Article
Dermatology
Panfeng Wang, Dandan Wang, Lingqiao Zhang
Summary: This study conducted a systematic evaluation to assess the efficacy of chlorhexidine and povidone-iodine as primary components in preventing surgical site infection (SSI). The meta-analysis results indicated that chlorhexidine was more effective than povidone-iodine in reducing the incidence of surgical site wound infections, superficial SSIs, and deep SSIs.
INTERNATIONAL WOUND JOURNAL
(2023)
Review
Nursing
Li Li, Yu Wang, Shouyan Wang
Summary: This study conducted a systematic review and meta-analysis to evaluate the efficacy of chlorhexidine and povidone-iodine in preventing postoperative surgical site infections (SSI) and relevant bacterial data. The results indicated that chlorhexidine was more effective than povidone-iodine in preventing SSI, and the two disinfectants had different effects on bacterial colonization depending on the type of incision.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2022)
Review
Surgery
Tatsuki Hasegawa, Sho Tashiro, Takayuki Mihara, Junya Kon, Kazuki Sakurai, Yoko Tanaka, Takumi Morita, Yuki Enoki, Kazuaki Taguchi, Kazuaki Matsumoto, Kazuhiko Nakajima, Yoshio Takesue
Summary: This study demonstrates the effectiveness of alcohol-based CHG solution with a 0.5 per cent or higher concentration in surgical skin preparation to prevent SSI, providing valuable insights for healthcare practices.
Review
Dermatology
Dunyao Bai, Fan Zhou, Liuting Wu
Summary: Surgical site infections (SSIs) have a significant impact on patient health and healthcare costs. This meta-analysis examines the effectiveness of antiseptics, chlorhexidine and povidone-iodine, in reducing SSIs and concludes that chlorhexidine is more effective than povidone-iodine.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Surgery
Ryo Maemoto, Hiroshi Noda, Kosuke Ichida, Yasuyuki Miyakura, Nao Kakizawa, Erika Machida, Hidetoshi Aizawa, Takaharu Kato, Masahiro Iseki, Taro Fukui, Yuta Muto, Shota Fukai, Shingo Tsujinaka, Yuuri Hatsuzawa, Fumiaki Watanabe, Masakazu Nagamori, Jun Takahashi, Yasuaki Kimura, Shimpei Maeda, Noriya Takayama, Ryotaro Sakio, Rei Takahashi, Tsutomu Takenami, Natsumi Matsuzawa, Makiko Mieno, Toshiki Rikiyama
Summary: This trial evaluated the superiority of intraoperative wound irrigation with povidone-iodine compared with saline for reducing surgical site infection. The results showed that the irrigation with povidone-iodine did not significantly reduce the incidence of incisional SSI, suggesting a need for reconsideration of the current recommendation.
Article
Dermatology
Chunmei Fu, Linghong Meng, Miguo Ma, Na Li, Jingcen Zhang
Summary: The meta-analysis found that both antibiotic irrigation and aqueous povidone-iodine irrigation significantly reduced the risk of surgical site infections compared to saline irrigation or no irrigation. Further research is needed to validate these findings.
INTERNATIONAL WOUND JOURNAL
(2022)
Article
Medicine, General & Internal
Gerard P. Slobogean, Sheila Sprague, Jeffrey L. Wells, Lehana Thabane, C. Daniel Mullins, Anthony D. Harris, Amber Wood Msn, Roman M. Natoli, Todd O. McKinley, William Obremskey, Phillip M. Mitchell, Jennifer E. Hagen, Marissa Pazik, Stephen J. Warner, Joshua L. Gary, Herman Johal, Jodi L. Gallant, Kyle J. Jeray, Stephanie L. Tanner, Justin Fowler, Sarah N. Pierrie, Robert O'Toole, Andrea L. Howe, Michael J. Prayson, Jennifer Jerele, Christina L. Boulton, Jason Lowe, Niloofar Dehghan, Michael D. McKee, Saam Morshed, Meir T. Marmor, Ernesto Guerra-Farfan, Yaiza Garcia-Sanchez, Francesc Marcano-Fernandez, Laia Martinez-Carreres, Nathan N. O'Hara, Shannon Dodds, David Pogorzelski, Sofia Bzovsky, Diane Heels-Ansdell, Olivia Paige Szasz, Gregory J. Della Rocca, Robert D. Zura, Lucas S. Marchand, Joan N. Hebden, Joseph T. Patterson, Christopher Lee, Lyndsay M. O'Hara, Debra Marvel, Jana E. Palmer, I. Leah Gitajn, Jean-Claude G. D'alleyrand, Jessica C. Rivera, Franca Mossuto, Manjari Joshi, Jeff Friedrich, Gordon Guyatt, P. J. Devereaux, Mohit Bhandari
Summary: This study compared the effect of aqueous 10% povidone-iodine and aqueous 4% chlorhexidine gluconate on the risk of surgical site infection in patients with open fractures requiring surgery. The results showed no significant difference between the two groups. Either aqueous 10% povidone-iodine or aqueous 4% chlorhexidine gluconate can be selected for skin antisepsis in patients with open fractures based on availability, contraindications, or cost.
