Article
Orthopedics
Helen Hoi Lun Tsang, Carlos King Ho Wong, Prudence Wing Hang Cheung, Chak Sing Lau, Ho Yin Chung, Jason Pui Yin Cheung
Summary: The EQ-5D health measure demonstrates satisfactory responsiveness for assessing changes in SpA disease activity, showing good correlations with BASDAI and BASFI scores.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Health Care Sciences & Services
Alex Bato, Valentin Brodszky, L. Hunor Gergely, Krisztian Gaspar, Norbert Wikonkal, Agnes Kinyo, Akos Szabo, Zsuzsanna Beretzky, Andrea Szegedi, Eva Remenyik, Norbert Kiss, Miklos Sardy, Fanni Rencz
Summary: The study aimed to compare the measurement properties of two adult versions of EQ-5D in patients with Hidradenitis suppurativa (HS), with EQ-5D-5L outperforming EQ-5D-3L in terms of feasibility, informativity, and validity for important clinical characteristics. EQ-5D-5L was recommended for assessing HS patients across various settings.
QUALITY OF LIFE RESEARCH
(2021)
Article
Health Care Sciences & Services
Katarzyna Mlynczak, Dominik Golicki
Summary: This study compared the psychometric properties of the EQ-5D-5L questionnaire with the EQ-5D-3L version and EQ VAS in the general adult population of Poland. It found that the EQ-5D-5L had similar or better psychometric properties compared to its EQ-5D-3L equivalent. The novel approach of using a machine learning technique known as the random forest algorithm for construct validity assessment proved to be effective.
QUALITY OF LIFE RESEARCH
(2021)
Article
Health Care Sciences & Services
Vu Quynh Mai, Kim Bao Giang, Hoang Van Minh, Lars Lindholm, Sun Sun, Klas Goran Sahlen
Summary: This study provides EQ-5D-5L population norms for the general population in Vietnam and demonstrates the known-groups validity of EQ-5D-5L instrument among people living with hypertension there. Results show that EQ-VAS and EQ-5D-5L indexes were higher among younger, male, more educated, employed, and single individuals. Statistically significant associations were found between lower EQ-5D-5L indexes and EQ-VAS among people diagnosed with hypertension, those with increasing comorbidities, and obese individuals.
QUALITY OF LIFE RESEARCH
(2022)
Article
Economics
Maike Stolz, Christian Albus, Manfred E. Beutel, Hans-Christian Deter, Kurt Fritzsche, Christoph Herrmann-Lingen, Matthias Michal, Katja Petrowski, Joram Ronel, Jobst-Hendrik Schultz, Wolfgang Sollner, Cora Weber, Martina de Zwaan, Christian Krauth
Summary: This study assessed the responsiveness and convergent validity of the EQ-5D-3L and SF-6D in patients with depressive symptoms. The results showed that both the convergent validity and responsiveness of the SF-6D were better than those of the EQ-5D-3L in these patients. Therefore, the SF-6D is more recommendable for use in studies evaluating interventions for this population.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Oncology
Nasrin Moradi, Thomas G. Poder, Hossein Safari, Mohammad M. Mojahedian, Hosein Ameri
Summary: This study aimed to test the validity and reliability of the EQ-5D-5L (5L) in cancer patients compared to EQ-5D-3L (3L). The results showed that compared to 3L, 5L performed better in terms of ceiling effect, inconsistency, discriminatory power, convergent validity, and relative efficiency.
