Article
Surgery
Bor-Uei Shyr, Bor-Shiuan Shyr, Shih-Chin Chen, Yi-Ming Shyr, Shin-E Wang
Summary: While RPD showed better outcomes in terms of surgical time, blood loss, complications, and postoperative delayed gastric emptying, it had similar oncological outcomes in terms of lymph node yield and 5-year survival rate compared to OPD. The study suggests that RPD is technically feasible and oncologically justifiable for pancreatic adenocarcinoma patients.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Review
Surgery
Alberto Aiolfi, Francesca Lombardo, Gianluca Bonitta, Piergiorgio Danelli, Davide Bona
Summary: A meta-analysis compared the short-term surgical and oncologic outcomes of Open Pancreaticoduodenectomy (OpenPD), Laparoscopic Pancreaticoduodenectomy (LapPD), and Robotic Pancreaticoduodenectomy (RobPD). LapPD and RobPD showed similar outcomes to OpenPD in terms of mortality, postoperative pancreatic fistula, and severe complications, but had advantages in reduced hospital stay, blood loss, and overall complications. Minimally invasive techniques may improve outcomes for periampullary and pancreatic head neoplasms.
UPDATES IN SURGERY
(2021)
Article
Surgery
Ji Su Kim, Munseok Choi, Sung Hyun Kim, Sung Hoon Choi, Chang Moo Kang
Summary: This study investigated the safety and feasibility of laparoscopic pancreaticoduodenectomy (LPD) in octogenarians. The results showed that LPD is a good alternative for octogenarians with periampullary tumors requiring pancreaticoduodenectomy, with similar outcomes to open PD.
ASIAN JOURNAL OF SURGERY
(2022)
Article
Gastroenterology & Hepatology
Hyeyeon Kim, Seo Young Park, Yejong Park, Jaewoo Kwon, Woohyung Lee, Ki Byung Song, Dae Wook Hwang, Song Cheol Kim, Jae Hoon Lee
Summary: This study retrospectively analyzed the medical records of 70 cases of robotic pancreaticoduodenectomy (R-PD) and compared the results with 269 cases of open pancreaticoduodenectomy (O-PD). The results showed that the surgical outcomes of R-PD improved over time, but there were differences compared to O-PD in certain aspects.
JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
(2022)
Article
Oncology
Marcel Autran Machado, Bruno Mattos, Murillo Macedo Lobo Filho, Fabio Makdissi
Summary: Robotic total mesopancreas excision and triangle operation are feasible and safe for selected patients, with indications including high risk for R1 resection and locally advanced disease. The video presentation may assist oncological surgeons in performing these techniques effectively.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Review
Oncology
Lanwei Ouyang, Jia Zhang, Qingbo Feng, Zhiguang Zhang, Hexing Ma, Guodong Zhang
Summary: Overall, this meta-analysis included 9 retrospective studies with a total of 3,732 patients, of which 1,149 (30.79%) underwent robotic pancreaticoduodenectomy (RPD) and 2,583 (69.21%) underwent LPD. The findings suggested that RPD had advantages over LPD in terms of less blood loss, lower conversion rate, less vascular resection, and more retrieved lymph nodes.
