Article
Clinical Neurology
Tai Ren, Priscilla Ming Yi Lee, Fei Li, Jiong Li
Summary: This study aimed to investigate whether children born to mothers who used carbamazepine during pregnancy had worse academic performance in adolescence. The results showed that offspring exposed to maternal carbamazepine monotherapy during pregnancy had lower scores in Danish and mathematics in the ninth-grade exit examination.
Article
Substance Abuse
Michael J. Bray, Li-Shiun Chen, Louis Fox, Yinjiao Ma, Richard A. Grucza, Sarah M. Hartz, Robert C. Culverhouse, Nancy L. Saccone, Dana B. Hancock, Eric O. Johnson, James D. McKay, Timothy B. Baker, Laura J. Bierut
Summary: This study examines the predictive utility of polygenic risk scores for smoking behaviors. Results show that in European ancestry cohorts, smoking-related PRSs were significantly associated with smoking behaviors, while in African ancestry cohorts, the PRSs did not predict smoking behaviors.
NICOTINE & TOBACCO RESEARCH
(2021)
Article
Obstetrics & Gynecology
X. Liu, M. Kayser, S. A. Kushner, H. Tiemeier, F. Rivadeneira, V. W. V. Jaddoe, W. J. Niessen, E. B. Wolvius, G. Roshchupkin
Summary: This study found that low-to-moderate levels of prenatal alcohol exposure (PAE) were associated with children's facial shape, even at levels below 12 g of alcohol per week. However, this association diminished as children grew older.
HUMAN REPRODUCTION
(2023)
Article
Environmental Sciences
Yafei Tan, Jiaqiang Liao, Bin Zhang, Hong Mei, Anna Peng, Jinzhu Zhao, Yan Zhang, Shaoping Yang, Meian He
Summary: The study found that exposure to air pollution during pregnancy may affect childhood growth trajectories. Prenatal exposure to PM10 and CO was associated with slow growth trajectory in children, while exposure to NO2 increased the risk of both slow and rapid growth trajectories.
ENVIRONMENTAL RESEARCH
(2021)
Article
Environmental Sciences
Pengpeng Wang, Yingya Zhao, Jialin Li, Yuhan Zhou, Ranran Luo, Xia Meng, Yunhui Zhang
Summary: The study found a significant association between prenatal PM2.5 exposure and decreased neurodevelopmental scores in children at ages 2, 6, and 24 months. Each 10 µg/m³ increase in PM2.5 exposure was significantly associated with an increased risk of developmental delay, especially in the problem-solving domain for girls.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Substance Abuse
Ulrich John, Hans-Jurgen Rumpf, Monika Hanke, Christian Meyer
Summary: This study aimed to analyze the relationship between risky alcohol drinking, tobacco smoking, alcohol and nicotine dependence, and the time until the first cigarette in the morning in relation to mortality. The findings suggest that these factors are associated with each other and can predict the time to death. In addition, individuals with a history of alcohol dependence who currently smoke their first cigarette within 30 minutes of waking up have a higher risk of early death compared to low-risk alcohol consumers who have never smoked.
EUROPEAN ADDICTION RESEARCH
(2023)
Article
Psychiatry
Bereket Duko, Gavin Pereira, Robert J. Tait, Kim Betts, John Newnham, Rosa Alati
Summary: This study found a significant association between prenatal tobacco exposure and an increased risk of anxiety symptoms in young adults, while there was insufficient statistical evidence to support an association between prenatal alcohol exposure and the risk of anxiety symptoms.
PSYCHIATRY RESEARCH
(2022)
Article
Pediatrics
Hsin-Chien Yen, Chien-Heng Lin, Ming-Chih Lin, Ya-Chi Hsu, Yi-Hsuan Lin
Summary: This article explores the impact of prenatal exposure to air pollution on the occurrence of immune thrombocytopenia (ITP) in children.
FRONTIERS IN PEDIATRICS
(2022)
Article
Public, Environmental & Occupational Health
Oscar M. Camacho, Andrew Hill, Stacy Fiebelkorn, Aaron Williams, James Murphy
Summary: The study suggests that more complex models may be needed to assess interactions between multiple coexisting products in the marketplace. Data availability may hinder the effectiveness of three-product models, while two-product models could miss potential synergies between products. Scenario analyses for THPs and e-cigarettes in Italy show reductions in life-years lost, with larger reductions seen in the Japanese THP scenario compared to the USA e-cigarette projections.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Krishna Subedi, Ashish Shrestha, Tarakant Bhagat
Summary: The study found high levels of nicotine dependence among smokers and smokeless tobacco users visiting dental outreach programs. It is recommended to develop policies to control tobacco use and establish tobacco cessation centers.
Article
Substance Abuse
Anne Buu, Zhanrui Cai, Runze Li, Su-Wei Wong, Hsien-Chang Lin, Wei-Chung Su, Douglas E. Jorenby, Megan E. Piper
Summary: This study validates e-cigarette dependence scales using dynamic patterns of e-cigarette use behaviors and finds that more stable use patterns are associated with higher levels of dependence. Additionally, the dependence scales may capture the average consumption but not the instability of product-specific consumption.