FRONTIERS IN ONCOLOGY
(2022)
Article
Psychology, Multidisciplinary
Kenneth Sandin, Gemma E. Shields, Ragne G. H. Gjengedal, Kare Osnes, Marianne Tranberg Bjorndal, Odin Hjemdal
Summary: This study found indication of validity for the EQ-5D in patients at risk of or experiencing depression and anxiety, showing sensitivity to symptom severity and functional impairment. Depression and anxiety scores were the primary determinants of the EQ-5D value, with sick leave, subjective health complaints, and gender also contributing to the value.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Economics
Guizhi Weng, Yanming Hong, Nan Luo, Clara Mukuria, Jie Jiang, Zhihao Yang, Sha Li
Summary: This study compares the measurement properties of EQ-5D-3L and EQ-5D-5L in quantifying health-related quality of life burden for four different health conditions in China. The results showed that EQ-5D-5L demonstrated superior performance in terms of higher sensitivity to mild health problems, better relative efficiency, and responses and index value distributions.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Health Care Sciences & Services
Norma B. Bulamu, Ravi Vissapragada, Gang Chen, Julie Ratcliffe, Louise A. Mudge, B. Mark Smithers, Elizabeth A. Isenring, Lorelle Smith, Glyn G. Jamieson, David Watson
Summary: This study evaluated the responsiveness and convergent validity of two preference-based measures in assessing short-term health related quality of life after esophagectomy. The results showed that QLU-C10D was more sensitive to utility changes following esophagectomy compared to EQ-5D-3L.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2021)
Article
Health Care Sciences & Services
Admassu N. Lamu, Lars Bjorkman, Harald J. Hamre, Terje Alraek, Frauke Musial, Bjarne Robberstad
Summary: The study evaluated the validity and responsiveness of two health utility instruments in patients with health complaints attributed to dental amalgam fillings, showing EQ-5D-5L to be more responsive than SF-6D. However, both instruments were less efficient in detecting minimal important changes compared to criteria-based measures.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2021)
Article
Health Care Sciences & Services
Janine Verstraete, Zara Marthinus, Stewart Dix-Peek, Des Scott
Summary: This study aimed to compare the instrument performance and responsiveness of the EQ-5D-Y-3L and the expanded English version of the EQ-5D-Y-5L in children and adolescents receiving acute orthopaedic management in South Africa. The results showed that the EQ-5D-Y-5L performed better, reducing the ceiling effect and demonstrating greater discriminatory power.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2022)
Article
Rehabilitation
Olivia Ernstsson, Kerstin Hagberg, Mathieu F. Janssen, Gouke J. Bonsel, Seher Korkmaz, Niklas Zethraeus, Emelie Heintz
Summary: The study found that EQ-5D-5L has improved informativity, as well as better convergent and known-group validity in patients with major lower limb amputation compared to EQ-5D-3L.
DISABILITY AND REHABILITATION
(2022)
Article
Public, Environmental & Occupational Health
Tzu-Hung Liu, Andrew D. Ho, Yu-Tien Hsu, Chih-Cheng Hsu
Summary: The study provided validity evidence for EQ-5D in Taiwan's National Health Interview Survey in 2013 and identified the most informative items for assessing quality of life in patients with chronic diseases using IRT. EQ-5D scores showed moderate internal consistency and correlation with SF-36 scores, suggesting its potential use in the general population and clinical settings.
Article
Health Care Sciences & Services
Kenneth Sandin, Gemma Shields, Ragne G. H. Gjengedal, Kare Osnes, Marianne T. Bjorndal, Silje E. Reme, Odin Hjemdal
Summary: This study compared the scores of the EQ-5D with scores from questionnaires measuring symptoms of depression and anxiety. The results showed that the EQ-5D can be a useful tool for understanding the impact of depression and anxiety.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2023)
Article
Multidisciplinary Sciences
Paul O'Halloran, Courtney Sullivan, Kiera Staley, Matthew Nicholson, Erica Randle, Adrian Bauman, Alex Donaldson, Nicola McNeil, Arthur Stukas, Annemarie Wright, Michael Kingsley
Summary: This study aimed to assess the validity of a single item measure (SIM) in detecting change in physical activity levels in adolescents. The results showed that the SIM is adequate for assessing physical activity at a single time point but not recommended for assessing change.
Article
Psychology, Developmental
Fiona Kehinde, Aamena Valiji Bharmal, Ian M. Goodyer, Raphael Kelvin, Bernadka Dubicka, Nick Midgley, Peter Fonagy, Peter B. Jones, Paul Wilkinson
Summary: Research showed that adolescents with psychotic symptoms had more severe depression at baseline, but there was no clear association at follow-up. This suggests that psychotic symptoms are not a baseline marker of treatment response.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2022)
Review
Psychology, Clinical
Anna B. Chaplin, Natasha F. Daniels, Diana Ples, Rebecca Z. Anderson, Amy Gregory-Jones, Peter B. Jones, Golam M. Khandaker
Summary: High BMI and smoking are associated with subsequent depression in young people, while low but not high SBP increases the risk of depression. The generalizability of the findings may be limited as most studies were based in North America or Europe.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Developmental