FRONTIERS IN ONCOLOGY
(2022)
Article
Surgery
Thiagarajan Meyyappan, Greg C. Wilson, Herbert J. Zeh, Melissa E. Hogg, Kenneth K. Lee, Amer H. Zureikat, Alessandro Paniccia
Summary: The aim of this study was to compare the effect of major complications (MCs) on overall survival (OS) and disease-free survival (DFS) after robotic pancreaticoduodenectomy (RPD) and open pancreaticoduodenectomy (OPD). It was found that MCs were associated with worse patient outcomes after OPD but not after RPD. Robotic approach mitigates and possibly abrogates the negative effects of MCs on patient outcomes after pancreaticoduodenectomy for malignancy and is associated with improved adjuvant chemotherapy completion rates.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Yosuke Inoue, Takafumi Sato, Tomotaka Kato, Atsushi Oba, Yoshihiro Ono, Yoshihiro Mise, Hiromichi Ito, Yu Takahashi
Summary: This study details the technical tips for performing clipless modified Blumgart anastomosis (MBA) in a robotic environment. The results show that the robotic approach has acceptable short-term outcomes, with longer operation time but lower blood loss and shorter hospital stay compared to open surgery.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Medicine, General & Internal
Lea Timmermann, Matthias Biebl, Moritz Schmelzle, Marcus Bahra, Thomas Malinka, Johann Pratschke
Summary: Robotic assisted minimally invasive pancreatic surgery was safe and feasible in this study, with decreasing procedure times and overall complication rates. However, reintervention and reoperation rates remained relatively high, indicating further improvements may be needed in certain aspects of the procedures.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Surgery
Munseok Choi, Seoung Yoon Rho, Sung Hyun Kim, Ho Kyoung Hwang, Woo Jung Lee, Chang Moo Kang
Summary: LPD and RALPD are safe and effective for MIPD and can complement each other to achieve the goal of minimally invasive surgery.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Cho-Han Chiang, Cho-Hsien Chiang, Teng-Chieh Cheng, Cho-Hung Chiang, Ching-Lung Hsieh, Jhong- Peng, Cheng-Ming Peng
Summary: This study compared the safety and efficacy of reduced-port robotic pancreaticoduodenectomy (RPD) with open pancreaticoduodenectomy (OPD) in pancreatic cancer surgery. The results showed that reduced-port RPD was associated with less blood loss and longer operative time compared to OPD. Patients who underwent reduced-port RPD had a higher 1-year survival rate compared to those who underwent OPD.
Review
Surgery
Yibo Fu, Jiangdong Qiu, Yiqi Yu, Danning Wu, Taiping Zhang
Summary: A comparison between robotic pancreaticoduodenectomy (RPD) and open pancreaticoduodenectomy (OPD) showed that RPD is safer with better perioperative outcomes and lower blood loss. However, in terms of oncological outcomes, RPD does not have an advantage over OPD, and it is also more expensive.
FRONTIERS IN SURGERY
(2022)
Article
Surgery
Emanuele F. Kauffmann, Niccolo Napoli, Michael Ginesini, Cesare Gianfaldoni, Fabio Asta, Alice Salamone, Gabriella Amorese, Fabio Vistoli, Ugo Boggi
Summary: This study demonstrates the feasibility of cold triangle robotic pancreaticoduodenectomy (C-Tr-RPD) for pancreatic cancer. The surgical procedure involves cold dissection and has been successfully performed in 127 cases. Although there were postoperative complications, C-Tr-RPD improves staging of PDAC compared to traditional surgery.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Hussein H. Khachfe, Ibrahim Nassour, Abdulrahman Y. Hammad, Jacob C. Hodges, Samer AlMasri, Hao Liu, Anissa deSilva, Jasmine Kraftician, Kenneth K. Lee, Henry A. Pitt, Amer H. Zureikat, Alessandro Paniccia
Summary: This study compared the rate of postoperative 30-day complications between laparoscopic pancreaticoduodenectomy (LPD) and robotic pancreaticoduodenectomy (RPD). The results showed that during 2018-2019, RPD had lower overall complications, serious complications, and higher optimal outcome compared with LPD.
Review
Surgery
Artemis Mantzavinou, Mallikarjuna Uppara, Jeremy Chan, Bijendra Patel
Summary: Robotic pancreaticoduodenectomy (PD) is a safe and effective alternative to open PD, with a higher therapeutic index and comparable safety outcomes. Randomized controlled trials are needed to further establish the efficacy of robotic PD.
INTERNATIONAL JOURNAL OF SURGERY
(2022)
Article
Immunology
Ugo Boggi, Walter Baronti, Gabriella Amorese, Silvia Pilotti, Margherita Occhipinti, Vittorio Perrone, Lorella Marselli, Massimiliano Barsotti, Daniela Campani, Elena Gianetti, Andrea Cacciato Insilla, Emanuele Bosi, Emanuele Kaufmann, Chiara Terrenzio, Fabio Vistoli, Piero Marchetti
Summary: This study investigates the long-term efficacy and safety of pancreas transplant alone (PTA) in type 1 diabetes (T1D) patients. The findings demonstrate that PTA can improve patient survival, graft function, and native kidney function in carefully selected T1D patients.