NICOTINE & TOBACCO RESEARCH
(2021)
Article
Psychiatry
Gregory S. Chasson, Junhan Cho, Mark Zimmerman, Adam M. Leventhal
Summary: This study provides evidence for the comorbidity between obsessive-compulsive symptoms and nicotine dependence in clinical and non-clinical populations. The results suggest that the link between obsessive-compulsive symptoms and nicotine dependence may be obscured when obsessive-compulsive phenomena is modeled as a dichotomous diagnostic variable rather than as a dimensional construct.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Environmental Sciences
Vinoj H. Sewberath Misser, Ashna D. Hindori-Mohangoo, Arti Shankar, Jeffrey K. Wickliffe, Maureen Y. Lichtveld, Dennis R. A. Mans
Summary: Globally, prenatal exposure to environmental contaminants such as mercury, manganese, and lead is increasingly linked to adverse birth outcomes. This study in Suriname found no statistically significant relationship between blood levels of mercury, manganese, or lead and stillbirth, preterm birth, low birth weight, and low Apgar score. However, diabetes mellitus was independently associated with preterm birth and hypertension with low birth weight.
Article
Oncology
Shao-Hua Xie, Giola Santoni, Jesper Lagergren
Summary: The study suggests that menopausal hormonal therapy in women may decrease the risk of oesophageal adenocarcinoma, especially for users younger than 60 years old.
BRITISH JOURNAL OF CANCER
(2022)
Article
Public, Environmental & Occupational Health
Elena Dudukina, Szimonetta Komjathine Szepligeti, Par Karlsson, Kofi Asomaning, Anne Kjersti Daltveit, Katja Hakkarainen, Fabian Hoti, Helle Kieler, Astrid Lunde, Ingvild Odsbu, Matti Rantanen, Johan Reutfors, Laura Saarelainen, Vera Ehrenstein, Gunnar Toft
Summary: This study investigated the association between prenatal exposure to pregabalin and the risks of adverse birth and postnatal neurodevelopmental outcomes. The findings suggest a possible link between prenatal pregabalin exposure and increased risk of stillbirth and major congenital malformations.
Article
Psychology, Developmental
Beata Jablonska, Kyriaki Kosidou, Antonio Ponce de Leon, Bjorn Wettermark, Cecilia Magnusson, Henrik Dal, Christina Dalman
JOURNAL OF ATTENTION DISORDERS
(2020)
Article
Biochemistry & Molecular Biology
Gustaf Brander, Ralf Kuja-Halkola, Mina A. Rosenqvist, Christian Ruck, Eva Serlachius, Lorena Fernandez de la Cruz, Paul Lichtenstein, James J. Crowley, Henrik Larsson, David Mataix-Cols
Summary: OCD is a familial disorder, but the risk of developing OCD is significantly higher in relatives of individuals with tic-related OCD compared to those with non-tic-related OCD. These findings suggest that tic-related OCD may be a distinct and particularly familial subtype of OCD, which has implications for genetic research efforts in the future.
MOLECULAR PSYCHIATRY
(2021)
Article
Pediatrics
Isabelle Le Ray, Chen Wang, Catarina Almqvist, Paul Lichtenstein, Brian M. D'Onofrio, Stefan Johansson, Henrik Larsson, Mina A. Rosenqvist
Summary: At a population level, children treated for neonatal jaundice had an increased risk of ADHD. However, in the sibling comparisons, there was no clear association between neonatal jaundice and ADHD. This suggests that the association between neonatal jaundice and ADHD is likely influenced by shared familial factors.
Article
Education & Educational Research
Hanna Hultin, Laura Ferrer-Wreder, Karin Engstrom, Filip Andersson, Maria Rosaria Galanti
Summary: Schools with favorable school climate have lower rates of bullying victimization reported by students. Improving school climate has the potential to positively impact students academically and socially, as well as reduce the prevalence of bullying.
JOURNAL OF SCHOOL HEALTH
(2021)
Article
Psychiatry
Sanjiv Risal, Maria Manti, Haojiang Lu, Romina Fornes, Henrik Larsson, Anna Benrick, Qiaolin Deng, Carolyn E. Cesta, Mina A. Rosenqvist, Elisabet Stener-Victorin
Summary: This study found that daughters of women with PCOS have an increased risk of anxiety disorders, possibly transmitted transgenerationally through the female germline. Using a PCOS mouse model, researchers observed anxiety-like behavior in female offspring in the androgenized lineage and male offspring in both the androgenized and obese lineages. Additionally, dysregulated genes related to anxiety-like behavior were identified in the amygdala of female offspring in the androgenized lineage and male offspring in the obese lineage.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Medicine, General & Internal
Anni-Maria Pulkki-Brannstrom, Maria R. Galanti, Maria Nilsson
Summary: Despite a long-term downward trend in smoking prevalence in Sweden, tobacco remains a leading risk factor for death and disability. This article describes the planned evaluation of a school-based program to prevent tobacco use in adolescents, focusing on cost-effectiveness and health equity impact. The study will assess the cost-effectiveness of the program and its potential impact on education-related inequalities in smoking initiation and cessation.
