Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 146, Issue 1, Pages 153-157Publisher
SPRINGER
DOI: 10.1007/s10517-008-0225-0
Keywords
IIIa-degree burn wound; biological dressing; allofibroblasts; collagen-1; PDGF-BB
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Clinical and morphological comparison of wound healing after transplantation of living cultured allofibroblast on days 1-2 after the injury, collagen-1-based dressing with PDGF-BB, and traditional dressing with levomecol ointment showed that bioactive dressing accelerated wound epithelialization (5-7 days vs. 20-22 days with gauze dressing); the incidence of suppurative complications decreased, no crust formed, and epithelialization was not associated with the formation of a hypertrophic cicatrix. Biological dressing based on living cultured allofibroblasts and collagen-1 with PDGF-BB exhibited equal stimulatory effects on burn wound healing.
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