Review
Oncology
Angiolo Gadducci, Clara Ugolini, Stefania Cosio, Fabio Vistoli, Emanuele Federico Kaufmann, U. G. O. Boggi
Summary: This case report highlights the importance of long-term follow-up for gynecological PEComas, as recurrence may occur even after surgical intervention.
ANTICANCER RESEARCH
(2021)
Review
Transplantation
Fabio Vistoli, Emanuele F. Kauffmann, Ugo Boggi
Summary: Recent major events in pancreas transplantation (PT) include the COVID-19 pandemic and the first world consensus conference on PT. Studies following the conference have shown that PT alone is safe and effective, simultaneous pancreas and kidney (SPK) outcomes are excellent despite certain risk factors, and the use of HCV positive donors can lead to positive outcomes. The results of using sirolimus as primary immunosuppressant and costimulation blockade in SPK have not shown improvement.
CURRENT OPINION IN ORGAN TRANSPLANTATION
(2021)
Article
Robotics
Veronica Iacovacci, Izadyar Tamadon, Emanuele Federico Kauffmann, Stefano Pane, Virginia Simoni, Leonardo Marziale, Michele Aragona, Luigi Cobuccio, Massimo Chiarugi, Paolo Dario, Stefano Del Prato, Leonardo Ricotti, Fabio Vistoli, Arianna Menciassi
Summary: The study introduces a fully implantable robotic device, PILLSID, which can be refilled through ingestible magnetic pills to achieve precise intraperitoneal drug delivery, safely regulating blood glucose levels in diabetic patients and addressing critical issues related to reservoir refilling and powering.
Article
Gastroenterology & Hepatology
Niccolo Napoli, Emanuele F. Kauffmann, Rosilde Caputo, Michael Ginesini, Fabio Asta, Cesare Gianfaldoni, Gabriella Amorese, Fabio Vistoli, Ugo Boggi
Summary: This study describes the technique and results of double-layer continuous suture hepaticojejunostomy (HJ) following pancreatoduodenectomy (PD) and total pancreatectomy (TP). The study found that this technique is associated with low rates of biliary leaks (BL) and an acceptable incidence of late complications.
Article
Surgery
Emanuele F. Kauffmann, Niccolo Napoli, Michael Ginesini, Cesare Gianfaldoni, Fabio Asta, Alice Salamone, Gabriella Amorese, Fabio Vistoli, Ugo Boggi
Summary: This study demonstrates the feasibility of cold triangle robotic pancreaticoduodenectomy (C-Tr-RPD) for pancreatic cancer. The surgical procedure involves cold dissection and has been successfully performed in 127 cases. Although there were postoperative complications, C-Tr-RPD improves staging of PDAC compared to traditional surgery.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Emanuele F. Kauffmann, Niccolo Napoli, Michael Ginesini, Cesare Gianfaldoni, Fabio Asta, Alice Salamone, Allegra Ripolli, Armando Di Dato, Fabio Vistoli, Gabriella Amorese, Ugo Boggi
Summary: In this study, we provided a detailed description of the technical challenges associated with robotic pancreatoduodenectomy with vein resection (RPD-VR) and shared tips and tricks for a successful operation. Our results showed that RPD-VR can be effectively performed using different vascular techniques for different types of vein resection. We strongly recommend that RPD-VR should be performed by experienced surgeons at high volume centers.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Niccolo Napoli, Concetta Cacace, Emanuele F. Kauffmann, Leia Jones, Michael Ginesini, Cesare Gianfaldoni, Alice Salamone, Fabio Asta, Allegra Ripolli, Armando Di Dato, Olivier R. Busch, Marie L. Cappelle, Ying Jui Chao, Roeland F. de Wilde, Thilo Hackert, Jin-Young Jang, Bas Groot Koerkamp, Wooil Kwon, Daan Lips, Misha D. P. Luyer, Felix Nickel, Olivier Saint-Marc, Yan-Shen Shan, Baiyong Shen, Fabio Vistoli, Marc G. Besselink, Mohammad Abu Hilal, Ugo Boggi
Summary: This study developed a difficulty score for robotic pancreatoduodenectomy, which can predict severe postoperative complications. The score was validated in multiple cohorts and showed good performance in predicting complications. The score also predicted other surgical outcomes and is available online.