Article
Medicine, General & Internal
Summary: A trial conducted in low-income and middle-income countries did not demonstrate benefits of 2% alcoholic chlorhexidine skin preparation compared with povidone-iodine, or triclosan-coated sutures compared with non-coated sutures, in preventing surgical site infections in cleancontaminated or contaminated or dirty surgical wounds. Both interventions are more costly than alternatives, and these results do not endorse routine use.
Article
Gastroenterology & Hepatology
Fiona S. Reid, Bree Stephensen, Rosemary Carroll, Natalie Lott, John R. Attia, Stephen R. Smith
Summary: This study compared the efficacy of chlorhexidine in alcohol, povidone-iodine in alcohol, and povidone-iodine in aqueous solution for preventing surgical site infection in colorectal surgery. The results showed no difference in surgical site infection, complications, or length of stay among the three skin preparation methods.
DISEASES OF THE COLON & RECTUM
(2022)
Article
Public, Environmental & Occupational Health
L-Y. Zhao, W-H. Zhang, K. Liu, X-L. Chen, K. Yang, X-Z. Chen, J-K Hu
Summary: This study compared the efficacy of wound irrigation with normal saline (NS) and povidone-iodine (PVI) for the prevention of surgical site infection (SSI) after gastrectomy and found that both solutions had similar efficacy. High body mass index (BMI) and postoperative complications were identified as independent risk factors for SSI.
JOURNAL OF HOSPITAL INFECTION
(2023)
Review
Oncology
Thais Almeida Dias, Daiane Rubinato Fernandes, Bruna Nogueira dos Santos, Paula Elaine Diniz dos Reis, Amanda Salles Margatho, Renata Cristina de Campos Pereira Silveira
Summary: This systematic review aimed to identify the most effective dressing for preventing surgical site infection (SSI) in adult cancer patients undergoing elective surgeries. The results showed that silver dressings and negative pressure wound therapy did not reduce the risk of SSI.
SUPPORTIVE CARE IN CANCER
(2023)
Review
Infectious Diseases
Hasti Jalalzadeh, Hannah Groenen, Dennis R. Buis, Yasmine E. M. Dreissen, Jon H. M. Goosen, Frank F. A. Ijpma, Maarten J. van der Laan, Roald R. Schaad, Patrique Segers, Wil C. van der Zwet, Mitchel Griekspoor, Wouter J. Harmsen, Niels Wolfhagen, Marja A. Boermeester
Summary: This study compared the efficacy of different skin preparation solutions for preventing SSIs in adult patients. Results showed that 2.0-2.5% chlorhexidine in alcohol and 1.5% olanexidine were most effective in preventing SSIs. No specific concentration of chlorhexidine in alcohol was recommended for clean surgery.
Article
Clinical Neurology
Cindy Mallet, Victor Meissburger, Marion Caseris, Adele Happiette, Jason Chinnappa, Stephane Bonacorsi, Anne-Laure Simon, Brice Ilharreborde
Summary: This study investigated the impact of using intrawound PVP-I irrigation and local vancomycin powder on the incidence of early surgical site infection (SSI) in adolescent idiopathic scoliosis (AIS) surgery. The results showed that the use of intrawound PVP-I irrigation and vancomycin powder was associated with a significant reduction in early SSI and a lower rate of surgical revision.
EUROPEAN SPINE JOURNAL
(2022)
Review
Ophthalmology
Julio Gonzalez Martin-Moro, Jesus Zarallo-Gallardo, Elena Guzman-Almagro, Cristina Anton Rodriguez
Summary: There is great uncertainty about the usefulness of topical povidone iodine (PI) in the treatment of adenoviral conjunctivitis (AC). PI-DXM may have a small effect on AC duration. Future studies should standardize the reporting of results and include etiological confirmation and aspects relevant to patient quality of life.