Emma Soneson, Stephen Puntis, Nikki Chapman, Karen L. Mansfield, Peter B. Jones, Mina Fazel
Summary: Relatively little research has been done on children and young people whose mental health and wellbeing improved during the Covid-19 lockdown. In this study, one-third of the participating CYP reported improved mental wellbeing during the first UK national lockdown. These CYP had better relationships with friends and family, experienced less loneliness and exclusion, faced reduced bullying, managed school tasks better, and engaged in more sleep and exercise compared to their peers who reported no change or deterioration in mental wellbeing. Understanding why these CYP fared better during lockdown and finding ways to sustain these positive experiences beyond the pandemic can contribute to promoting the future mental health and wellbeing of school-aged CYP.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Developmental
Jan Stochl, Hannah Jones, Emma Soneson, Adam P. Wagner, Golam M. Khandaker, Stanley Zammit, Jon Heron, Gemma Hammerton, Edward T. Bullmore, Ray Dolan, Peter Fonagy, Ian M. Goodyer, J. Perez, Peter B. Jones
Summary: Characterizing patterns of mental phenomena in epidemiological studies of adolescents can provide insight into the latent organization of psychiatric disorders. This avoids the biases of chronicity and selection inherent in clinical samples, guides models of shared aetiology within psychiatric disorders and informs the development and implementation of interventions.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Clinical
Victoria Rodriguez, Luis Alameda, Diego Quattrone, Giada Tripoli, Charlotte Gayer-Anderson, Edoardo Spinazzola, Giulia Trotta, Hannah E. Jongsma, Simona Stilo, Caterina La Cascia, Laura Ferraro, Daniele La Barbera, Antonio Lasalvia, Sarah Tosato, Ilaria Tarricone, Elena Bonora, Stephane Jamain, Jean-Paul Selten, Eva Velthorst, Lieuwe de Haan, Pierre-Michel Llorca, Manuel Arrojo, Julio Bobes, Miguel Bernardo, Celso Arango, James Kirkbride, Peter B. Jones, Bart P. Rutten, Alexander Richards, Pak C. Sham, Michael O'Donovan, Jim Van Os, Craig Morgan, Marta Di Forti, Robin M. Murray, Evangelos Vassos
Summary: This study suggests that combining polygenic risk scores (PRS) for severe psychiatric disorders with prediction models for psychosis phenotypes can improve discrimination ability and enhance our understanding of these phenotypes. PRS may have potential usefulness in specific populations such as those at high risk or in the early stages of psychosis.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Andrew J. Watson, Annalisa Giordano, John Suckling, Thomas R. E. Barnes, Nusrat Husain, Peter B. Jones, Carl R. Krynicki, Stephen M. Lawrie, Shon Lewis, Naghmeh Nikkheslat, Carmine M. Pariante, Rachel Upthegrove, Bill Deakin, Paola Dazzan, Eileen M. Joyce
Summary: This study identified cognitive subtypes based on IQ in patients with early-phase schizophrenia-spectrum disorder. The compromised IQ subtype was associated with smaller brain volume and higher levels of low-grade inflammation markers. This adds validity to the existence of a neurodevelopmental subtype of schizophrenia.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Monica Aas, Luis Alameda, Marta Di Forti, Diego Quattrone, Paola Dazzan, Antonella Trotta, Laura Ferraro, Victoria Rodriguez, Evangelos Vassos, Pak Sham, Giada Tripoli, Caterina La Cascia, Daniele La Barbera, Ilaria Tarricone, Roberto Muratori, Domenico Berardi, Antonio Lasalvia, Sarah Tosato, Andrei Szoke, Pierre-Michel Llorca, Celso Arango, Andrea Tortelli, Lieuwe de Haan, Eva Velthorst, Julio Bobes, Miguel Bernardo, Julio Sanjuan, Jose Luis Santos, Manuel Arrojo, Cristina Marta Del-Ben, Paulo Rossi Menezes, Jean-Paul Selten, Peter B. Jones, Hannah E. Jongsma, James B. Kirkbride, Bart P. F. Rutten, Jim van Os, Charlotte Gayer-Anderson, Robin M. Murray, Craig Morgan
Summary: This study found possible synergistic effects of childhood adversity experiences and high polygenic risk scores for schizophrenia in the onset of first-episode psychosis. However, larger samples are needed for more precise estimation.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Lucia Sideli, Adriano Schimmenti, Daniele La Barbera, Caterina La Cascia, Laura Ferraro, Monica Aas, Luis Alameda, Eva Velthorst, Helen L. Fisher, Vincenzo Caretti, Giulia Trotta, Giada Tripoli, Diego Quattrone, Charlotte Gayer-Anderson, Fabio Seminerio, Crocettarachele Sartorio, Giovanna Marrazzo, Antonio Lasalvia, Sarah Tosato, Ilaria Tarricone, Domenico Berardi, Giuseppe D'Andrea, Celso Arango, Manuel Arrojo, Miguel Bernardo, Julio Bobes, Julio Sanjuan, Jose Luis Santos, Paulo Rossi Menezes, Cristina Marta Del-Ben, Hannah E. Jongsma, Peter B. Jones, James B. Kirkbride, Pierre-Michel Llorca, Andrea Tortelli, Baptiste Pignon, Lieuwe de Haan, Jean-Paul Selten, Jim Van Os, Bart P. Rutten, Marta Di Forti, Craig Morgan, Robin M. Murray
Summary: Our study emphasizes the impact of childhood maltreatment on academic outcomes and cognition of individuals with first-episode psychosis and controls. Childhood maltreatment is associated with lower educational attainment and IQ, particularly evident in controls. While negative associations between childhood maltreatment and educational attainment were observed in both affective and nonaffective psychoses, the crude association with IQ was only evident in affective psychoses.
