Publisher
SPRINGER
DOI: 10.1007/s10517-012-1846-x
Keywords
HSPA1A; HSPBP1; PGLYRP1; exercise
Categories
Funding
- Federal Target Program Research and Development of the Priority Trends of Scientific and Technological Complex of Russia [16.512.11.2211]
- Federal Target Program Scientific and Pedagogical Staff of Innovation Russia [14.740.11.0117]
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The effects of 30-min medium-intensity exercise on the expression of genes encoding heat shock protein 70 (HSPA1A) and its cochaperones HSP-70-binding protein 1 (HSPBP1) and Tag7 (PGLYRP1) in human leukocytes were studied. Transcription activities of HSPA1A and PGLYRP1 genes increased immediately after medium-intensity exercise, while activity of HSPBP1 gene remained unchanged. During recovery after exercise, the expression of HSPA1A gene virtually did not change, while the expression of PGLYRP1 gene continued to increase and after 90 min more than 2-fold surpassed the basal level.
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