CONTACT LENS & ANTERIOR EYE
(2023)
Review
Medicine, General & Internal
Marwan El Mobadder, Samir Nammour, Zuzanna Grzech-Lesniak, Kinga Grzech-Lesniak
Summary: This systematic review evaluated the efficacy of combining sodium hypochlorite or povidone-iodine as disinfection solutions with non-surgical treatment of periodontitis. The results showed that povidone-iodine did not significantly improve clinical outcomes, while sodium hypochlorite showed significant improvement in probing pocket depth and clinical attachment level. However, further studies are needed to confirm these findings.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Genetics & Heredity
Emilie Tisserant, Antonio Vitobello, Davide Callegarin, Simon Verdez, Ange-Line Bruel, Ludwig Serge Aho Glele, Arthur Sorlin, Eleonore Viora-Dupont, Marina Konyukh, Nathalie Marle, Sophie Nambot, Sebastien Moutton, Caroline Racine, Aurore Garde, Julian Delanne, Frederic Tran-Mau-Them, Christophe Philippe, Paul Kuentz, Marlene Poulleau, Muriel Payet, Charlotte Poe, Christel Thauvin-Robinet, Laurence Faivre, Anne-Laure Mosca-Boidron, Julien Thevenon, Yannis Duffourd, Patrick Callier
Summary: Copy Number Variants (CNVs) account for a significant portion of patients affected by Developmental Disorder (DD)/Intellectual Disability (ID). Traditional array comparative genomic hybridization (array-CGH) has limitations in detecting small CNVs, while Whole Exome sequencing (WES) offers higher resolution. In this study, XHMM software was used to detect CNVs from WES data and identified pathogenic CNVs in a cohort of unsolved DD/DI patients.
ANNALS OF HUMAN GENETICS
(2022)
Review
Public, Environmental & Occupational Health
R. Saliba, D. Karam-Sarkis, J-R Zahar, L. S. A. Glele
Summary: This study aimed to assess whether there are physical and psychological adverse events associated with patient isolation based on newly published studies. Through a systematic literature review and meta-analysis, the findings showed no adverse events related to clinical care or patients' experience associated with patient isolation. However, further studies with proper methodology are needed to confirm these results.
JOURNAL OF HOSPITAL INFECTION
(2022)
Article
Health Care Sciences & Services
Petra Eid, Louis Arnould, Pierre-Henry Gabrielle, Ludwig S. Aho, Michel Farnier, Catherine Creuzot-Garcher, Yves Cottin
Summary: This study investigated the relationship between retinal microvascular changes and atherosclerotic plaques in patients with familial hypercholesterolemia (FH) compared to volunteers without FH. The findings show that retinal microvascularization is altered in FH, and retinal vascular densities are modified according to the Coronary Artery Calcium (CAC) score.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Ophthalmology
Victoire Hurand, Jean-Baptiste Ducloyer, Florian Baudin, Serge Aho, Michel Weber, Laurent Kodjikian, Francois Devin, Pierre-Henry Gabrielle, Catherine Creuzot-Garcher, Pascale Massin
Summary: The study evaluates the impact of adherence to French COVID-19 guidelines on visual outcomes in patients receiving anti-VEGF treatment for macular diseases. Strict adherence to guidelines was associated with better visual outcomes, but most patients did not attend as planned.
ACTA OPHTHALMOLOGICA
(2023)
Article
Otorhinolaryngology
Dhari Al Burshaid, Morgane Corda, Serge Aho-Glele, Caroline Guigou, Mohamed Al Shehabi, Mireille Folia
Summary: This article describes the tendencies of vocal rehabilitation post total laryngectomy (TL) in France and compares it with other countries. The survey results show that tracheoesophageal speech (TES) is the most practiced modality, either alone or in combination with esophageal speech (ES).
ACTA OTO-LARYNGOLOGICA
(2023)
Article
Clinical Neurology
Pauline Jakubina, Alexandre Meloux, Gauthier Duloquin, Serge Aho, Catherine Vergely, Yannick Bejot
Summary: This study aimed to assess the association between plasma Growth Differentiation Factor-8 (GDF-8)/Myostatin levels and outcome of ischemic stroke (IS) patients. The results showed that lower plasma GDF-8 levels were associated with a poorer functional outcome in IS patients treated with acute revascularization therapy. However, the underlying pathophysiological mechanisms involving GDF-8 in post-stroke outcome remain to be elucidated.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2023)
Article
Medicine, General & Internal
Petra Eid, Catherine Creuzot-Garcher, Ludwig Serge Aho, Pierre-Henry Gabrielle, Estelle Charpin, Dea Haddad, Laure-Anne Steinberg, Alain Bron, Bruno Verges, Louis Arnould
Summary: This study analyzed retinal vascular parameters in type 1 diabetes patients without diabetic retinopathy using OCT-A and found lower vascular density in the SCP. Additionally, there was a correlation between central vascular density in the DCP and total daily insulin intake, and the use of the FSL device was associated with higher vascular densities in both the SCP and DCP.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Anne-Laure Soilly, Ludwig Serge Aho Glele, Alain Bernard, Halim Abou Hanna, Marc Filaire, Pierre Magdaleinat, Charles Marty-Ane, Francois Tronc, Renaud Grima, Jean-Marc Baste, Pascal-Alexandre Thomas, Bertrand Richard De Latour, Arnaud Pforr, Pierre-Benoit Pages
Summary: This study evaluates the real benefits and medico-economic impact of video-thoracoscopy versus open thoracotomy for non-small cell lung cancer in France. The results show that video-thoracoscopy has lower costs at 30 days, but the economic efficiency is not established.