SCHIZOPHRENIA BULLETIN
(2022)
Article
Psychology, Clinical
Maria Protsenko, Martta Kerkela, Jouko Miettunen, Juha Auvinen, Marjo-Riitta Jarvelin, Peter B. Jones, Mika Gissler, Juha Veijola
Summary: There is a familial association between parental severe mental illness (SMI) and obesity in middle-aged offspring, especially in the offspring of mothers with SMI.
PSYCHOLOGICAL MEDICINE
(2023)
Review
Family Studies
Emma Soneson, Shruti Das, Anne-Marie Burn, Marije van Melle, Joanna K. Anderson, Mina Fazel, Peter Fonagy, Tamsin Ford, Ruth Gilbert, Katie Harron, Emma Howarth, Ayla Humphrey, Peter B. Jones, Anna Moore
Summary: This scoping review provides an overview of studies using administrative data linkage to study child maltreatment. The findings demonstrate the importance of data linkage in the public health response to child maltreatment. However, further research is needed to translate research into effective service development and monitoring.
CHILD MALTREATMENT
(2023)
Article
Psychiatry
Nina M. Lutz, Sharon A. S. Neufeld, Roxanne W. Hook, Peter B. Jones, Edward T. Bullmore, Ian M. Goodyer, Tamsin J. Ford, Samuel R. Chamberlain, Paul O. Wilkinson
Summary: Non-suicidal self-injury (NSSI) is more common among women, possibly due to their higher levels of psychological distress. Women also show significant differences in sensation seeking and positive urgency compared to men. Psychological distress partially mediates the relationship between gender and NSSI.
ARCHIVES OF SUICIDE RESEARCH
(2023)
Article
Psychiatry
Noham Wolpe, Shanquan Chen, Brian Kirkpatrick, Peter B. Jones, Christopher Jenkins, Rudolf N. Cardinal, Emilio Fernandez-Egea
Summary: Negative symptoms of schizophrenia, such as reduced motivation and impaired emotional expressivity, can be influenced by antipsychotic-induced sedation. This study found that sedation adversely affected motivation but not emotional expressivity in clozapine-treated patients. Clozapine also indirectly impaired motivation through worsening sedation, but after considering sedation, it improved motivation. These findings emphasize the importance of addressing sedative side-effects of antipsychotics for better clinical outcomes.
BRITISH JOURNAL OF PSYCHIATRY
(2023)
Letter
Psychiatry
Noham Wolpe, Shanquan Chen, Brian Kirkpatrick, Peter B. Jones, Christopher Jenkins, Rudolf N. Cardinal, Emilio Fernandez-Egea
BRITISH JOURNAL OF PSYCHIATRY
(2023)
Review
Health Care Sciences & Services
Antonia Errazuriz, Dalia Avello-Vega, Juan P. Ramirez-Mahaluf, Rafael Torres, Nicolas A. Crossley, Eduardo A. Undurraga, Peter B. Jones
Summary: This study aimed to systematically review population-based studies of depressive disorder prevalence in Latin America, report regional estimates, and test its association with development indicators. The findings showed a high prevalence of depressive disorders in Latin America, with significant associations with inequality and development indicators. Efforts to improve mental health access and research capabilities in the region are needed to address the major gaps in country representation and high heterogeneity in prevalence.
LANCET REGIONAL HEALTH-AMERICAS
(2023)
Article
Health Care Sciences & Services
Anne-Marie Burn, Tamsin J. Ford, Jan Stochl, Peter B. Jones, Jesus Perez, Joanna K. Anderson
Summary: Artemis-A is a web app designed for assessing the mental health of secondary school students. It uses computerized adaptive testing technology to shorten the assessment process. Through stakeholder consultations and user testing, the research team improved the user interface design and explored the feasibility and acceptability of the app in schools.
JMIR FORMATIVE RESEARCH
(2022)