Article
Psychiatry
Elena Raffetti, Philippe Anastasios Melas, Anton Jonatan Landgren, Filip Andersson, Yvonne Forsell, Catharina Lavebratt, Maria Rosaria Galanti
Summary: Early life stress is associated with increased methylation of the NR3C1 gene, and this hypermethylation can predict substance use in middle adolescence, particularly recent use and use duration. Additional longitudinal studies are needed to confirm these findings.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Psychiatry
Torkel Carlsson, Mina Rosenqvist, Agnieszka Butwicka, Henrik Larsson, Sebastian Lundstrom, Pei-Yin Pan, Karl Lundin Remnelius, Mark J. Taylor, Sven Bolte
Summary: This study suggests that, in addition to genetic factors, environmental exposures contribute to the development of autism spectrum disorder (ASD). The cumulative stress hypothesis of ASD is supported, with higher early cumulative exposure loads being associated with an increased risk of ASD diagnosis and autistic symptoms.
TRANSLATIONAL PSYCHIATRY
(2022)
Review
Substance Abuse
Linnea Hedman, Maria R. Galanti, Lotta Ryk, Hans Gilljam, Louise Adermark
Summary: This study did not find sufficient evidence for an association between e-cigarette use and smoking cessation. Although randomized controlled trials tended to support a more positive association between e-cigarette use and smoking cessation, the quality of evidence remained consistently low.
TOBACCO PREVENTION & CESSATION
(2021)
Article
Obstetrics & Gynecology
Paul Madley-Dowd, Jessica Rast, Viktor H. H. Ahlqvist, Caichen Zhong, Florence Z. Z. Martin, Neil M. M. Davies, Kristen Lyall, Craig Newschaffer, Torbjorn Tomson, Cecilia Magnusson, Dheeraj Rai, Brian K. K. Lee, Harriet Forbes
Summary: This study examined the prescription of antiseizure medication (ASM) during pregnancy and found an increase in prescription rates, especially among women with indications other than epilepsy. Continuous use of ASMs during pregnancy was more common in women with epilepsy. Factors associated with discontinuation included age ≥35, higher social deprivation, frequent contact with the GP, and prescription of antidepressants or antipsychotics.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Ahmed N. Shaaban, Filip Andersson, Cecilia Magnusson, Nicola Orsini, Ida H. Caspersen, Sebastian Pena, Sakari Karvonen, Per Magnus, Maria R. Galanti
Summary: Separating non-smokers from former smokers is crucial in assessing disease risk or prognosis to avoid bias. This study found that former smokers had a higher risk of COVID-19 diagnosis, hospital admission, and death compared to non-smokers, while current smoking was negatively associated with the risk of COVID-19.
SCANDINAVIAN JOURNAL OF PUBLIC HEALTH
(2023)
Article
Psychology, Developmental
Mark J. Taylor, Joanna Martin, Agnieszka Butwicka, Paul Lichtenstein, Brian D'Onofrio, Sebastian Lundstrom, Henrik Larsson, Mina A. Rosenqvist
Summary: The prevalence of ADHD has increased, but the genetic and environmental factors contributing to it have remained stable.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Psychiatry
Aleksandra Kanina, Henrik Larsson, Arvid Sjolander, Agnieszka Butwicka, Mark J. J. Taylor, Miriam I. I. Martini, Paul Lichtenstein, Frida E. E. Lundberg, Brian M. D. Onofrio, Mina A. A. Rosenqvist
Summary: Cumulative exposure to psychosocial adversity at an early age has been found to increase the risk of ADHD and autism, but it is unclear if this association is causal or due to familial confounding. This study used a population-based cohort in Sweden to examine the relationship between cumulative psychosocial adversity and neurodevelopmental conditions. The results showed a dose-response relationship between psychosocial adversity and ADHD, but no clear dose-response relationship for autism. The findings also highlighted the importance of accounting for familial confounding in studies of psychosocial adversity and neurodevelopmental conditions.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Psychology, Developmental
Melody Almroth, Krisztina D. Laszlo, Kyriaki Kosidou, Maria Rosaria Galanti
Summary: Positive school climate rated by teachers is associated with an increased likelihood of adolescents aiming for a university education, while student-rated school climate does not have the same predictive power. Future research should aim to clarify which aspects of school climate may influence students' academic aspirations.
CHILD & YOUTH CARE FORUM
(2021)
Article
Substance Abuse
Erica Sundin, Maria Rosaria Galanti, Jonas Landberg, Mats Ramstedt
Summary: Women are more likely to suffer severe harm from others' drinking, and there are different experiences of severe harm from known drinkers between men and women based on their drinking behavior. These differences indicate a super-additive interaction, and signs of alcohol dependence among women further elevate this interaction.
DRUG AND ALCOHOL REVIEW
(2021)