Article
Surgery
Emanuele Federico Kauffmann, Niccolo Napoli, Armando Di Dato, Alice Salamone, Michael Ginesini, Cesare Gianfaldoni, Virginia Viti, Gabriella Amorese, Carla Cappelli, Fabio Vistoli, Ugo Boggi
Summary: This retrospective study demonstrates the importance of preoperative planning in minimally invasive radical antegrade modular pancreatosplenectomy (MI-RAMPS) by measuring the distances between the tumor and the spleno-mesenteric confluence (d-SMC) or the gastroduodenal artery (d-GDA) using computed tomography.
UPDATES IN SURGERY
(2023)
Article
Surgery
Niccolo Napoli, Emanuele F. Kauffmann, Michael Ginesini, Lucrezia Lami, Carlo Lombardo, Fabio Vistoli, Daniela Campani, Ugo Boggi
Summary: This study aimed to define the prognostic value of Ca 125 in resected PDAC of the head of the pancreas. Data from PDAC patients who underwent pancreatic resection between 2010 and 2018 were analyzed, and it was found that Ca 125 can predict overall survival and correlates with tumor stage, lymph node status, and tumor grade in borderline resectable and locally advanced PDAC.
UPDATES IN SURGERY
(2023)
Article
Surgery
Joana Ferrer-Fabrega, Benoit Mesnard, Franka Messner, Jason B. Doppenberg, Cinthia Drachenberg, Marten A. Engelse, Paul R. V. Johnson, Henri G. D. Leuvenink, Gabriel C. Oniscu, Vassilios Papalois, Rutger J. Ploeg, Trevor W. Reichman, William E. Scott III, Fabio Vistoli, Thierry Berney, Daniel Jacobs-Tulleneers-Thevissen, Nicos Kessaris, Annemarie Weissenbacher, Ann Etohan Ogbemudia, Steve White, Julien Branchereau, ESOT Guidelines Taskforce
Summary: The use of Machine Perfusion (MP) in preserving and evaluating pancreas for beta-cell replacement has shown promising results. However, further refinement is needed in terms of perfusion protocols and organ viability assessment criteria. The European Society for Organ Transplantation (ESOT) has formed a working group to review literature and develop evidence-based guidelines for using MP in improving donor pancreas quality and quantity for transplantation.
TRANSPLANT INTERNATIONAL
(2023)
Article
Surgery
Niccolo Napoli, Emanuele F. Kauffmann, Michael Ginesini, Cesare Gianfaldoni, Pamela Fiaschetti, Ilaria Lombardi, Massimo Cardillo, Fabio Vistoli, Ugo Boggi
Summary: This study investigated living donor kidney transplantation (LDKTx) activities in Italy and the safety measures implemented in living donor nephrectomy (LDN). The results showed no postoperative donor deaths and a 10-year donor survival rate of 93.38%. There were cases of renal disease in some donors, but the proportion was relatively low. The survey also revealed the presence of safety measures in some transplant centers, but improvements are needed.
UPDATES IN SURGERY
(2023)
Article
Surgery
Ugo Boggi, Niccolo Napoli, Emanuele F. Kauffmann, Sara Iacopi, Michael Ginesini, Cesare Gianfaldoni, Daniela Campani, Gabriella Amorese, Fabio Vistoli
BRITISH JOURNAL OF SURGERY
(2023)
Article
Engineering, Biomedical
Angela Mazzeo, Veronica Iacovacci, Laura Riacci, Diego Trucco, Gina Lisignoli, Fabio Vistoli, Leonardo Ricotti
Summary: This paper describes the design of a chip modeling the proximal renal tubule, including a 3D convoluted geometry and a perfusion system. Various formulations were investigated, with optimal results found using a matrix composed mainly of Matrigel and Collagen I.
IEEE TRANSACTIONS ON MEDICAL ROBOTICS AND BIONICS
(2021)
Article
Surgery
Emanuele Federico Kauffmann, Niccolo Napoli, Francesca Menonna, Concetta Cacace, Valerio Genovese, Fabio Vistoli, Ugo Boggi
Summary: A 28-year-old female patient was diagnosed with mucinous cystadenoma and underwent robot-assisted distal pancreatectomy, which was completed safely with a smooth post-operative course.
ANNALS OF LAPAROSCOPIC AND ENDOSCOPIC SURGERY
(2021)