BMC HEALTH SERVICES RESEARCH
(2023)
Letter
Cardiac & Cardiovascular Systems
Kevin Guillen, Anne-Virginie Salsac, Pierre-Olivier Comby, Ludwig Serge Aho-Glele, Olivier Chevallier, Romaric Loffroy
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Review
Medicine, General & Internal
Ludwig Serge Aho Glele, Alexis de Rougemont
Summary: The COVID-19 pandemic has had devastating effects globally, and prevention strategies are crucial. Standard precautions like hand hygiene and mask use are fundamental in infection control. Adequate ventilation is essential for reducing transmission risk in poorly ventilated environments. Regular hand hygiene and proper surface maintenance can minimize the risk of transmission through surface contact. A multifaceted approach, including mask-wearing, ventilation, physical separation, and eye protection, is necessary to prevent SARS-CoV-2 transmission.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Kevin Guillen, Frederic Thony, Costantino Del Giudice, Gilles Goyault, Arthur David, Frederic Douane, Yann Le Bras, Valerie Monnin-Bares, Jean-Francois Heautot, Herve Rousseau, Thomas Martinelli, Francine Thouveny, Pierre-Antoine Barral, Vincent Le Pennec, Pascal Chabrot, Andre Rogopoulos, Ludwig Serge Aho-Glele, Marc Sapoval, Mathieu Rodiere, Olivier Chevallier, Nicolas Falvo, Romaric Loffroy, V French Soc Cardiovasc Imaging SFIC
Summary: We investigated the differences between patient-reported outcomes and objective criteria in angioplasty/stenting for post-thrombotic syndrome. The results showed that patient-reported outcomes were more consistent and effective in the diagnosis and follow-up of patients with PTS compared to radiologic patency.
Article
Radiology, Nuclear Medicine & Medical Imaging
Diana M. Marin-Castrillon, Leonardo Geronzi, Arnaud Boucher, Siyu Lin, Marie-Catherine Morgant, Alexandre Cochet, Michel Rochette, Sarah Leclerc, Khalid Ambarki, Ning Jin, Ludwig Serge Aho, Alain Lalande, Olivier Bouchot, Benoit Presles
Summary: The objective of this study is to evaluate the performance of two automatic segmentation methods in the calculation of aortic wall pressure. The results showed that the deep learning approach presented the best segmentation performance and provided lower calculation errors compared to the multi-atlas method.
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
(2023)
Article
Endocrinology & Metabolism
Pauline Legris, Benjamin Bouillet, Justine Paris, Pauline Pistre, Madeline Devaux, Stephanie Bost, Isabelle Simoneau, Sylvain Manfredi, Antoine Drouillard, Jean-Noel Bastie, Marie Chaix, Pamela Massoud, Alexia Rouland, Serge Aho, Mathieu Boulin, Jean-Michel Petit
Summary: The aim of the study was to assess the glucose profile in people with diabetes starting chemotherapy using Continuous Glucose Monitoring (CGM). The results showed that CGM could reduce the risk of hypoglycemia in these patients, supporting the recommendation of assessing hypoglycemia risk before starting chemotherapy.
ACTA DIABETOLOGICA
(2023)
Review
Infectious Diseases
L. S. Aho Glele, E. Simon, C. Bouit, M. Serrand, L. Filipuzzi, K. Astruc, P. Kadhel, P. Sagot
Summary: Through a sensitivity analysis, this study suggests that SARS-CoV-2 infection during pregnancy is associated with preterm birth and may be associated with preeclampsia, while more data are needed to draw conclusions about stillbirth.
INFECTIOUS DISEASES NOW
(2022)
Article
Health Care Sciences & Services
Wendy De Guglielmo, Jean Michel Rebibou, Serge Aho, Thomas Rogier, Gilles Nuemi, Claude Girard, Eric Steinmetz, Mathieu Legendre
Summary: This study identified risk factors for acute kidney injury (AKI) among patients aged over 65 based on pre-operative variables. Pre-operative creatinine level, history of respiratory insufficiency, prior vascular surgery, and abdominal surgery were associated with an increased risk of post-operative AKI. A history of renal disease was specifically associated with increased risk in cases of vascular or abdominal surgery.
